Targeting the death receptor signaling pathway as a potential therapeutic target in the treatment of colorectal cancer
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Title
Targeting the death receptor signaling pathway as a potential therapeutic target in the treatment of colorectal cancer
Authors
Keywords
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Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume 233, Issue 10, Pages 6538-6549
Publisher
Wiley
Online
2018-05-10
DOI
10.1002/jcp.26640
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Note: Only part of the references are listed.- Stem Cells in Repair of Gastrointestinal Epithelia
- (2017) Amanda Andersson-Rolf et al. PHYSIOLOGY
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- Fas/Fas-Ligand Interaction As a Mechanism of Immune Homeostasis and β-Cell Cytotoxicity: Enforcement Rather Than Neutralization for Treatment of Type 1 Diabetes
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- (2017) A. D. Baron et al. JOURNAL OF CLINICAL ONCOLOGY
- Global patterns and trends in colorectal cancer incidence and mortality
- (2016) Melina Arnold et al. GUT
- Vascular-targeted TNFα and IFNγ inhibits orthotopic colorectal tumor growth
- (2016) Jing Shen et al. Journal of Translational Medicine
- Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer
- (2016) Marina Devetzi et al. Scientific Reports
- Colorectal Cancer Heterogeneity and Targeted Therapy: A Case for Molecular Disease Subtypes
- (2015) J. F. Linnekamp et al. CANCER RESEARCH
- The role of CD95 and CD95 ligand in cancer
- (2015) M E Peter et al. CELL DEATH AND DIFFERENTIATION
- TNFerade, an innovative cancer immunotherapeutic
- (2015) Arunava Kali INDIAN JOURNAL OF PHARMACOLOGY
- Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer
- (2015) Marika Ciprotti et al. JOURNAL OF CLINICAL ONCOLOGY
- Vascular-targeted TNFα improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer
- (2015) Lan Lu et al. JOURNAL OF CONTROLLED RELEASE
- H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance
- (2015) Amy V. Paschall et al. JOURNAL OF IMMUNOLOGY
- Therapeutic applications of TRAIL receptor agonists in cancer and beyond
- (2015) Gustavo P. Amarante-Mendes et al. PHARMACOLOGY & THERAPEUTICS
- DED or alive: assembly and regulation of the death effector domain complexes
- (2015) J S Riley et al. Cell Death & Disease
- Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen
- (2015) Boya Zhong et al. Journal of Immunology Research
- The CD95/CD95L signaling pathway: A role in carcinogenesis
- (2014) Amélie Fouqué et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer
- (2014) Rui Yu et al. CANCER BIOLOGY & THERAPY
- Armed antibodies for cancer treatment: a promising tool in a changing era
- (2014) Riccardo Danielli et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- True Grit: Programmed Necrosis in Antiviral Host Defense, Inflammation, and Immunogenicity
- (2014) E. S. Mocarski et al. JOURNAL OF IMMUNOLOGY
- EGFR-Targeted TRAIL and a Smac Mimetic Synergize to Overcome Apoptosis Resistance in KRAS Mutant Colorectal Cancer Cells
- (2014) Yvonne Möller et al. PLoS One
- Necroptotic signaling in adaptive and innate immunity
- (2014) Jennifer V. Lu et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Targeting cell death signaling in colorectal cancer: Current strategies and future perspectives
- (2014) Bruno Christian Koehler WORLD JOURNAL OF GASTROENTEROLOGY
- A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer†
- (2013) A. L. Cohn et al. ANNALS OF ONCOLOGY
- The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity
- (2013) T Hemmerle et al. BRITISH JOURNAL OF CANCER
- TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first-line treatment of metastatic colorectal cancer
- (2013) Charles S. Fuchs et al. CANCER
- Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis
- (2013) D Westphal et al. CELL DEATH AND DIFFERENTIATION
- Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
- (2013) I. J. G. Burvenich et al. CLINICAL CANCER RESEARCH
- A Phase 1B Study of Dulanermin in Combination With Modified FOLFOX6 Plus Bevacizumab in Patients With Metastatic Colorectal Cancer
- (2013) Zev A. Wainberg et al. Clinical Colorectal Cancer
- Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors
- (2013) Sunil Sharma et al. INVESTIGATIONAL NEW DRUGS
- Randomized Phase III Multi-Institutional Study of TNFerade Biologic With Fluorouracil and Radiotherapy for Locally Advanced Pancreatic Cancer: Final Results
- (2013) Joseph M. Herman et al. JOURNAL OF CLINICAL ONCOLOGY
- Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling
- (2013) Tamas Sessler et al. PHARMACOLOGY & THERAPEUTICS
- Death Receptor-Ligand Systems in Cancer, Cell Death, and Inflammation
- (2013) H. Walczak Cold Spring Harbor Perspectives in Biology
- Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells
- (2013) X Song et al. Cell Death & Disease
- CD95 signaling in colorectal cancer
- (2012) Frederik J.H. Hoogwater et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Sensitization of (colon) cancer cells to death receptor related therapies
- (2012) Alexander Pintzas et al. CANCER BIOLOGY & THERAPY
- Phase Ib Study of Drozitumab Combined With First-Line mFOLFOX6 Plus Bevacizumab in Patients with Metastatic Colorectal Cancer
- (2012) Caio M. Rocha Lima et al. CANCER INVESTIGATION
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- (2012) Kristin Wahl et al. HEPATOLOGY
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- (2012) Jochen Tuettenberg et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Molecular Targets of TRAIL-Sensitizing Agents in Colorectal Cancer
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- Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells
- (2011) Henriette Kauntz et al. APOPTOSIS
- Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins
- (2011) Vivek R Yadav et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2011) Eftychia Oikonomou et al. PLoS One
- Exploring death receptor pathways as selective targets in cancer therapy
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- Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
- (2010) T Trarbach et al. BRITISH JOURNAL OF CANCER
- Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types
- (2010) Paula J. Kaplan-Lefko et al. CANCER BIOLOGY & THERAPY
- Phase I Trial of Weekly Tigatuzumab, an Agonistic Humanized Monoclonal Antibody Targeting Death Receptor 5 (DR5)
- (2010) Andres Forero-Torres et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells
- (2010) C. Lepage et al. CANCER LETTERS
- BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane
- (2010) Z T Schug et al. CELL DEATH AND DIFFERENTIATION
- A First-in-Human Study of Conatumumab in Adult Patients with Advanced Solid Tumors
- (2010) R. S. Herbst et al. CLINICAL CANCER RESEARCH
- Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy
- (2010) Armando Santoro et al. EUROPEAN JOURNAL OF CANCER
- CD95 is cytoprotective for intestinal epithelial cells in colitis
- (2010) Sun-Mi Park et al. INFLAMMATORY BOWEL DISEASES
- Cell death in the colonic epithelium during inflammatory bowel diseases
- (2010) Lina Chen et al. INFLAMMATORY BOWEL DISEASES
- Targeting a Novel N-terminal Epitope of Death Receptor 5 Triggers Tumor Cell Death
- (2010) Peng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
- (2010) Toshiro Sato et al. NATURE
- Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers
- (2009) R R Weichselbaum et al. CANCER GENE THERAPY
- Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells
- (2009) Takeshi Hori et al. CANCER LETTERS
- Death receptors: Targets for cancer therapy
- (2009) Zafar Mahmood et al. EXPERIMENTAL CELL RESEARCH
- XIAP discriminates between type I and type II FAS-induced apoptosis
- (2009) Philipp J. Jost et al. NATURE
- A novel humanized anti-human death receptor 5 antibody CS-1008 induces apoptosis in tumor cells without toxicity in hepatocytes
- (2008) A. Yada et al. ANNALS OF ONCOLOGY
- Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis
- (2008) Tatsushi Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Baicalein Overcomes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance via Two Different Cell-Specific Pathways in Cancer Cells but not in Normal Cells
- (2008) Hiroya Taniguchi et al. CANCER RESEARCH
- DR4-selective Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Variants Obtained by Structure-based Design
- (2008) Vicente Tur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 15-deoxy-Δ12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription
- (2008) Rong-Ying Su et al. MOLECULAR CANCER THERAPEUTICS
- Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole
- (2008) A E Goda et al. ONCOGENE
- Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
- (2008) Tatsushi Yoshida et al. Environmental Health and Preventive Medicine
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