Insulitis in the pathogenesis of type 1 diabetes

Lipids and immunoinflammatory pathways of beta cell destruction

(2016) Yumi Imai et al.   DIABETOLOGIA

β-cell Mass in Nondiabetic Autoantibody-Positive Subjects: An Analysis Based on the Network for Pancreatic Organ Donors Database

(2016) Marc Diedisheim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization

(2016) Hedwich F. Kuipers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

(2015) A. Wiberg et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro

(2015) Lars Krogvold et al.   DIABETES

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes

(2015) Martha Campbell-Thompson et al.   DIABETES

Prevention and Reversal of Type 1 Diabetes—Past Challenges and Future Opportunities

(2015) Jay S. Skyler   DIABETES CARE

Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients

(2015) Shiva Reddy et al.   DIABETOLOGIA

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

(2015) Lars Krogvold et al.   DIABETOLOGIA

Expression Pattern of 12-Lipoxygenase in Human Islets With Type 1 Diabetes and Type 2 Diabetes

(2015) Wojciech J. Grzesik et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

β Cell death and dysfunction during type 1 diabetes development in at-risk individuals

(2015) Kevan C. Herold et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis

(2015) Nadine Nagy et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes

(2015) Tanya C. Burch et al.   PLoS One

Extracellular Matrix Components in the Pathogenesis of Type 1 Diabetes

(2014) Marika Bogdani et al.   Current Diabetes Reports

Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis

(2014) M. Bogdani et al.   DIABETES

Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

(2014) Lars Krogvold et al.   DIABETES

Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

(2014) Sefina Arif et al.   DIABETES

Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors

(2014) Richard A. Oram et al.   DIABETES CARE

Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study

(2014) Lars Krogvold et al.   DIABETOLOGIA

Islet inflammation in human type 1 diabetes mellitus

(2014) Noel G. Morgan et al.   IUBMB LIFE

Characterization of residualβcell function in long-standing type 1 diabetes

(2013) Jennifer L. Sherr et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

(2013) Richard A. Oram et al.   DIABETOLOGIA

The diagnosis of insulitis in human type 1 diabetes

(2013) M. L. Campbell-Thompson et al.   DIABETOLOGIA

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

(2013) Anette G. Ziegler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings

(2013) Alberto Pugliese et al.   PEDIATRIC DIABETES

The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human

(2012) E. Korpos et al.   DIABETES

Fall in C-Peptide During First 2 Years From Diagnosis: Evidence of at Least Two Distinct Phases From Composite Type 1 Diabetes TrialNet Data

(2012) C. J. Greenbaum et al.   DIABETES

Persistence of Prolonged C-peptide Production in Type 1 Diabetes as Measured With an Ultrasensitive C-peptide Assay

(2012) L. Wang et al.   DIABETES CARE

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

(2012) I. Marhfour et al.   DIABETOLOGIA

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of Autoantibodies in the TrialNet Natural History Study

(2011) K. Vehik et al.   DIABETES CARE

Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals

(2011) Ken T. Coppieters et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty - TEENDIAB: study design

(2011) Anette-Gabriele Ziegler et al.   PEDIATRIC DIABETES

Age-Corrected Beta Cell Mass Following Onset of Type 1 Diabetes Mellitus Correlates with Plasma C-Peptide in Humans

(2011) David J. Klinke   PLoS One

Accurate measurement of pancreatic islet  -cell mass using a second-generation fluorescent exendin-4 analog

(2011) T. Reiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulitis in human type 1 diabetes

(2011) Peter In't Veld   Islets

Recurrence of Type 1 Diabetes After Simultaneous Pancreas-Kidney Transplantation, Despite Immunosuppression, Is Associated With Autoantibodies and Pathogenic Autoreactive CD4 T-Cells

(2010) F. Vendrame et al.   DIABETES

Glucose Excursions Between States of Glycemia With Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1)

(2010) J. M. Sosenko et al.   DIABETES

Residual Insulin Production and Pancreatic  -Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study

(2010) H. A. Keenan et al.   DIABETES

Collecting high-quality pancreatic tissue for experimental study from organ donors with signs of β-cell autoimmunity

(2010) Sisko Tauriainen et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Dimorphic histopathology of long-standing childhood-onset diabetes

(2010) R. Gianani et al.   DIABETOLOGIA

Epidemiology of Type 1 Diabetes

(2010) David M. Maahs et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

(2010) Jason L. Gaglia et al.   JOURNAL OF CLINICAL INVESTIGATION

Progression to Diabetes in Relatives of Type 1 Diabetic Patients: Mechanisms and Mode of Onset

(2009) E. Ferrannini et al.   DIABETES

Preservation of  -Cell Function in Autoantibody-Positive Youth With Diabetes

(2009) C. J. Greenbaum et al.   DIABETES CARE

Analysis of pancreas tissue in a child positive for islet cell antibodies

(2008) M. Oikarinen et al.   DIABETOLOGIA

Extent of Beta Cell Destruction Is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus

(2008) David J. Klinke   PLoS One