Article
Medicine, Research & Experimental
Jie Zhu, Ling Han, Ruilai Liu, Zhenghua Zhang, Qiong Huang, Xu Fang, Ke Yang, Guiqin Huang, Zhizhong Zheng, Nikhil Yawalkar, Hui Deng, Kexiang Yan
Summary: By analyzing the proteome profile of PBMCs from patients with PsA, PsO, and healthy controls, this study identified 14 potential biomarkers for PsA diagnosis. Additionally, the expression of SIRT2 was significantly higher in PsA patients compared to PsO and healthy controls, and was negatively correlated with the phosphorylation of p38MAPK.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Xinyang Li, Xueqian Zhang, Wenna Yang, Lanping Guo, Luqi Huang, Xia Li, Wenyuan Gao
Summary: This study compared the structural and physicochemical properties of native Banxia starch and autoclaving-cooling treated Banxia starch, finding that the CTBXS showed better thermal stability and higher SDS content. Both types of starch were able to change the composition of gut microbiota and promote the production of SCFAs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Organic
Ming-Ling Wang, Rong Chen, Fu-Juan Sun, Peng-Ran Cao, Xing-Ru Chen, Ming-Hua Yang
Summary: Three new indole diketopiperazine alkaloids, aspergillines A-C (1-3), and one new polyketide, aspergillone A (4), were isolated from the solid cultures of an endophytic fungus Aspergillus cristatus. Aspergilline A is the first bicyclo[2.2.2] diazaoctane indole alkaloid constructed from tryptophan and alanine. Aspergillone A exhibited moderate antibacterial activities against Bacillus subtilis and Staphylococcus aureus.
TETRAHEDRON LETTERS
(2021)
Article
Plant Sciences
Liang Gu, Fu-Juan Sun, Cui-Ping Li, Le-Tian Cui, Ming-Hua Yang, Ling-Yi Kong
Summary: A new alkaloid and a dimeric derivative of citrinin were isolated from the solid culture of an endophytic Aspergillus terreus residing in Pinellia ternata. Penicitrinol Q showed inhibitory effects against Staphylococcus aureus and Bacillus subtilis, while compound 2 exhibited enhanced susceptibility to doxorubicin in treating doxorubicin-resistant human breast cancer cells.
PHYTOCHEMISTRY LETTERS
(2021)
Article
Agriculture, Dairy & Animal Science
Muhan Zhang, Daoying Wang, Xinglian Xu, Weimin Xu, Guanghong Zhou
Summary: The study identified 301 differentially expressed proteins in duck muscles related to lipid oxidation through iTRAQ analysis and confirmed by PRM. These proteins were found to be involved in lipid binding and metabolism, lipolysis, stress response, oxidative respiratory chain, and redox regulation, potentially impacting lipid oxidation in muscles.
Article
Multidisciplinary Sciences
Lifen Meng, Zhi Xia, Jingsong Lv, Gaofu Liu, Ye Tan, Qianzhu Li
Summary: This paper determined the strong allelopathy of five phenolic acids in the rhizosphere soil of Pinellia ternate to Pinellia ternate. The content changes of these phenolic acids were analyzed by comparing their contents in the rhizosphere soil before, during and after planting. The results showed that the five phenolic acids have inhib-itory effects on the growth of Pinellia ternate.
JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Xin Ma, Meng Wang, Jinglei Wang, Qian Zhang, Sisi Pu, Rui Wang, Sijiu Yu, Libin Wang, Yangyang Pan
Summary: In this study, the dynamic changes in yak oocytes during maturation were analyzed using iTRAQ technology. Differential proteomics sequencing revealed transient dynamic changes in the proteome and differences in physiological functions at different stages of oocyte maturation. Accurate identification of the differential proteins provides insights into the molecular regulatory mechanism of yak oocyte maturation.
Article
Microbiology
Yifan Fu, Qinggang Guo, Lihong Dong, Xiaomeng Liu, Xiuye Chen, Peipei Wang, Zhenhe Su, Ping Ma
Summary: This study characterizes the regulatory mechanism of the PhoPR two-component system (TCS) in Bacillus subtilis, showing its role in the regulation of fengycin production through the biosynthesis of branched chain amino acids (BCAAs). These findings provide insights into the signaling pathway involved in the phosphate starvation response and the production of antibiotics in bacteria.
MICROBIOLOGICAL RESEARCH
(2022)
Article
Agriculture, Multidisciplinary
Xue Luo, Mo Li, Henan Zhang, Danli Yan, Shuaiqi Ji, Rina Wu, Yongfu Chen
Summary: Proteomics and bioinformatics analysis of three strains of Lactobacillus plantarum under salt stress revealed differential expression of proteins related to protein biosynthesis, nucleotide metabolism, and sugar metabolism. Specific differentially expressed proteins were found between the strains in response to high salt conditions.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biochemistry & Molecular Biology
Heng Wee Tan, Yan-Ming Xu, Zhan-Ling Liang, Na-Li Cai, Yu-Yao Wu, Andy T. Y. Lau
Summary: This study explores the proteomic landscape of cells with impaired ZIP8 and uncovers the potential relationships between essential micronutrients and uncharacterized proteins C9orf85 and CXorf38. The differentially expressed proteins identified in ZIP8-KO cells could be potential targets for diagnosing and/or treating human ZIP8-associated diseases, including but not limited to malnutrition, viral infection, and cancers.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Agronomy
Xiaoli Zhang, Maoyan Tang, Hui Wang, Wei Tao, Qiang Wang, Lei Chen, Guoqing Gao, Ronghua Lv, Tianfeng Liang
Summary: This study found that the Southeast Asian germplasm resource C1 has a higher photosynthetic efficiency compared to G164, as evidenced by better tissue structure, chloroplast ultrastructure, and photosynthetic physiological indicators. Proteomics analysis also revealed higher activity of key photosynthetic enzymes in C1. These findings provide an important foundation for breeding high light efficiency varieties and further understanding photosynthesis.
Article
Plant Sciences
Yong Gao, Xia Shi, Yongyuan Chang, Yingbo Li, Xuehang Xiong, Hongmei Liu, Mengyuan Li, Weihua Li, Xuehai Zhang, Zhiyuan Fu, Yadong Xue, Jihua Tang
Summary: Narrowing down a single putative target gene and constructing the regulation network by proteomic method for a leaf senescence mutant. Leaf senescence mutant is an important resource for exploring molecular mechanism of aging. Proteomics analysis of the mutant and its wild type revealed differentially accumulated proteins mainly enriched in regulation pathways such as photosynthesis, ribosome, and chlorophyll metabolism. The interaction networks constructed by transcriptome data showed that ZmELS5 likely repaired several key factors in the photosynthesis system. These results provide a fundamental basis and new insights for further research on the molecular mechanism of leaf senescence in maize.
PLANT CELL REPORTS
(2023)
Article
Agriculture, Dairy & Animal Science
Mingxing Cao, Lin Huang, Suyu Jin, Mengbo Zhao, Yucai Zheng
Summary: The study compared the milk protein compositions of standard lactation and prolonged lactation yaks using iTRAQ technique, revealing degeneration characteristics in the milk proteins of prolonged lactation yaks. Metabolic pathway differences were mainly centered around carbohydrate metabolism and amino acid biosynthesis pathways.
Article
Plant Sciences
Jialiang Li, Rui Yang, Yonglei Jiang, Shubin Sun, Junying Li, Hao Gu, Ying Lin, Xianxue Luo, Chenggang He, Yi Chen
Summary: This study provides insights into the responses of tobacco roots to different soil types, showing that red soil promotes the coordination of chemical composition of tobacco leaves and the growth and activity of the root system, while limestone soil and paddy soil have relatively weaker effects.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Reproductive Biology
Xiangping Li, JiaHui Yao, Jiaying Hu, ChunHua Deng, Yun Xie, Zhu Wang
Summary: This study identified 1477 proteins in murine TIF, with 706 proteins showing a linear change trend with age and 45 age-related DEPs identified. Bioinformatic analyses revealed that these proteins were involved in actin cytoskeleton organization, intrinsic apoptotic signaling pathway, and regulation of protein transport. Comparative analysis with relevant proteomes further revealed the characteristics of mouse TIF proteome.
