Lipid droplet consumption is functionally coupled to vacuole homeostasis independent of lipophagy

Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress

(2018) Eigo Takeda et al.   MOLECULAR BIOLOGY OF THE CELL

Lipid sensing by mTOR complexes viade novosynthesis of phosphatidic acid

(2017) Deepak Menon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for ESCRT- and clathrin-dependent microautophagy

(2017) Masahide Oku et al.   JOURNAL OF CELL BIOLOGY

Lipid droplets and liver disease: from basic biology to clinical implications

(2017) Nina L. Gluchowski et al.   Nature Reviews Gastroenterology & Hepatology

Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex

(2017) Brian M. Castellano et al.   SCIENCE

Deleting the DAG kinase Dgk1 augments yeast vacuole fusion through increased Ypt7 activity and altered membrane fluidity

(2017) Gregory E. Miner et al.   TRAFFIC

Vacuole membrane contact sites and domains: emerging hubs to coordinate organelle function with cellular metabolism

(2016) Pedro Carpio Malia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphorylation of Dgk1 Diacylglycerol Kinase by Casein Kinase II Regulates Phosphatidic Acid Production inSaccharomyces cerevisiae

(2016) Yixuan Qiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAFLD and diabetes mellitus

(2016) Herbert Tilg et al.   Nature Reviews Gastroenterology & Hepatology

Phosphatidic Acid Sequesters Sec18p fromcis-SNARE Complexes to Inhibit Priming

(2016) Matthew L. Starr et al.   TRAFFIC

Mdm1/Snx13 is a novel ER–endolysosomal interorganelle tethering protein

(2015) W. Mike Henne et al.   JOURNAL OF CELL BIOLOGY

Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in Saccharomyces cerevisiae

(2015) Bobbiejane Stauffer et al.   MOLECULAR BIOLOGY OF THE CELL

Lipid partitioning at the nuclear envelope controls membrane biogenesis

(2015) Antonio Daniel Barbosa et al.   MOLECULAR BIOLOGY OF THE CELL

The vacuole/lysosome is required for cell-cycle progression

(2015) Yui Jin et al.   eLife

The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

(2015) Martin Müller et al.   eLife

Regulation of lipid droplet dynamics in Saccharomyces cerevisiae depends on the Rab7-like Ypt7p, HOPS complex and V1-ATPase

(2015) I. Bouchez et al.   Biology Open

Stationary phase lipophagy as a cellular mechanism to recycle sterols during quiescence

(2014) Chao-Wen Wang   Autophagy

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

Comprehensive Lipidome Analysis by Shotgun Lipidomics on a Hybrid Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer

(2014) Reinaldo Almeida et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

TORC1 Inhibition Induces Lipid Droplet Replenishment in Yeast

(2014) Juliana B. Madeira et al.   MOLECULAR AND CELLULAR BIOLOGY

TORC1 Regulates Pah1 Phosphatidate Phosphatase Activity via the Nem1/Spo7 Protein Phosphatase Complex

(2014) Emmanuelle Dubots et al.   PLoS One

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

(2014) Daniel F. Markgraf et al.   Cell Reports

Organization and function of membrane contact sites

(2013) Sebastian C.J. Helle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Central Role for mTOR in Lipid Homeostasis

(2013) Dudley W. Lamming et al.   Cell Metabolism

Phosphorylation of Lipin 1 and Charge on the Phosphatidic Acid Head Group Control Its Phosphatidic Acid Phosphatase Activity and Membrane Association

(2013) James M. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid droplet autophagy in the yeast Saccharomyces cerevisiae

(2013) Tim van Zutphen et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of Genes Affecting Vacuole Membrane Fragmentation in Saccharomyces cerevisiae

(2013) Lydie Michaillat et al.   PLoS One

Lipid Droplets and Cellular Lipid Metabolism

(2012) Tobias C. Walther et al.   Annual Review of Biochemistry

Phospholipids and lipid droplets

(2012) Anke Penno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat--Store 'em Up or Burn 'em Down

(2012) S. D. Kohlwein et al.   GENETICS

Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1

(2012) Lydie Michaillat et al.   MOLECULAR BIOLOGY OF THE CELL

Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

(2012) Tammy T. Nguyen et al.   TRAFFIC

Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pHc in Saccharomyces cerevisiae

(2012) Rick Orij et al.   GENOME BIOLOGY

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Phosphatidic Acid Activates Mammalian Target of Rapamycin Complex 1 (mTORC1) Kinase by Displacing FK506 Binding Protein 38 (FKBP38) and Exerting an Allosteric Effect

(2011) Mee-Sup Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast Lipin 1 Orthologue Pah1p Regulates Vacuole Homeostasis and Membrane Fusion

(2011) Terry Sasser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

(2011) Oludotun Adeyo et al.   JOURNAL OF CELL BIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Membrane Fusion: Five Lipids, Four SNAREs, Three Chaperones, Two Nucleotides, and a Rab, All Dancing in a Ring on Yeast Vacuoles

(2010) William Wickner   Annual Review of Cell and Developmental Biology

DGK1-encoded Diacylglycerol Kinase Activity Is Required for Phospholipid Synthesis during Growth Resumption from Stationary Phase inSaccharomyces cerevisiae

(2010) Stylianos Fakas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Yeast vps Class E Mutants: The Beginning of the Molecular Genetic Analysis of Multivesicular Body Biogenesis

(2010) Emily M. Coonrod et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

(2010) B. P. Young et al.   SCIENCE

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

(2008) Joji Mima et al.   EMBO JOURNAL

Vacuolar and Plasma Membrane Proton Pumps Collaborate to Achieve Cytosolic pH Homeostasis in Yeast

(2008) Gloria A. Martínez-Muñoz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the YeastDGK1-encoded CTP-dependent Diacylglycerol Kinase

(2008) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional genomic screen reveals genes involved in lipid-droplet formation and utilization

(2008) Yi Guo et al.   NATURE

Ist1 Regulates Vps4 Localization and Assembly

(2007) Christian Dimaano et al.   MOLECULAR BIOLOGY OF THE CELL