Loss ofFgfr1in chondrocytes inhibits osteoarthritis by promoting autophagic activity in temporomandibular joint

Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice

(2016) Siru Zhou et al.   Scientific Reports

Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice

(2016) Junzhou Tang et al.   Arthritis & Rheumatology

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

(2016) Wei Xu et al.   Scientific Reports

Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis

(2015) Thibault Bouderlique et al.   ANNALS OF THE RHEUMATIC DISEASES

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia

(2015) Xiaofeng Wang et al.   Autophagy

Current Understanding of Pathogenesis and Treatment of TMJ Osteoarthritis

(2015) X.D. Wang et al.   JOURNAL OF DENTAL RESEARCH

Wnt5a/Ror2 Mediates Temporomandibular Joint Subchondral Bone Remodeling

(2015) T. Yang et al.   JOURNAL OF DENTAL RESEARCH

FGF signalling regulates bone growth through autophagy

(2015) Laura Cinque et al.   NATURE

Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2

(2015) Shurei Sugita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Fibroblast Growth Factor signaling pathway

(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

The Relationship of Autophagy Defects to Cartilage Damage During Joint Aging in a Mouse Model

(2015) Beatriz Caramés et al.   Arthritis & Rheumatology

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

(2014) Yue Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Changes of Temporomandibular Joint and Semaphorin 4D/Plexin-B1 Expression in a Mouse Model of Incisor Malocclusion

(2014) Lei Lu et al.   Journal of Oral & Facial Pain and Headache

Enhancement of chondrocyte autophagy is an early response in the degenerative cartilage of the temporomandibular joint to biomechanical dental stimulation

(2013) Mian Zhang et al.   APOPTOSIS

Deletion of the Transforming Growth Factor β Receptor Type II Gene in Articular Chondrocytes Leads to a Progressive Osteoarthritis-like Phenotype in Mice

(2013) Jie Shen et al.   ARTHRITIS AND RHEUMATISM

A discoidin domain receptor 1 knock-out mouse as a novel model for osteoarthritis of the temporomandibular joint

(2013) Boris Schminke et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis

(2013) Y.-D. Liu et al.   OSTEOARTHRITIS AND CARTILAGE

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice

(2012) Tujun Weng et al.   ARTHRITIS AND RHEUMATISM

Fibroblast growth factor-2 promotes catabolism via FGFR1-Ras-Raf-MEK1/2-ERK1/2 axis that coordinates with the PKCδ pathway in human articular chondrocytes

(2012) Dongyao Yan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family

(2012) Xin Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

FRS2α-Mediated FGF Signals Suppress Premature Differentiation of Cardiac Stem Cells Through Regulating Autophagy Activity

(2011) Jue Zhang et al.   CIRCULATION RESEARCH

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

(2011) Martin K. Lotz et al.   Nature Reviews Rheumatology

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

(2011) Dongyao Yan et al.   ARTHRITIS RESEARCH & THERAPY

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Degenerative Disorders of the Temporomandibular Joint: Etiology, Diagnosis, and Treatment

(2009) E. Tanaka et al.   JOURNAL OF DENTAL RESEARCH

Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis

(2008) Michael B. Ellman et al.   GENE

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

(2008) C. Settembre et al.   GENES & DEVELOPMENT

Altered functional loading causes differential effects in the subchondral bone and condylar cartilage in the temporomandibular joint from young mice

(2008) J. Chen et al.   OSTEOARTHRITIS AND CARTILAGE