High Fat Diet and Inflammation – Modulation of Haptoglobin Level in Rat Brain

Cognitive Function and Decline in Obesity

(2018) Kelly Stanek Sellbom et al.   JOURNAL OF ALZHEIMERS DISEASE

Peroxynitrite decomposition catalyst prevents matrix metalloproteinase-9 activation and neurovascular injury after hemoglobin injection into the caudate nucleus of rats

(2015) R. Ding et al.   NEUROSCIENCE

Haptoglobin Interacts with Apolipoprotein E and Beta-Amyloid and Influences Their Crosstalk

(2014) Maria Stefania Spagnuolo et al.   ACS Chemical Neuroscience

Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage

(2014) Yan-Chun Wang et al.   ANNALS OF NEUROLOGY

Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation

(2014) Rui Ding et al.   BRAIN RESEARCH

Obesity-Induced Cerebral Hypoperfusion Derived from Endothelial Dysfunction: One of the Risk Factors for Alzheimer’s Disease

(2014) Noboru Toda et al.   Current Alzheimer Research

Haptoglobin Modulates Beta-Amyloid Uptake by U-87 MG Astrocyte Cell Line

(2014) Bernardetta Maresca et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells

(2014) Valeria La Marca et al.   JOURNAL OF NEUROCHEMISTRY

Mass spectrometric analysis of protein tyrosine nitration in aging and neurodegenerative diseases

(2014) Woon-Seok Yeo et al.   MASS SPECTROMETRY REVIEWS

Early endothelial nitrosylation and increased abdominal adiposity in Wistar rats after long-term consumption of food fried in canola oil

(2014) Rocío Bautista et al.   NUTRITION

Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines

(2014) Maria Stefania Spagnuolo et al.   Frontiers in Cellular Neuroscience

Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

(2014) Ted M. Hsu et al.   Frontiers in Aging Neuroscience

The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders

(2014) Pamela J. Urrutia et al.   Frontiers in Pharmacology

Obesity and impaired cognitive functioning in the elderly: a population-based cross-sectional study (NEDICES)

(2013) J. Benito-León et al.   EUROPEAN JOURNAL OF NEUROLOGY

Hemoglobin-Induced Nitric Oxide Synthase Overexpression and Nitric Oxide Production Contribute to Blood–Brain Barrier Disruption in the Rat

(2013) Shuo Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Damaging effects of a high-fat diet to the brain and cognition: A review of proposed mechanisms

(2013) Linnea R. Freeman et al.   NUTRITIONAL NEUROSCIENCE

Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

(2012) Xiaoke Wang et al.   Experimental Diabetes Research

Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics

(2012) A. Cocciolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease

(2012) Jia-Ying Chuang et al.   PLoS One

Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency

(2011) S. Lisi et al.   DIABETES

Do extracellular chaperone proteins in plasma have potential as Alzheimer’s disease biomarkers?

(2010) Madhav Thambisetty   Biomarkers in Medicine

Hemoglobin-Induced Oxidative Stress Contributes to Matrix Metalloproteinase Activation and Blood–Brain Barrier Dysfunction in vivo

(2010) Masataka Katsu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

(2009) Suzanne Craft   ARCHIVES OF NEUROLOGY

Role of protein tyrosine nitration in neurodegenerative diseases and atherosclerosis

(2009) Jung Rok Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Extracellular chaperones modulate the effects of Alzheimer’s patient cerebrospinal fluid on Aβ1-42 toxicity and uptake

(2009) Justin J. Yerbury et al.   CELL STRESS & CHAPERONES

Haptoglobin binds the antiatherogenic protein apolipoprotein E - impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes

(2009) Luisa Cigliano et al.   FEBS Journal

Neurons express hemoglobin α- and β-chains in rat and human brains

(2009) Franziska Richter et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Haptoglobin binds apolipoprotein E and influences cholesterol esterification in the cerebrospinal Fluid

(2009) Alfonso Salvatore et al.   JOURNAL OF NEUROCHEMISTRY

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuroprotective Role of Haptoglobin after Intracerebral Hemorrhage

(2009) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet

(2009) Christy L. White et al.   NEUROBIOLOGY OF DISEASE

Unexpected expression of  - and  -globin in mesencephalic dopaminergic neurons and glial cells

(2009) M. Biagioli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebroprotective Functions of HO-2

(2008) Helena Parfenova et al.   CURRENT PHARMACEUTICAL DESIGN

A life course of adiposity and dementia

(2008) Deborah Gustafson   EUROPEAN JOURNAL OF PHARMACOLOGY

α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species

(2008) Justin J. Yerbury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Hemoglobin in Rodent Neurons

(2008) Dominik W Schelshorn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice

(2008) Lakshmi Thirumangalakudi et al.   JOURNAL OF NEUROCHEMISTRY

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

Haptoglobin, inflammation and disease

(2008) Isaac K. Quaye   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity

(2007) Mark R. Wilson et al.   Molecular BioSystems