H3 relaxin inhibits the collagen synthesis via ROS- and P2X7R-mediated NLRP3 inflammasome activation in cardiac fibroblasts under high glucose

Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis

(2017) Wen-Xia Pi et al.   MOLECULES

Neuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in mice

(2017) Frances M. Munoz et al.   Scientific Reports

Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus

(2016) Surya Ramachandran et al.   Cardiovascular Diabetology

CD40 in Retinal Müller Cells Induces P2X 7 -Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy

(2016) Jose-Andres C. Portillo et al.   DIABETES

Orthostatic hypotension in diabetic patients—10-year follow-up study

(2016) Ludovit Gaspar et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice

(2016) Flávia Sarmento Vieira et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

miR-9 Mediates CALHM1-Activated ATP-P2X7R Signal in Painful Diabetic Neuropathy Rats

(2016) Wenjie Liu et al.   MOLECULAR NEUROBIOLOGY

Renal vasculature reactivity to agonist of P2X7 receptor is increased in streptozotocin-induced diabetes

(2016) Ewelina Kreft et al.   Pharmacological Reports

P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

(2016) Zeynep Seref-Ferlengez et al.   PLoS One

H2 and H3 relaxin inhibit high glucose-induced apoptosis in neonatal rat ventricular myocytes

(2015) Xiaohui Zhang et al.   BIOCHIMIE

Correlation between advanced glycation end-products and the expression of fatty inflammatory factors in type II diabetic cardiomyopathy

(2015) Zhengdong Guo et al.   Bosnian Journal of Basic Medical Sciences

Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

(2015) Zhongwei Liu et al.   Cardiovascular Diabetology

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

(2015) KUANG PENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Bisphosphonate Induces Osteonecrosis of the Jaw in Diabetic Mice via NLRP3/Caspase-1-Dependent IL-1β Mechanism

(2015) Qunzhou Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

(2015) Liang Feng et al.   Journal of Neuroinflammation

Inflammasomes: Molecular Regulation and Implications for Metabolic and Cognitive Diseases

(2014) Alexander J.S. Choi et al.   MOLECULES AND CELLS

Relaxin Protects Astrocytes from Hypoxia In Vitro

(2014) Jordan M. Willcox et al.   PLoS One

P2×7 Receptor in the Kidneys of Diabetic Rats Submitted to Aerobic Training or to N-Acetylcysteine Supplementation

(2014) Adelson M. Rodrigues et al.   PLoS One

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

(2014) Beibei Luo et al.   PLoS One

Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling

(2013) Shohei Kumagai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The plasma levels of relaxin-2 and relaxin-3 in patients with diabetes

(2013) Xiaohui Zhang et al.   CLINICAL BIOCHEMISTRY

The purinergic 2X7receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation

(2013) Anna Solini et al.   JOURNAL OF PATHOLOGY

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

H3 Relaxin Demonstrates Antifibrotic Properties via the RXFP1 Receptor

(2011) Mohammed Akhter Hossain et al.   BIOCHEMISTRY

Testing the Role of P2X 7 Receptors in the Development of Type 1 Diabetes in Nonobese Diabetic Mice

(2011) Yi-Guang Chen et al.   JOURNAL OF IMMUNOLOGY

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY