Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

An experimental rat model of sporadic Alzheimer’s disease and rescue of cognitive impairment with a neurotrophic peptide

(2011) Silvia Bolognin et al.   ACTA NEUROPATHOLOGICA

Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2PP2A/SET

(2011) Lisette Arnaud et al.   FEBS LETTERS

Nucleoplasmic calcium regulates cell proliferation through legumain

(2011) Viviane Andrade et al.   JOURNAL OF HEPATOLOGY

Stat3 controls lysosomal-mediated cell death in vivo

(2011) Peter A. Kreuzaler et al.   NATURE CELL BIOLOGY

Translocation of Lysosomal Cathepsin D Caused by Oxidative Stress or Proteasome Inhibition in Primary Cultured Neurons and Astrocytes

(2010) Yuri Miura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment

(2010) Xiaochuan Wang et al.   FASEB JOURNAL

Hypothesis on the Relationship Between the Change in Intracellular pH and Incidence of Sporadic Alzheimer's Disease or Vascular Dementia

(2010) Boyan Fang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The Asparaginyl Endopeptidase Legumain after Experimental Stroke

(2010) Taku Ishizaki et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Direct Measurement of Cathepsin B Activity in the Cytosol of Apoptotic Cells by an Activity-Based Probe

(2009) Matthew R. Pratt et al.   CHEMISTRY & BIOLOGY

BlastocystisLegumain Is Localized on the Cell Surface, and Specific Inhibition of Its Activity Implicates a Pro-survival Role for the Enzyme

(2009) Binhui Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress and Autophagy in the Regulation of Lysosome-Dependent Neuron Death

(2008) Violetta N. Pivtoraiko et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

(2008) Valerie Clerin et al.   ATHEROSCLEROSIS

Neuroprotective Actions of PIKE-L by Inhibition of SET Proteolytic Degradation by Asparagine Endopeptidase

(2008) Zhixue Liu et al.   MOLECULAR CELL