- Home
- Publications
- Publication Search
- Publication Details
Title
Blood-based signatures in type 1 diabetes
Authors
Keywords
Biomarker, Gene expression profiling, Innate immunity, Microarray, Review, Type 1 diabetes
Journal
DIABETOLOGIA
Volume 59, Issue 3, Pages 414-425
Publisher
Springer Nature
Online
2015-12-23
DOI
10.1007/s00125-015-3843-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset
- (2016) Susanne M. Cabrera et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes
- (2015) Aleksandar D. Kostic et al. Cell Host & Microbe
- Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes
- (2015) Marisa M. Fisher et al. DIABETES
- Serum Proteomes Distinguish Children Developing Type 1 Diabetes in a Cohort With HLA-Conferred Susceptibility
- (2015) Robert Moulder et al. DIABETES
- β Cell death and dysfunction during type 1 diabetes development in at-risk individuals
- (2015) Kevan C. Herold et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNA regulation of lymphocyte tolerance and autoimmunity
- (2015) Laura J. Simpson et al. JOURNAL OF CLINICAL INVESTIGATION
- Immunogenetics of type 1 diabetes mellitus
- (2015) Michael P. Morran et al. MOLECULAR ASPECTS OF MEDICINE
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Genomics in acute lymphoblastic leukaemia: insights and treatment implications
- (2015) Kathryn G. Roberts et al. Nature Reviews Clinical Oncology
- The role for gut permeability in the pathogenesis of type 1 diabetes - a solid or leaky concept?
- (2015) Xia Li et al. PEDIATRIC DIABETES
- The Environment of Regulatory T Cell Biology: Cytokines, Metabolites, and the Microbiome
- (2015) Romy E. Hoeppli et al. Frontiers in Immunology
- Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation
- (2014) Adriane F Evangelista et al. BMC Medical Genomics
- Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients
- (2014) Jana Kayserova et al. CLINICAL IMMUNOLOGY
- Risk of Type 1 Diabetes Progression in Islet Autoantibody-Positive Children Can Be Further Stratified Using Expression Patterns of Multiple Genes Implicated in Peripheral Blood Lymphocyte Activation and Function
- (2014) Y. Jin et al. DIABETES
- The Type 1 Diabetes Signature: Hardwired to Trigger Inflammation?
- (2014) Ken T. Coppieters et al. DIABETES
- Compromised Gut Microbiota Networks in Children With Anti-Islet Cell Autoimmunity
- (2014) David Endesfelder et al. DIABETES
- Molecular Signatures Differentiate Immune States in Type 1 Diabetic Families
- (2014) Yi-Guang Chen et al. DIABETES
- A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes
- (2014) R. C. Ferreira et al. DIABETES
- Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility
- (2014) H. Kallionpaa et al. DIABETES
- Timing of Gluten Introduction and Islet Autoimmunity in Young Children: Updated Results From the BABYDIET Study: Table 1
- (2014) Andreas Beyerlein et al. DIABETES CARE
- MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus
- (2014) Paula Takahashi et al. GENE
- Hydrolyzed Infant Formula and Early β-Cell Autoimmunity
- (2014) Mikael Knip et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics
- (2014) X. Wang et al. JOURNAL OF IMMUNOLOGY
- Coxsackievirus can persist in murine pancreas by deletion of 5′ terminal genomic sequences
- (2014) Steven Tracy et al. JOURNAL OF MEDICAL VIROLOGY
- A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients’ plasma
- (2014) Prasong Khaenam et al. Journal of Translational Medicine
- Gut microbiota, probiotics and diabetes
- (2014) Aline Corado Gomes et al. Nutrition Journal
- The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis
- (2014) S. Blankley et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Fecal microbiota imbalance in Mexican children with type 1 diabetes
- (2014) María Esther Mejía-León et al. Scientific Reports
- Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study
- (2013) Mora Murri et al. BMC Medicine
- Anti-interferon alpha treatment in SLE
- (2013) Kyriakos A. Kirou et al. CLINICAL IMMUNOLOGY
- Immune Therapy and -Cell Death in Type 1 Diabetes
- (2013) J. Lebastchi et al. DIABETES
- Coxsackievirus B1 Is Associated With Induction of -Cell Autoimmunity That Portends Type 1 Diabetes
- (2013) O. H. Laitinen et al. DIABETES
- The Expression of Inflammatory Genes Is Upregulated in Peripheral Blood of Patients With Type 1 Diabetes
- (2013) Yulan Jin et al. DIABETES CARE
- Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes
- (2013) Y-G Chen et al. GENES AND IMMUNITY
- The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3
- (2013) Zuojia Chen et al. IMMUNITY
- Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity
- (2013) Jorg van Loosdregt et al. IMMUNITY
- Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children
- (2013) Anette G. Ziegler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes
- (2013) Qibin Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- HLA Class II Molecules Influence Susceptibility versus Protection in Inflammatory Diseases by Determining the Cytokine Profile
- (2013) A. K. Mangalam et al. JOURNAL OF IMMUNOLOGY
- Infection of human islets of langerhans with two strains of coxsackie B virus serotype 1: Assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway
- (2013) Mahesh Anagandula et al. JOURNAL OF MEDICAL VIROLOGY
- Peripheral Blood Monocyte Gene Expression Profile Clinically Stratifies Patients With Recent-Onset Type 1 Diabetes
- (2012) Katharine M. Irvine et al. DIABETES
- The multiple origins of Type 1 diabetes
- (2012) A. Pugliese DIABETIC MEDICINE
- Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease
- (2012) M. A. Atkinson et al. DIABETOLOGIA
- Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1
- (2012) S. J. Richardson et al. DIABETOLOGIA
- Trends in childhood type 1 diabetes incidence in Europe during 1989–2008: evidence of non-uniformity over time in rates of increase
- (2012) C. C. Patterson et al. DIABETOLOGIA
- Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes
- (2012) H Levy et al. GENES AND IMMUNITY
- Gene expression changes in human islets exposed to type 1 diabetic serum
- (2012) Andrew M. Jackson et al. Islets
- Genetics of Type 1 Diabetes
- (2011) A. K. Steck et al. CLINICAL CHEMISTRY
- Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis
- (2011) James C. Lee et al. JOURNAL OF CLINICAL INVESTIGATION
- Use of transcriptional signatures induced in lymphoid and myeloid cell lines as an inflammatory biomarker in Type 1 diabetes
- (2011) Shuang Jia et al. PHYSIOLOGICAL GENOMICS
- Detection of cell death in diabetes using differentially methylated circulating DNA
- (2011) E. M. Akirav et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Healthy First-Degree Relatives of Patients with Type 1 Diabetes Exhibit Significant Differences in Basal Gene Expression Pattern of Immunocompetent Cells Compared to Controls: Expression Pattern as Predeterminant of Autoimmune Diabetes
- (2011) K. Stechova et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- A Genomic Approach to Human Autoimmune Diseases
- (2010) Virginia Pascual et al. Annual Review of Immunology
- Autoimmune Markers in Diabetes
- (2010) W. E. Winter et al. CLINICAL CHEMISTRY
- Monocyte Gene-Expression Profiles Associated With Childhood-Onset Type 1 Diabetes and Disease Risk: A Study of Identical Twins
- (2010) H. Beyan et al. DIABETES
- Identification of a Serum-Induced Transcriptional Signature Associated With Type 1 Diabetes in the BioBreeding Rat
- (2010) M. Kaldunski et al. DIABETES
- IFN-γ and IL-10 islet-antigen-specific T cell responses in autoantibody-negative first-degree relatives of patients with type 1 diabetes
- (2010) L. G. Petrich de Marquesini et al. DIABETOLOGIA
- Epidemiology of Type 1 Diabetes
- (2010) David M. Maahs et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Specific gene expression signature associated with development of autoimmune type-I diabetes using whole-blood microarray analysis
- (2010) F Reynier et al. GENES AND IMMUNITY
- Etiology of Type 1 Diabetes
- (2010) John A. Todd IMMUNITY
- Toward defining the autoimmune microbiome for type 1 diabetes
- (2010) Adriana Giongo et al. ISME Journal
- Early suppression of immune response pathways characterizes children with prediabetes in genome-wide gene expression profiling
- (2010) Laura L. Elo et al. JOURNAL OF AUTOIMMUNITY
- Altered toll-like receptor signaling pathways in human type 1 diabetes
- (2010) Adam J. Meyers et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity
- (2010) Mikael Knip et al. NEW ENGLAND JOURNAL OF MEDICINE
- Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors
- (2010) A. K. Benson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enteroviruses and type 1 diabetes: towards a better understanding of the relationship
- (2010) Hela Jaïdane et al. REVIEWS IN MEDICAL VIROLOGY
- The geoepidemiology of type 1 diabetes
- (2009) Andrea T. Borchers et al. AUTOIMMUNITY REVIEWS
- Association of Type 1 Diabetes With Month of Birth Among U.S. Youth: The SEARCH for Diabetes in Youth Study
- (2009) H. S. Kahn et al. DIABETES CARE
- Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide
- (2009) E. V. Moltchanova et al. DIABETIC MEDICINE
- Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
- (2009) Makoto Miyara et al. IMMUNITY
- Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells
- (2009) E. M. Bradshaw et al. JOURNAL OF IMMUNOLOGY
- Distinct Monocyte Gene-Expression Profiles in Autoimmune Diabetes
- (2008) R. C. Padmos et al. DIABETES
- The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity
- (2008) O. Vaarala et al. DIABETES
- -Cell Mass and Type 1 Diabetes: Going, Going, Gone?
- (2008) E. Akirav et al. DIABETES
- The Rising Incidence of Type 1 Diabetes Is Accounted for by Cases With Lower-Risk Human Leukocyte Antigen Genotypes
- (2008) S. Fourlanos et al. DIABETES CARE
- Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden
- (2008) M. Thunander et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
- (2008) Matej Orešič et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A core gut microbiome in obese and lean twins
- (2008) Peter J. Turnbaugh et al. NATURE
- Predominant Role of Host Genetics in Controlling the Composition of Gut Microbiota
- (2008) Zaruhi A. Khachatryan et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation