Bisphosphonate Induces Osteonecrosis of the Jaw in Diabetic Mice via NLRP3/Caspase-1-Dependent IL-1β Mechanism

OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice

(2015) Rafael Scaf de Molon et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-1 Blockade in Autoinflammatory Syndromes

(2014) Adriana A. Jesus et al.   Annual Review of Medicine

American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update

(2014) Salvatore L. Ruggiero et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Phenotypic Transitions of Macrophages Orchestrate Tissue Repair

(2013) Margaret L. Novak et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-17-Mediated M1/M2 Macrophage Alteration Contributes to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws

(2013) Q. Zhang et al.   CLINICAL CANCER RESEARCH

Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments

(2013) Moritz Haneklaus et al.   CURRENT OPINION IN IMMUNOLOGY

Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice

(2013) R. E. Mirza et al.   DIABETES

Blocking Interleukin-1  Induces a Healing-Associated Wound Macrophage Phenotype and Improves Healing in Type 2 Diabetes

(2013) R. E. Mirza et al.   DIABETES

Diabetes mellitus and corticotherapy as risk factors for alendronate-related osteonecrosis of the jaws: A study in Wistar rats

(2013) Soraya A. Berti-Couto et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Diabetes mellitus and inflammatory pulpal and periapical disease: a review

(2013) S. M. F. Lima et al.   INTERNATIONAL ENDODONTIC JOURNAL

Diabetes Microvascular Disease and the Risk for bisphosphonate-related Osteonecrosis of the Jaw: A Single Center Study

(2013) Shira Molcho et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glyburide Reduces Bacterial Dissemination in a Mouse Model of Melioidosis

(2013) Gavin C. K. W. Koh et al.   PLoS Neglected Tropical Diseases

Statins and Pulmonary Fibrosis

(2012) Jin-Fu Xu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Novel Aspects of Mevalonate Pathway Inhibitors as Antitumor Agents

(2012) M. Thurnher et al.   CLINICAL CANCER RESEARCH

Mevalonate kinase deficiency, a metabolic autoinflammatory disease

(2012) Robert van der Burgh et al.   CLINICAL IMMUNOLOGY

HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation

(2012) Y.-H. Liao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Oral Bisphosphonate Exposure: Clinical Course and Outcomes

(2012) Felice S. O'Ryan et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Inflammasomes in wound healing and fibrosis

(2012) Carol M Artlett   JOURNAL OF PATHOLOGY

Effects of insulin-like growth factor I on alveolar bone remodeling in diabetic rats

(2012) Y. Fang et al.   JOURNAL OF PERIODONTAL RESEARCH

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Statins accelerate the onset of collagen type II-induced arthritis in mice

(2012) Rob J Vandebriel et al.   ARTHRITIS RESEARCH & THERAPY

A Retrospective Study Evaluating Frequency and Risk Factors of Osteonecrosis of the Jaw in 576 Cancer Patients Receiving Intravenous Bisphosphonates

(2011) Vivek Thumbigere-Math et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

DC-like cell-dependent activation of human natural killer cells by the bisphosphonate zoledronic acid is regulated by    T lymphocytes

(2011) O. Nussbaumer et al.   BLOOD

Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice

(2011) Rita Mirza et al.   CYTOKINE

Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production

(2011) Erica L. Scheller et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Diabetes mellitus negatively affects peri-implant bone formation in the diabetic domestic pig

(2011) Cornelius von Wilmowsky et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Tumour macrophages as potential targets of bisphosphonates

(2011) Thea L Rogers et al.   Journal of Translational Medicine

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Type 2 diabetes mellitus impairs bone healing of dental implants in GK rats

(2010) Feng Wang et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency

(2010) Alessandra Pontillo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Cell-based immunotherapy with mesenchymal stem cells cures bisphosphonate-related osteonecrosis of the jaw-like disease in mice

(2010) Takashi Kikuiri et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Differential Roles of Macrophages in Diverse Phases of Skin Repair

(2010) T. Lucas et al.   JOURNAL OF IMMUNOLOGY

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

(2010) D. Gris et al.   JOURNAL OF IMMUNOLOGY

Osteonecrosis of the Jaw and the Role of Macrophages

(2010) M. Pazianas   JNCI-Journal of the National Cancer Institute

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates

(2009) Pablo Pelegrin et al.   EMBO JOURNAL

A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses

(2009) Guangxun Meng et al.   IMMUNITY

Osteonecrosis of the jaw in patients with multiple myeloma treated with zoledronic acid

(2009) Sedat Cetiner et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway

(2009) Marta Coscia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells

(2009) E. M. Bradshaw et al.   JOURNAL OF IMMUNOLOGY

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Statin synergizes with LPS to induce IL-1β release by THP-1 cells through activation of caspase-1

(2008) Loes M. Kuijk et al.   MOLECULAR IMMUNOLOGY

Alendronate augments interleukin-1β release from macrophages infected with periodontal pathogenic bacteria through activation of caspase-1

(2008) Xue Deng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY