Type 1 Diabetes and Its Multi-Factorial Pathogenesis: The Putative Role of NK Cells

NK cells in autoimmune diseases: Linking innate and adaptive immune responses

(2018) Elena Gianchecchi et al.   AUTOIMMUNITY REVIEWS

Identification of GAD65 AA 114-122 reactive 'memory-like' NK cells in newly diagnosed Type 1 diabetic patients by HLA-class I pentamers

(2017) Valentina Perri et al.   PLoS One

Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice

(2017) Javier A. Carrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural Killer Cells in the Orchestration of Chronic Inflammatory Diseases

(2017) Luca Parisi et al.   Journal of Immunology Research

The Role of Dendritic Cell Maturation in the Induction of Insulin-Dependent Diabetes Mellitus

(2017) Jacques C. Mbongue et al.   Frontiers in Immunology

Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response

(2017) Matthew Clark et al.   Frontiers in Immunology

The Expanding Role of Natural Killer Cells in Type 1 Diabetes and Immunotherapy

(2016) Chris Fraker et al.   Current Diabetes Reports

Innate lymphoid cells in normal and disease: An introductory overview

(2016) Lorenzo Moretta et al.   IMMUNOLOGY LETTERS

Insulitis in the pathogenesis of type 1 diabetes

(2016) Alberto Pugliese   PEDIATRIC DIABETES

Experimental Diabetes Mellitus in Different Animal Models

(2016) Amin Al-awar et al.   Journal of Diabetes Research

The role of natural killer cells in pathogenesis of autoimmune diseases

(2015) Katarzyna Popko et al.   Central European Journal of Immunology

Blood-based signatures in type 1 diabetes

(2015) Susanne M. Cabrera et al.   DIABETOLOGIA

Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus

(2015) Valentina Perri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent findings on the role of natural killer cells in the pathogenesis of systemic lupus erythematosus

(2015) R. Spada et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting Natural Killer Cell Reactivity by Employing Antibody to NKp46: Implications for Type 1 Diabetes

(2015) Rami Yossef et al.   PLoS One

High frequency of activated NKp46+natural killer cells in patients with new diagnosed of latent autoimmune diabetes in adults

(2014) Ye Wang et al.   AUTOIMMUNITY

Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

(2014) Sefina Arif et al.   DIABETES

Noncytotoxic Functions of NK Cells: Direct Pathogen Restriction and Assistance to Adaptive Immunity

(2014) T. Strowig et al.   JOURNAL OF IMMUNOLOGY

The Role of Natural Cytotoxicity Receptors in Various Pathologies: Emphasis on Type I Diabetes

(2014) Jonatan Enk et al.   Frontiers in Immunology

Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse

(2013) G. Kuriya et al.   DIABETOLOGIA

Low gene expression levels of activating receptors of natural killer cells (NKG2E and CD94) in patients with fulminant type 1 diabetes

(2013) Shinsuke Nakata et al.   IMMUNOLOGY LETTERS

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

(2013) Anette G. Ziegler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic and Environmental Determinants of Human NK Cell Diversity Revealed by Mass Cytometry

(2013) A. Horowitz et al.   Science Translational Medicine

The Pathogenesis and Natural History of Type 1 Diabetes

(2013) M. A. Atkinson   Cold Spring Harbor Perspectives in Medicine

Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?

(2012) Y. Simoni et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes

(2012) Tom L. Van Belle et al.   JOURNAL OF AUTOIMMUNITY

Molecular definition of the identity and activation of natural killer cells

(2012) Natalie A Bezman et al.   NATURE IMMUNOLOGY

Experimental Strategies in Autoimmunity: Antagonists of Cytokines and their Receptors, Nanocarriers, Inhibitors of Immunoproteasome, Leukocyte Migration and Protein Kinases

(2011) Alessandra Fierabracci et al.   CURRENT PHARMACEUTICAL DESIGN

Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling

(2011) Huilian Qin et al.   DIABETES

Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

(2011) Alessandra Ferraro et al.   DIABETES

Allergen-Specific Transforming Growth Factor-β-Producing CD19(+)CD5(+) Regulatory B-Cell (Br3) Responses in Human Late Eczematous Allergic Reactions to Cow's Milk

(2011) Jae Ho Lee et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Natural killer cell memory

(2011) Silke Paust et al.   NATURE IMMUNOLOGY

Natural killer cells are required for accelerated type 1 diabetes driven by interferon-β

(2010) A. Alba et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency

(2010) C. Åkesson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The dissociation activation model of B cell antigen receptor triggering

(2010) Jianying Yang et al.   FEBS LETTERS

Activating and inhibitory receptors of natural killer cells

(2010) Hollie J Pegram et al.   IMMUNOLOGY AND CELL BIOLOGY

Distinct Phenotype and Function of NK Cells in the Pancreas of Nonobese Diabetic Mice

(2010) Hanna Brauner et al.   JOURNAL OF IMMUNOLOGY

The role of B cells in regulating the magnitude of immune response

(2010) Seiho Nagafuchi   MICROBIOLOGY AND IMMUNOLOGY

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets

(2009) J. Yu et al.   BLOOD

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE

Detection of GAD65 Autoreactive T-Cells by HLA Class I Tetramers in Type 1 Diabetic Patients

(2009) Laura Giuliani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

(2009) N. Satoh-Takayama et al.   JOURNAL OF IMMUNOLOGY

The role of the activating receptor NKG2D in autoimmunity

(2009) Tom L. Van Belle et al.   MOLECULAR IMMUNOLOGY

The activating receptor NKp46 is essential for the development of type 1 diabetes

(2009) Chamutal Gur et al.   NATURE IMMUNOLOGY

Cytokine-induced memory-like natural killer cells

(2009) Megan A. Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NK cells in autoimmunity: A two-edg'd weapon of the immune system

(2008) Roberto Perricone et al.   AUTOIMMUNITY REVIEWS

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

(2008) J. S. Allen et al.   DIABETES

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

(2008) Nadia Guerra et al.   IMMUNITY

Mistaken notions about natural killer cells

(2008) Wayne M Yokoyama   NATURE IMMUNOLOGY

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY