Brain-derived neurotrophic factor modulates cholesterol homeostasis and Apolipoprotein E synthesis in human cell models of astrocytes and neurons

ApoE isoforms differentially regulates cleavage and secretion of BDNF

(2017) Abhik Sen et al.   Molecular Brain

Liver X receptors: from cholesterol regulation to neuroprotection—a new barrier against neurodegeneration in amyotrophic lateral sclerosis?

(2016) Kevin Mouzat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Can Cholesterol Metabolism Modulation Affect Brain Function and Behavior?

(2016) Veronica Cartocci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling

(2016) Yen-Ning Huang et al.   NEUROSCIENCE

LXR Regulation of Brain Cholesterol: From Development to Disease

(2016) Rebecca Courtney et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Long Non-coding RNA in Neurons: New Players in Early Response to BDNF Stimulation

(2016) Vincenza Aliperti et al.   Frontiers in Molecular Neuroscience

BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes

(2015) Rita I. Aroeira et al.   GLIA

High Fat Diet and Inflammation – Modulation of Haptoglobin Level in Rat Brain

(2015) Maria Stefania Spagnuolo et al.   Frontiers in Cellular Neuroscience

Haptoglobin Interacts with Apolipoprotein E and Beta-Amyloid and Influences Their Crosstalk

(2014) Maria Stefania Spagnuolo et al.   ACS Chemical Neuroscience

HDL and cholesterol handling in the brain

(2014) C. Vitali et al.   CARDIOVASCULAR RESEARCH

Haptoglobin Modulates Beta-Amyloid Uptake by U-87 MG Astrocyte Cell Line

(2014) Bernardetta Maresca et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

More than Cholesterol Transporters: Lipoprotein Receptors in CNS Function and Neurodegeneration

(2014) Courtney Lane-Donovan et al.   NEURON

Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines

(2014) Maria Stefania Spagnuolo et al.   Frontiers in Cellular Neuroscience

TrkB Receptor Signalling: Implications in Neurodegenerative, Psychiatric and Proliferative Disorders

(2013) Vivek Gupta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells

(2013) Vishwaroop Mulay et al.   PLoS One

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

(2012) J. E. Vance   Disease Models & Mechanisms

Hyperglycemia accelerates ATP-binding cassette transporter A1 degradation via an ERK-dependent pathway in macrophages

(2012) Yu-Cheng Chang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mechanical injured neurons stimulate astrocytes to express apolipoprotein E through ERK pathway

(2012) Cheng Yin et al.   NEUROSCIENCE LETTERS

Lipid raft: A floating island of death or survival

(2012) Kimberly S. George et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

ApoE is required for maintenance of the dentate gyrus neural progenitor pool

(2011) C.-P. Yang et al.   DEVELOPMENT

Brain-derived Neurotrophic Factor (BDNF) Enhances GABA Transport by Modulating the Trafficking of GABA Transporter-1 (GAT-1) from the Plasma Membrane of Rat Cortical Astrocytes

(2011) Sandra H. Vaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol metabolism in neurons and astrocytes

(2011) Frank W. Pfrieger et al.   PROGRESS IN LIPID RESEARCH

Lipids in Alzheimer's disease: A century-old story

(2010) Paul Foley   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Formation and function of apolipoprotein E-containing lipoproteins in the nervous system

(2010) Jean E. Vance et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cholesterol changes in Alzheimer's disease: methods of analysis and impact on the formation of enlarged endosomes

(2010) Jack-Christophe Cossec et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways

(2010) Eun-Ra Jang et al.   NEUROCHEMISTRY INTERNATIONAL

Apolipoprotein E receptors in the nervous system

(2009) Joachim Herz   CURRENT OPINION IN LIPIDOLOGY

Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases☆

(2009) Sinéad Lordan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cholesterol involvement in the pathogenesis of neurodegenerative diseases

(2009) Jun-Ping Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis

(2009) Anne Vejux et al.   MOLECULAR ASPECTS OF MEDICINE

Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis

(2008) A. Vejux et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The Biology of Neurotrophins, Signalling Pathways, and Functional Peptide Mimetics of Neurotrophins and their Receptors

(2008) Stephen Skaper   CNS & Neurological Disorders-Drug Targets

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY