Balance between senescence and apoptosis is regulated by telomere damage–induced association between p16 and caspase-3
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Title
Balance between senescence and apoptosis is regulated by telomere damage–induced association between p16 and caspase-3
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 293, Issue 25, Pages 9784-9800
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2018-05-11
DOI
10.1074/jbc.ra118.003506
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Note: Only part of the references are listed.- The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction
- (2017) Leonid A. Timashev et al. GENES & DEVELOPMENT
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- (2017) Salih Gencer et al. Science Signaling
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- (2017) Cory Rice et al. Nature Communications
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- The structure, kinetics and interactions of the -carboxysomal -carbonic anhydrase, CcaA
- (2016) L. D. McGurn et al. BIOCHEMICAL JOURNAL
- Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML
- (2016) Mohammed Dany et al. BLOOD
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- A facile method to prepare large quantities of active caspase-3 overexpressed by auto-induction in the C41(DE3) strain
- (2016) Dohyeon Hwang et al. PROTEIN EXPRESSION AND PURIFICATION
- Telomeric RNAs are essential to maintain telomeres
- (2016) Juan José Montero et al. Nature Communications
- Role of Telomeres and Telomerase in Aging and Cancer
- (2016) J. W. Shay Cancer Discovery
- Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640
- (2016) Clayton S. Lewis et al. Oncotarget
- Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis
- (2015) Kate A. Parham et al. FASEB JOURNAL
- The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo
- (2015) H. Venant et al. MOLECULAR CANCER THERAPEUTICS
- Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation
- (2015) Yinghui Li et al. NATURE CELL BIOLOGY
- TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
- (2015) Linda J Valentijn et al. NATURE GENETICS
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions
- (2015) J. Jiang et al. SCIENCE
- Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation
- (2015) Shanmugam Panneer Selvam et al. Science Signaling
- Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation
- (2015) Shanmugam Panneer Selvam et al. Science Signaling
- Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma
- (2014) J. Kummetha Venkata et al. BLOOD
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- (2014) Khelifa Arab et al. MOLECULAR CELL
- Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk
- (2014) Kyle M Walsh et al. NATURE GENETICS
- Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation
- (2013) Ylli Doksani et al. CELL
- The Role of Telomeres in Stem Cells and Cancer
- (2013) Cagatay Günes et al. CELL
- p16INK4a protects against dysfunctional telomere–induced ATR-dependent DNA damage responses
- (2013) Yang Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
- (2013) Bettina Balk et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TERT Promoter Mutations in Familial and Sporadic Melanoma
- (2013) S. Horn et al. SCIENCE
- Highly Recurrent TERT Promoter Mutations in Human Melanoma
- (2013) F. W. Huang et al. SCIENCE
- Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis
- (2012) Suriyan Ponnusamy et al. EMBO Molecular Medicine
- mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription
- (2012) Adam R. Pont et al. MOLECULAR CELL
- Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
- (2012) R David Sentelle et al. Nature Chemical Biology
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers
- (2010) Kristy L. Richards et al. CANCER
- Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
- (2010) Graham M. Strub et al. FASEB JOURNAL
- Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2
- (2010) K. J. French et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
- (2010) Sergio E. Alvarez et al. NATURE
- Practical protocols for production of very high yields of recombinant proteins usingEscherichia coli
- (2009) Arun Sivashanmugam et al. PROTEIN SCIENCE
- Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
- (2009) N. C. Hait et al. SCIENCE
- Promoter Methylation of Genes in and around the Candidate Lung Cancer Susceptibility Locus 6q23-25
- (2008) M. Tessema et al. CANCER RESEARCH
- Structure of the Tribolium castaneum telomerase catalytic subunit TERT
- (2008) Andrew J. Gillis et al. NATURE
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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