Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

(2018) Chun-ling Dai et al.   Alzheimers Research & Therapy

Hyperphosphorylated Tau is a Cause of Neuronal Dysfunction in Tauopathy

(2017) Akihiko Takashima   JOURNAL OF ALZHEIMERS DISEASE

Hyperphosphorylation determines both the spread and the morphology of tau pathology

(2016) Wen Hu et al.   Alzheimers & Dementia

Structure and function of legumain in health and disease

(2016) Elfriede Dall et al.   BIOCHIMIE

Repetitive head trauma, chronic traumatic encephalopathy and tau: Challenges in translating from mice to men

(2016) Joseph O. Ojo et al.   EXPERIMENTAL NEUROLOGY

Blood–Brain Barrier Dysfunction as a Hallmark Pathology in Chronic Traumatic Encephalopathy

(2016) Colin P. Doherty et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

(2015) Sandy R. Shultz et al.   BRAIN

Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I

(2015) Nana Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

(2015) Shuko Takeda et al.   Nature Communications

Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease

(2015) Nana Jin et al.   Scientific Reports

Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation

(2015) Yifan Wang et al.   Scientific Reports

Tau Reduction Diminishes Spatial Learning and Memory Deficits after Mild Repetitive Traumatic Brain Injury in Mice

(2015) Jason S. Cheng et al.   PLoS One

Cytoplasmic Retention of Protein Phosphatase 2A Inhibitor 2 (I2PP2A) Induces Alzheimer-like Abnormal Hyperphosphorylation of Tau

(2014) Mohammad Arif et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury

(2014) Dhananjay R Namjoshi et al.   Molecular Neurodegeneration

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

(2014) Zhentao Zhang et al.   NATURE MEDICINE

Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome

(2014) Philip H Montenigro et al.   Alzheimers Research & Therapy

Incidence of sport-related traumatic brain injury and risk factors of severity: a population-based epidemiologic study

(2013) Anbesaw W. Selassie et al.   ANNALS OF EPIDEMIOLOGY

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model

(2013) Benoit C. Mouzon et al.   ANNALS OF NEUROLOGY

Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

(2013) Gustavo Basurto-Islas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repetitive Mild Traumatic Brain Injury Augments Tau Pathology and Glial Activation in Aged hTau Mice

(2013) Joseph-Olubunmi Ojo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

(2013) Douglas H. Smith et al.   Nature Reviews Neurology

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury

(2013) Terry Yin et al.   PLoS One

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

The spectrum of disease in chronic traumatic encephalopathy

(2012) Ann C. McKee et al.   BRAIN

Extracellular Brain Ph with or without Hypoxia is a Marker of Profound Metabolic Derangement and Increased Mortality after Traumatic Brain Injury

(2012) Ivan Timofeev et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Repetitive Mild Traumatic Brain Injury in a Mouse Model Produces Learning and Memory Deficits Accompanied by Histological Changes

(2012) Benoit Mouzon et al.   JOURNAL OF NEUROTRAUMA

Cognitive decline in older adults with a history of traumatic brain injury

(2012) Laura Moretti et al.   LANCET NEUROLOGY

Incidence of traumatic brain injury in New Zealand: a population-based study

(2012) Valery L Feigin et al.   LANCET NEUROLOGY

Widespread Tau and Amyloid-Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans

(2011) Victoria E. Johnson et al.   BRAIN PATHOLOGY

Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2PP2A/SET

(2011) Lisette Arnaud et al.   FEBS LETTERS

Controlled Cortical Impact Traumatic Brain Injury in 3xTg-AD Mice Causes Acute Intra-Axonal Amyloid-  Accumulation and Independently Accelerates the Development of Tau Abnormalities

(2011) H. T. Tran et al.   JOURNAL OF NEUROSCIENCE

A mouse model of human repetitive mild traumatic brain injury

(2011) Michael J. Kane et al.   JOURNAL OF NEUROSCIENCE METHODS

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment

(2010) Xiaochuan Wang et al.   FASEB JOURNAL

The Asparaginyl Endopeptidase Legumain after Experimental Stroke

(2010) Taku Ishizaki et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase

(2008) Zhixue Liu et al.   MOLECULAR CELL