Article
Food Science & Technology
Chang-Yu Zhou, Chong Wang, Chen Dai, Yun Bai, Xiao-Bo Yu, Chun-Bao Li, Xing-Lian Xu, Guang-Hong Zhou, Jin-Xuan Cao
Article
Chemistry, Applied
Chang-Yu Zhou, Chong Wang, Chang-Bo Tang, Chen Dai, Yun Bai, Xiao-Bo Yu, Chun-Bao Li, Xing-Lian Xu, Guang-Hong Zhou, Jin-Xuan Cao
Article
Chemistry, Applied
Chong Wang, Yunting Xie, Huiyuan Wang, Yun Bai, Chen Dai, Chunbao Li, Xinglian Xu, Guanghong Zhou
Article
Plant Sciences
Weiti Cui, Ping Yao, Jincheng Pan, Chen Dai, Hong Cao, Zhiyu Chen, Shiting Zhang, Sheng Xu, Wenbiao Shen
Article
Biotechnology & Applied Microbiology
Long Zhang, Ping Hang, Xiyi Zhou, Chen Dai, Ziyi He, Jiandong Jiang
MICROBIAL CELL FACTORIES
(2020)
Article
Chemistry, Applied
Chang-Yu Zhou, Chang-Bo Tang, Chong Wang, Chen Dai, Yun Bai, Xiao-Bo Yu, Chun-Bao Li, Xing-Lian Xu, Guang-Hong Zhou, Jin-Xuan Cao
Article
Nutrition & Dietetics
Xiaoyu Zou, Jing He, Di Zhao, Min Zhang, Yunting Xie, Chen Dai, Chong Wang, Chunbao Li
FRONTIERS IN NUTRITION
(2020)
Article
Biotechnology & Applied Microbiology
Youzhou Liu, Chen Dai, Yaqiu Zhou, Junqing Qiao, Bao Tang, Wenjie Yu, Rongshen Zhang, Yongfeng Liu, Shi-En Lu
Summary: The study showed that PVDs are crucial for the broad-spectrum antibacterial activities of strain YL-1 against both Gram-positive and Gram-negative bacteria under low-iron conditions. The findings also emphasize the impact of exogenous iron on PVD production and the significance of this bacterial product in bacterial interactions.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Chemistry, Analytical
Zhiwei Miao, Kang Ding, Shuyin Jin, Lin Dai, Chen Dai, Xiang Li
Summary: The study utilized peptidomics to identify serum diagnostic markers for different stages of ulcerative colitis (UC), involving the identification of 40 peptides and the screening of six biomarker peptides derived from proteins associated with coagulation and complement activation. The perturbation of these peptides was found to effectively distinguish patients with active UC, patients with remitting UC, and healthy individuals, demonstrating the potential of serum peptidomics in diagnosing various stages of UC.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Food Science & Technology
Chen Dai, Lin Dai, Feng-Jie Yu, Xi-Nuo Li, Guo-Xiang Wang, Jun Chen, Chong Wang, Ya-Ping Lu
JOURNAL OF FUNCTIONAL FOODS
(2020)
Article
Biochemistry & Molecular Biology
Chen Dai, Shuang Wang, Cristabelle De Souza, You-Ying Li, Chuang Zhou, Reng Qiu, Xiao-Zhou Xu, Hong-Lei Zhou, Yi Wu
Summary: The phytochemical study of Glycyrrhiza pallidiflora Maxim revealed seventeen compounds, indicating a close relationship with other species of Glycyrrhiza. Specific compounds like pallidiflorin, macedonic acid, and echinatin serve as fingerprint or biomarkers for identifying Glycyrrhiza species.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Jinjiao Zuo, Yanan Cao, Zhisheng Wang, Abid Ullah Shah, Wenlei Wang, Chen Dai, Mingjia Chen, Jian Lin, Qian Yang
Summary: IBV inhibits the antigen-presentation ability of avian dendritic cells by suppressing their maturation, cytokine secretion, and antigen presentation.
Article
Plant Sciences
Yihua Zhang, Pengfei Cheng, Jun Wang, Dyaaaldin Abdalmegeed, Ying Li, Mangteng Wu, Chen Dai, Shubei Wan, Rongzhan Guan, Huiming Pu, Wenbiao Shen
Summary: Heterosis was observed in Brassica napus L. hybrid under salt stress, with better redox and ion balance compared to parental lines. Increased endogenous NO levels and suppressed protein abundance related to metabolic processes were key factors contributing to heterosis in hybrid plants under salt stress conditions. The study suggests that NO-dependent activation of defense responses and metabolic processes may mediate heterosis in F1 hybridization for salt stress tolerance.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Analytical
Yiting Shi, Fengjie Yu, Yi Wu, Lin Dai, Yutong Feng, Shilei Chen, Guoxiang Wang, Hongyu Ma, Xitong Li, Chen Dai
Summary: The study identified GLpGER as a potential bioactive peptide derived from natural proteins that may help reduce acute alcohol-induced liver injury by restoring liver ADH activity and decreasing alcohol concentration levels.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Agronomy
Donglu Fang, Zimeng Zheng, Ning Ma, Wenjian Yang, Chen Dai, Mingwen Zhao, Zilong Deng, Qiuhui Hu, Liyan Zhao
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2020)
Correction
Plant Sciences
Lingmiao Wen, Tinglan Zhang, Fangfang Chen, Lin Hu, Chongyang Dou, Xian Ding, Alvin Altamirano, Guihua Wei, Zhiyong Yan
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Qing Tang, Mengfei Xu, Shunqin Long, Yaya Yu, Changju Ma, Rui Wang, Jing Li, Xi Wang, Fang Fang, Ling Han, Wanyin Wu, Sumei Wang
Summary: This study demonstrates that Fuzheng Kang-Ai (FZKA) decoction can inhibit the cell growth, proliferation, and invasion of lung adenocarcinoma (LUAD) and reverse the acquired resistance of gefitinib. FZKA exerts its effects by regulating the p-ERK1/2-EZH2-Snail/EGFR signaling pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Xiang Zhao, Xianrun Hu, Qi Xie, Shenglan Qi, Zedong Xiang, Xin Sun, Zhejun Xie, Rui Dang, Limei Zhou, Wei Liu, Xuemei Cheng, Changhong Wang
Summary: This study investigated the effects of Fufangmuniziqi formula (FFMN) on Alzheimer's disease (AD) and the role of alkaloids, flavonoids, and saponins in the process. The results showed that FFMN improved cognitive and memory impairment in the AD mouse model. Alkaloids enhanced the cholinergic system, while flavonoids and saponins attenuated neuroinflammation and oxidative stress. These findings suggest that the combination of alkaloid, flavonoid, and saponin fractions derived from FFMN is a promising anti-AD agent.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Bangjian Dong, Ying Peng, Mengyue Wang, Chongsheng Peng, Xiaobo Li
Summary: This study elucidated the tissue distribution and excretion characteristics of the non-polysaccharide components of Sijunzi decoction in rats with spleen deficiency syndrome. It proposed new insights into the rationality of the compatibility of Sijunzi decoction.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jung-Seop Kim, Man-Gi Kim, Ji Eun Ryu, Ye-Been Lee, Quan Feng Liu, Kwang Ki Kim, Seung-Hun Cho, Sung Joon Shin, Byung-Soo Koo, Hyung-Kyoon Choi
Summary: Co-treatment with WCW and donepezil shows promise in improving cognitive function and serum metabolic profiles in a scopolamine-induced AD model. This combination therapy may reduce tyrosine and methionine levels, enhancing cognitive function by mitigating known risk factors for AD. The study provides a foundation for developing other bioactive compounds in AD treatment.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Kuang-Hsing Chiang, Tain-Junn Cheng, Wei-Chih Kan, Hsien-Yi Wang, Jui-Chen Li, Yan-Ling Cai, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu
Summary: The ethanolic extract of Orthosiphon aristatus (OA) demonstrated an improving effect on memory and could serve as a potential therapeutic target for the treatment of neurodegenerative diseases like Alzheimer's disease (AD).
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Meryem Tourabi, Asmae EL Ghouizi, Ghizlane Nouioura, Khaoula Faiz, Hind Elfatemi, Karima El-yagoubi, Badiaa Lyoussi, Elhoussine Derwich
Summary: Mentha longifolia is a native plant in Morocco, traditionally used to treat various diseases. This study analyzed the phytochemical profile of the aqueous extract of M. longifolia and evaluated its acute and subacute toxicity in mice. The results showed that M. longifolia extract is rich in phenolic compounds and has no observed toxicity up to a certain dosage limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-yan Du, Yan Jiang
Summary: Mulberry leaf multi-components (MMC) have hypoglycemic effects and can improve insulin resistance by activating the PI-3K/Akt signaling pathway. These findings highlight the multi-component, multi-target, and combined effects of MMC, and suggest it may be further developed as a hypoglycemic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Correction
Plant Sciences
Shan Luo, Yuanchun Chen, Ruoxi Zhao, Donglai Ma, Yanmeng Zhao, Ying Zhang, Jianming Jiang, Wentao Yu
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Nittaya Chansiw, Pattranuch Chusri, Siwaporn Praman, Thaneeya Hawiset, Wannisa Sukhorum, Sorraya Champakam, Rawiwan Charoensup
Summary: This study evaluates the anti-inflammatory activity of Prabchompoothaweep (PCT) extract in an animal model. The results show that PCT significantly reduces inflammation and pro-inflammatory cytokines in acute and sub-acute inflammation. These findings suggest that PCT could be a new option for the treatment of inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu
Summary: Bushen Tianjing Recipe (BTR) is a tonic-kidney formula of Traditional Chinese Medicine (TCM) with good therapeutic effects in clinical settings. The aim of this study was to investigate the effect of BTR on women's reproductive system by incubating miR-23a-induced KGN cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jiayi Zhi, Li Yin, Zhoudong Zhang, Yaozhong Lv, Fan Wu, Yang Yang, Enming Zhang, Huanqiu Li, Ning Lu, Mengze Zhou, Qinghua Hu
Summary: This study verified the pharmacodynamics of JSW in the treatment of AD and explored its potential mechanism using network pharmacology, molecular docking, and experimental validation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Review
Plant Sciences
Elizabeth Syowai Mutinda, Dong-Juan Zhang, Felix Wambua Muema, Elijah Mbandi Mkala, Emmanuel Nyongesa Waswa, Wyclif Ochieng Odago, Clintone Onyango Ochieng, Moses Kirega Gichua, John Kamau Muchuku, Elizabeth Kamande, Guang-Wan Hu
Summary: This article reviews the traditional uses, pharmacological properties, and phytoconstituents of Balanophora species, revealing that they contain diverse chemical compounds with interesting biological activities. However, research on many species in this genus is still lacking.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Luqi Cai, Yu Chen, Huizhong Xue, Yimeng Yang, Yuqi Wang, Junhe Xu, Chunyan Zhu, Long He, Yonghua Xiao
Summary: Salvia miltiorrhiza Bunge (SM) has been proven to have potential therapeutic effects for diabetic nephropathy (DN) through its multi-component, multi-target, and multi-pathway pharmacological effects.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Chao Wang, Rui-Jia Fu, Ding-Qiao Xu, Qian Zuo, Ji-Ping Liu, Yu-Ping Tang
Summary: This study aimed to explore the hepatoprotective effects of Shicao on CCl4-induced acute liver injury. A rat model of acute liver injury was established and liver function indices were assessed. Untargeted metabolomics was conducted to identify differential metabolites. Network pharmacology was used to construct a network of metabolite-reaction-enzyme-gene constituents, and key components and hub genes were screened. Shicao showed hepatoprotective effects against acute liver injury in rats.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)