- Home
- Publications
- Publication Search
- Publication Details
Title
EP4 as a Therapeutic Target for Aggressive Human Breast Cancer
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 4, Pages 1019
Publisher
MDPI AG
Online
2018-03-30
DOI
10.3390/ijms19041019
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- COX-2 induces oncogenic micro RNA miR655 in human breast cancer
- (2018) Mousumi Majumder et al. Scientific Reports
- EP4 receptor promotes invadopodia and invasion in human breast cancer
- (2017) Felix Tönisen et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Immunotherapy in Breast Cancer: the Emerging Role of PD-1 and PD-L1
- (2017) François Bertucci et al. Current Oncology Reports
- Upregulation of the S1P 3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE 2 and EP 2 /EP 4 activation
- (2016) Iuliia Filipenko et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling
- (2016) Hiromichi Fujino BIOLOGICAL & PHARMACEUTICAL BULLETIN
- G protein-coupled receptors as promising cancer targets
- (2016) Ying Liu et al. CANCER LETTERS
- Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer
- (2016) J F Hiken et al. ONCOGENE
- PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations
- (2016) Weiping Zou et al. Science Translational Medicine
- COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis
- (2016) Mousumi Majumder et al. STEM CELLS
- Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?
- (2015) G O'Callaghan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Abstract 275: ER-886046, an antagonist of PGE2 receptor type-4, induces an effective antitumor immune response in mice by attenuating intratumoral MDSCs and TAMs
- (2015) Diana I. Albu et al. CANCER RESEARCH
- COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation
- (2015) M. Majumder et al. MOLECULAR CANCER RESEARCH
- Antagonists of PD-1 and PD-L1 in Cancer Treatment
- (2015) Evan J. Lipson et al. SEMINARS IN ONCOLOGY
- Combination of EP4 antagonist and checkpoint inhibitors promotes anti-tumor effector T cells in preclinical tumor models
- (2015) Xingfeng Bao et al. Journal for ImmunoTherapy of Cancer
- Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer
- (2015) Jiabei He et al. Scientific Reports
- Tumor-Initiating and -Propagating Cells: Cells That We Would to Identify and Control
- (2015) Berit Bølge Tysnes NEOPLASIA
- Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions
- (2014) Mousumi Majumder et al. CANCER SCIENCE
- An EP4 Antagonist ONO-AE3-208 Suppresses Cell Invasion, Migration, and Metastasis of Prostate Cancer
- (2014) Song Xu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties
- (2013) Namita Kundu et al. BREAST CANCER RESEARCH AND TREATMENT
- E-type prostanoid receptor 4 (EP4) in disease and therapy
- (2013) Viktoria Konya et al. PHARMACOLOGY & THERAPEUTICS
- A prostaglandin E (PGE) receptor EP4 antagonist protects natural killer cells from PGE2-mediated immunosuppression and inhibits breast cancer metastasis
- (2013) Xinrong Ma et al. OncoImmunology
- Cancer Stem Cells: Current Status and Evolving Complexities
- (2012) Jane E. Visvader et al. Cell Stem Cell
- Personalized Medicine in Breast Cancer: A Systematic Review
- (2012) Sang-Hoon Cho et al. Journal of Breast Cancer
- Cyclooxygenase-2 up-regulates CCR7 expression via AKT-mediated phosphorylation and activation of Sp1 in breast cancer cells
- (2012) Chun-Wei Chuang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model
- (2012) Xiping Xin et al. LABORATORY INVESTIGATION
- Prostaglandin E2 EP receptors as therapeutic targets in breast cancer
- (2011) Jocelyn Reader et al. CANCER AND METASTASIS REVIEWS
- The role of the EP receptors for prostaglandin E2 in skin and skin cancer
- (2011) J. E. Rundhaug et al. CANCER AND METASTASIS REVIEWS
- Prostaglandin E2 (PGE2) suppresses natural killer cell function primarily through the PGE2 receptor EP4
- (2011) Dawn Holt et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Circulating microRNAs as Novel Minimally Invasive Biomarkers for Breast Cancer
- (2010) Helen M. Heneghan et al. ANNALS OF SURGERY
- Selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer risk
- (2010) Varun Ashok et al. BREAST
- Differential regulation of the aggressive phenotype of inflammatory breast cancer cells by prostanoid receptors EP3 and EP4
- (2010) Fredika M. Robertson et al. CANCER
- Relationship between cyclooxygenase-2 and human epidermal growth factor receptor 2 in vascular endothelial growth factor C up-regulation and lymphangiogenesis in human breast cancer
- (2010) Rabindra N. Bhattacharjee et al. CANCER SCIENCE
- Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis
- (2010) Nobuyoshi Kosaka et al. CANCER SCIENCE
- G protein-coupled receptors: novel targets for drug discovery in cancer
- (2010) Rosamaria Lappano et al. NATURE REVIEWS DRUG DISCOVERY
- A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation
- (2010) Aline Correa Abrahao et al. ORAL ONCOLOGY
- The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
- (2009) A. Greenhough et al. CARCINOGENESIS
- Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications
- (2009) Steven G. Gray et al. EUROPEAN JOURNAL OF CANCER
- Pharmacological activation of the prostaglandin E2 receptor EP4 improves cardiac function after myocardial ischaemia/reperfusion injury
- (2008) Keiichi Hishikari et al. CARDIOVASCULAR RESEARCH
- Aberrant crypt foci: are they intermediate endpoints of colon carcinogenesis in humans?
- (2008) Akshay K Gupta et al. CURRENT OPINION IN GASTROENTEROLOGY
- Cyclooxygenase-2 Up-regulates CCR7 via EP2/EP4 Receptor Signaling Pathways to Enhance Lymphatic Invasion of Breast Cancer Cells
- (2008) Mei-Ren Pan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
- (2008) Alysha K. Croker et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Cyclooxygenase-2-Linked Attenuation of Hypoxia-Induced Pulmonary Hypertension and Intravascular Thrombosis
- (2008) M.-C. Cathcart et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
- (2008) X. Li et al. JNCI-Journal of the National Cancer Institute
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now