Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

(2011) Meina Wang et al.   Annals of the New York Academy of Sciences

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Osteoarthritis year 2010 in review: pathomechanisms

(2011) W.B. van den Berg   OSTEOARTHRITIS AND CARTILAGE

Fibroblast growth factor 2: good or bad guy in the joint?

(2011) Tonia L Vincent   ARTHRITIS RESEARCH & THERAPY

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

(2011) Dongyao Yan et al.   ARTHRITIS RESEARCH & THERAPY

Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice

(2010) Lin Xu et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

(2010) S. Miyaki et al.   GENES & DEVELOPMENT

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

The role of ADAMTSs in arthritis

(2010) Edward A. Lin et al.   Protein & Cell

Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis

(2009) Shi-Lu Chia et al.   ARTHRITIS AND RHEUMATISM

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Developments in the scientific understanding of osteoarthritis

(2009) Steven B Abramson et al.   ARTHRITIS RESEARCH & THERAPY

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage

(2008) Yasunobu Sawaji et al.   ARTHRITIS AND RHEUMATISM

Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis

(2008) Michael B. Ellman et al.   GENE

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Tamoxifen-inducible Cre-recombination in articular chondrocytes of adult Col2a1-CreERT2 transgenic mice

(2007) M. Zhu et al.   OSTEOARTHRITIS AND CARTILAGE