MIR517Cinhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner

(2015) Carlotta Giorgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

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C19MC MicroRNAs Regulate the Migration of Human Trophoblasts

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MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

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A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy

(2014) J Noack et al.   Cell Death & Disease

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

(2013) Intissar Akalay et al.   Autophagy

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

(2013) Yuan-Fei Peng et al.   Autophagy

Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition

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Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

(2013) Ilkka Liikanen et al.   MOLECULAR THERAPY

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features

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VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

(2012) Ulf D. Kahlert et al.   CANCER LETTERS

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas

(2012) U.D. Kahlert et al.   CANCER LETTERS

Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2

(2012) Rui-Fang Liu et al.   CANCER LETTERS

Inhibition of autophagy impairs tumor cell invasion in an organotypic model

(2012) Robin L. Macintosh et al.   CELL CYCLE

Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments

(2012) Silvia Palumbo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The dark side of a success story: microRNAs of the C19MC cluster in human tumours

(2012) Inga Flor et al.   JOURNAL OF PATHOLOGY

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma

(2012) Claudia Augello et al.   LIVER INTERNATIONAL

Quantitative Proteomics Reveals Regulation of Karyopherin Subunit Alpha-2 (KPNA2) and Its Potential Novel Cargo Proteins in Nonsmall Cell Lung Cancer

(2012) Chun-I Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

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Autophagy positively regulates the CD44+CD24-/lowbreast cancer stem-like phenotype

(2011) Sílvia Cufí et al.   CELL CYCLE

SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells

(2011) Sung-Pil Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

KPNA2 Expression Is an Independent Adverse Predictor of Biochemical Recurrence after Radical Prostatectomy

(2011) A. Mortezavi et al.   CLINICAL CANCER RESEARCH

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the miR-200 family in epithelial-mesenchymal transition

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Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Arachidonic acid promotes epithelial-to-mesenchymal-like transition in mammary epithelial cells MCF10A

(2010) Raul Martinez-Orozco et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Overexpression of Karyopherin-2 in Epithelial Ovarian Cancer and Correlation With Poor Prognosis

(2010) Min Zheng et al.   OBSTETRICS AND GYNECOLOGY

Misregulated E-Cadherin Expression Associated with an Aggressive Brain Tumor Phenotype

(2010) Laura J. Lewis-Tuffin et al.   PLoS One

An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity

(2009) Yunlan Du et al.   Autophagy

Basal autophagy induction without AMP-activated protein kinase under low glucose conditions

(2009) Tyisha Williams et al.   Autophagy

Frequent Amplification of a chr19q13.41 MicroRNA Polycistron in Aggressive Primitive Neuroectodermal Brain Tumors

(2009) Meihua Li et al.   CANCER CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

(2008) Pauline J. van der Watt et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY