Hypoxia-inducible transcription factors in fish: expression, function and interconnection with the circadian clock

Mammalian Circadian Period, But Not Phase and Amplitude, Is Robust Against Redox and Metabolic Perturbations

(2018) Marrit Putker et al.   ANTIOXIDANTS & REDOX SIGNALING

Metabolic Plasticity Enables Circadian Adaptation to Acute Hypoxia in Zebrafish Cells

(2018) Adolf M. Sandbichler et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes

(2017) Allie M. Graham et al.   PLoS One

Light-sensing via hydrogen peroxide and a peroxiredoxin

(2017) Kristofer Bodvard et al.   Nature Communications

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia

(2017) Hong Lian Li et al.   PLoS One

Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions

(2017) Manuel J. Del Rey et al.   Scientific Reports

The Pentose Phosphate Pathway Regulates the Circadian Clock

(2016) Guillaume Rey et al.   Cell Metabolism

Mitochondrial H 2 O 2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm

(2016)   FREE RADICAL BIOLOGY AND MEDICINE

Global spread of hypoxia in freshwater ecosystems during the last three centuries is caused by rising local human pressure

(2016) Jean-Philippe Jenny et al.   GLOBAL CHANGE BIOLOGY

Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor

(2016) Raymond W. M. Kwong et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Reciprocal Control of the Circadian Clock and Cellular Redox State - a Critical Appraisal

(2016)   MOLECULES AND CELLS

Transcriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvae

(2015) Yong Long et al.   BMC GENOMICS

Genome-wide mapping of Hif-1α binding sites in zebrafish

(2015) David Greenald et al.   BMC GENOMICS

Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models

(2015) P. M. Elks et al.   Disease Models & Mechanisms

Transcriptome analysis of the plateau fish (Triplophysa dalaica): Implications for adaptation to hypoxia in fishes

(2015) Ying Wang et al.   GENE

Evidence for Adaptation to the Tibetan Plateau Inferred from Tibetan Loach Transcriptomes

(2015) Ying Wang et al.   Genome Biology and Evolution

Impaired gamete production and viability in Atlantic croaker collected throughout the 20,000 km 2 hypoxic region in the northern Gulf of Mexico

(2015) Peter Thomas et al.   MARINE POLLUTION BULLETIN

Circadian Oscillation of Sulfiredoxin in the Mitochondria

(2015) In Sup Kil et al.   MOLECULAR CELL

Multiplicity of Hypoxia-Inducible Transcription Factors and Their Connection to the Circadian Clock in the Zebrafish

(2015) Bernd Pelster et al.   PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY

Oxygen Sensing and Homeostasis

(2015) Nanduri R. Prabhakar et al.   PHYSIOLOGY

Developmental Expression and Hypoxic Induction of Hypoxia Inducible Transcription Factors in the Zebrafish

(2015) Louise Köblitz et al.   PLoS One

Analysis of hypoxia-inducible factor alpha polyploidization reveals adaptation to Tibetan plateau in the evolution of schizothoracine fish

(2014) Lihong Guan et al.   BMC EVOLUTIONARY BIOLOGY

Chronodisruption increases cardiovascular risk in zebrafish via reduced clearance of senescent erythrocytes

(2014) Margit Egg et al.   CHRONOBIOLOGY INTERNATIONAL

Transcriptional regulation of hypoxia inducible factors alpha (HIF-α) and their inhibiting factor (FIH-1) of channel catfish (Ictalurus punctatus) under hypoxia

(2014) Xin Geng et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Hypoxia turns genotypic female medaka fish into phenotypic males

(2014) Catis Hin Ying Cheung et al.   ECOTOXICOLOGY

Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis

(2014) Yatrik M. Shah et al.   GASTROENTEROLOGY

Transcriptional divergence of the duplicated hypoxia-inducible factor alpha genes in zebrafish

(2014) Kalle T. Rytkönen et al.   GENE

Human high-altitude adaptation: forward genetics meets the HIF pathway

(2014) Abigail W. Bigham et al.   GENES & DEVELOPMENT

The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light

(2014) Zohar Ben-Moshe et al.   NUCLEIC ACIDS RESEARCH

Hypoxia-inducible factor-1 mediates adaptive developmental plasticity of hypoxia tolerance in zebrafish, Danio rerio

(2014) C. E. Robertson et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia

(2014) Peng Zhang et al.   Cell Reports

The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions

(2013) M. Mastrogiannaki et al.   BLOOD

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

Linking Oxygen to Time: The Bidirectional Interaction Between the Hypoxic Signaling Pathway and the Circadian Clock

(2013) Margit Egg et al.   CHRONOBIOLOGY INTERNATIONAL

Role of redox metabolism for adaptation of aquatic animals to drastic changes in oxygen availability

(2013) Alexis F. Welker et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Regulation of Circadian Clocks by Redox Homeostasis

(2013) Alessandra Stangherlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular characterization and expression analysis of three hypoxia-inducible factor alpha subunits, HIF-1α, -2α and -3α in hypoxia-tolerant Indian catfish, Clarias batrachus [Linnaeus, 1758]

(2013) Vindhya Mohindra et al.   MOLECULAR BIOLOGY REPORTS

Molecular, functional, and gene expression analysis of zebrafish hypoxia-inducible factor-3α

(2012) Peng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

(2012) Melissa Wilking et al.   ANTIOXIDANTS & REDOX SIGNALING

A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis

(2012) Kirankumar Santhakumar et al.   CANCER RESEARCH

SUBFUNCTIONALIZATION OF CYPRINID HYPOXIA-INDUCIBLE FACTORS FOR ROLES IN DEVELOPMENT AND OXYGEN SENSING

(2012) Kalle T. Rytkönen et al.   EVOLUTION

Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia

(2012) Helene Niecknig et al.   FREE RADICAL RESEARCH

Molecular characterization and expression analysis of three hypoxia-inducible factor alpha subunits, HIF-1α/2α/3α of the hypoxia-sensitive freshwater species, Chinese sucker

(2012) Nan Chen et al.   GENE

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

Transcriptional responses to hypoxia are enhanced by recurrent hypoxia (hypoxic preconditioning) in the epaulette shark

(2012) Kalle T. Rytkönen et al.   PHYSIOLOGICAL GENOMICS

Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2

(2012) Nanduri R. Prabhakar et al.   PHYSIOLOGICAL REVIEWS

Passing the baton: the HIF switch

(2012) Mei Yee Koh et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of three IGFBP mRNAs in Atlantic croaker and their regulation during hypoxic stress: potential mechanisms of their upregulation by hypoxia

(2011) Md. Saydur Rahman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Light, Reactive Oxygen Species, and Magnetic Fields Activating ERK/MAPK Signaling Pathway in Cultured Zebrafish Cells

(2011) Yoshimi Uchida et al.   APPLIED MAGNETIC RESONANCE

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response

(2011) Minna Heikkilä et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia: Adapting to High Altitude by Mutating EPAS-1, the Gene Encoding HIF-2α

(2011) Martha C. Tissot van Patot et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Molecular Evolution of the Metazoan PHD–HIF Oxygen-Sensing System

(2011) Kalle T. Rytkönen et al.   MOLECULAR BIOLOGY AND EVOLUTION

HIF-1α mRNA levels in Eurasian perch (Perca fluviatilis) exposed to acute and chronic hypoxia

(2011) Simona Rimoldi et al.   MOLECULAR BIOLOGY REPORTS

HIF signaling and overall gene expression changes during hypoxia and prolonged exercise differ considerably

(2011) Renate Kopp et al.   PHYSIOLOGICAL GENOMICS

Extensive reproductive disruption, ovarian masculinization and aromatase suppression in Atlantic croaker in the northern Gulf of Mexico hypoxic zone

(2011) P. Thomas et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Effects of Hypoxia on Consumption, Growth, and RNA:DNA Ratios of Young Yellow Perch

(2011) James J. Roberts et al.   TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY

Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review

(2011) Paolo E. Porporato et al.   Frontiers in Pharmacology

The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism

(2010) Na Zhang et al.   Cell Metabolism

HIF-1α and -2α genes in a hypoxia-sensitive teleost species Megalobrama amblycephala: cDNA cloning, expression and different responses to hypoxia

(2010) Rui-Jie Shen et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Evolutionary origins of oxygen sensing in animals

(2010) Kalle T Rytkönen et al.   EMBO REPORTS

Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2

(2010) Annika Pasanen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates

(2010) J. F. Storz et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The Ionoregulatory Responses to Hypoxia in the Freshwater Rainbow Trout Oncorhynchus mykiss

(2010) Fathima I. Iftikar et al.   PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY

Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required

(2010) Renate Kopp et al.   PHYSIOLOGICAL GENOMICS

Mitochondrial reactive oxygen species regulate hypoxic signaling

(2009) Robert B Hamanaka et al.   CURRENT OPINION IN CELL BIOLOGY

Hemoglobin enhances oxygen uptake in larval zebrafish (Danio rerio) but only under conditions of extreme hypoxia

(2009) P. Rombough et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Biomarkers of hypoxia exposure and reproductive function in Atlantic croaker: A review with some preliminary findings from the northern Gulf of Mexico hypoxic zone

(2009) Peter Thomas et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Region-wide impairment of Atlantic croaker testicular development and sperm production in the northern Gulf of Mexico hypoxic dead zone

(2009) Peter Thomas et al.   MARINE ENVIRONMENTAL RESEARCH

The Allen Brain Atlas: 5 years and beyond

(2009) Allan R. Jones et al.   NATURE REVIEWS NEUROSCIENCE

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Regulation of Clock-Controlled Genes in Mammals

(2009) Katarzyna Bozek et al.   PLoS One

Oxygen homeostasis

(2009) Gregg L. Semenza   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Acute and chronic hypoxia affects HIF-1α mRNA levels in sea bass (Dicentrarchus labrax)

(2008) Genciana Terova et al.   AQUACULTURE

Hypoxia alters gene expression in the gonads of zebrafish (Danio rerio)☆☆☆◊

(2008) Dalma Martinovic et al.   AQUATIC TOXICOLOGY

Turn me on: regulating HIF transcriptional activity

(2008) K Lisy et al.   CELL DEATH AND DIFFERENTIATION

Biology of hypoxia-inducible factor-2α in development and disease

(2008) S A Patel et al.   CELL DEATH AND DIFFERENTIATION

Variable patterns in the molecular evolution of the hypoxia-inducible factor-1 alpha (HIF-1α) gene in teleost fishes and mammals

(2008) Kalle T. Rytkönen et al.   GENE

The effect of hypoxia on gill morphology and ionoregulatory status in the Lake Qinghai scaleless carp, Gymnocypris przewalskii

(2008) V. Matey et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons

(2008) Shengjun Chang et al.   NEUROSCIENCE LETTERS

Spreading Dead Zones and Consequences for Marine Ecosystems

(2008) R. J. Diaz et al.   SCIENCE