Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 6, Pages 1668
Publisher
MDPI AG
Online
2018-06-05
DOI
10.3390/ijms19061668
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects
- (2018) Haroon Khan et al. BIOMEDICINE & PHARMACOTHERAPY
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Contamination of hepatotoxic pyrrolizidine alkaloids in retail honey in China
- (2018) Lin Zhu et al. FOOD CONTROL
- Toxic pyrrolizidine alkaloids provide a warning sign to overuse of the ethnomedicine Arnebia benthamii
- (2018) Latif Ahmad et al. JOURNAL OF ETHNOPHARMACOLOGY
- Anti-inflammatory of pyrrolizidine alkaloids from Heliotropium digynum
- (2018) Mohamed Aboelmagd et al. MEDICINAL CHEMISTRY RESEARCH
- Pyrrolizidine alkaloids in floral honeys of tropical Ghana and health risk assessment
- (2017) Emmanuel Letsyo et al. Food Additives & Contaminants Part B-Surveillance
- Development and validation of a QuEChERS method coupled to liquid chromatography and high resolution mass spectrometry to determine pyrrolizidine and tropane alkaloids in honey
- (2017) Marianna Martinello et al. FOOD CHEMISTRY
- Toxic pyrrolizidine alkaloids in herbal medicines commonly used in Ghana
- (2017) Emmanuel Letsyo et al. JOURNAL OF ETHNOPHARMACOLOGY
- Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N -oxides
- (2017) Xiaobo He et al. JOURNAL OF FOOD AND DRUG ANALYSIS
- Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
- (2017) Jeremy Robertson et al. NATURAL PRODUCT REPORTS
- A Balanced Risk–Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Tea and Herbal Infusions
- (2017) Michael Habs et al. Nutrients
- The long persistence of pyrrolizidine alkaloid-derived DNA adducts in vivo: kinetic study following single and multiple exposures in male ICR mice
- (2016) Lin Zhu et al. ARCHIVES OF TOXICOLOGY
- Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalis
- (2016) Themístocles da Silva Negreiros Neto et al. BIOMEDICINE & PHARMACOTHERAPY
- Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
- (2016) Mengbi Yang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- A fast and simple LC-ESI-MS/MS method for detecting pyrrolizidine alkaloids in honey with full validation and measurement uncertainty
- (2016) Andressa Camargo Valese et al. FOOD CONTROL
- Pyrrolizidine Alkaloids from Echium vulgare in Honey Originate Primarily from Floral Nectar
- (2016) Matteo A. Lucchetti et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Acetylcholinesterase inhibitory activity of pyrrolizidine alkaloids from Echium confusum Coincy
- (2016) Houari Benamar et al. NATURAL PRODUCT RESEARCH
- Pyrrolizidine alkaloids from Solenanthus lanatus DC. with acetylcholinesterase inhibitory activity
- (2016) Houari Benamar et al. NATURAL PRODUCT RESEARCH
- Pro-toxic 1,2-Dehydropyrrolizidine Alkaloid Esters, Including Unprecedented 10-Membered Macrocyclic Diesters, in the Medicinally-usedAlafiacf.caudataandAmphineurion marginatum(Apocynaceae: Apocynoideae: Nerieae and Apocyneae)
- (2016) Steven M. Colegate et al. PHYTOCHEMICAL ANALYSIS
- A 28-day oral toxicity study of echimidine and lasiocarpine in Wistar rats
- (2016) Rosalind R. Dalefield et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Interim relative potency factors for the toxicological risk assessment of pyrrolizidine alkaloids in food and herbal medicines
- (2016) Karl-Heinz Merz et al. TOXICOLOGY LETTERS
- Pyrrolizidine alkaloids in natural and experimental grass silages and implications for feed safety
- (2015) Christoph Gottschalk et al. ANIMAL FEED SCIENCE AND TECHNOLOGY
- Pyrrolizidine alkaloids inTussilago farfarafrom Bulgaria
- (2015) Anely Nedelcheva et al. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
- Sulfated glycans in inflammation
- (2015) Vitor H. Pomin EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Quantification of pyrrolizidine alkaloids in North American plants and honey by LC-MS: single laboratory validation
- (2015) Elizabeth M. Mudge et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Evaluation of Some Pyrrolizidine Alkaloids in Honey Samples from the Veneto Region (Italy) by LC-MS/MS
- (2015) Lucatello Lorena et al. Food Analytical Methods
- Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry
- (2015) Bharathi Avula et al. FOOD CHEMISTRY
- Safety concerns of herbal products and traditional Chinese herbal medicines: dehydropyrrolizidine alkaloids and aristolochic acid
- (2015) Bryan L. Stegelmeier et al. JOURNAL OF APPLIED TOXICOLOGY
- Blood Pyrrole-Protein Adducts—A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans
- (2015) Jianqing Ruan et al. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
- Hepatotoxic pyrrolizidine alkaloids in Emilia sonchifolia from Taiwan
- (2015) Cheng-Hong Hsieh et al. JOURNAL OF FOOD COMPOSITION AND ANALYSIS
- Detection of pyrrolizidine alkaloids in German licensed herbal medicinal teas
- (2015) M. Schulz et al. PHYTOMEDICINE
- Seasonal variability in pyrrolizidine alkaloids inSenecio inaequidensfrom the Val Venosta (Northern Italy)
- (2015) A. Eller et al. PLANT BIOSYSTEMS
- Disturbance of gene expression in primary human hepatocytes by hepatotoxic pyrrolizidine alkaloids: A whole genome transcriptome analysis
- (2015) Claudia Luckert et al. TOXICOLOGY IN VITRO
- An in vitro comparison of the cytotoxic potential of selected dehydropyrrolizidine alkaloids and some N-oxides
- (2015) Reuel A. Field et al. TOXICON
- Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease
- (2014) John A. Edgar et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Determination of pyrrolizidine alkaloids in tea, herbal drugs and honey
- (2014) Dorina Bodi et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Investigation of targeted pyrrolizidine alkaloids in traditional Chinese medicines and selected herbal teas sourced in Ireland using LC-ESI-MS/MS
- (2014) Caroline T. Griffin et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Analysis of Swiss honeys for pyrrolizidine alkaloids
- (2014) Christina Kast et al. JOURNAL OF APICULTURAL RESEARCH
- Pyrrolizidine alkaloids
- (2014) Jeremy Robertson et al. NATURAL PRODUCT REPORTS
- Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants
- (2013) Anja These et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Pyrrolizidine alkaloids: their occurrence in Spanish honey collected from purple viper’s bugloss (Echiumspp.)
- (2013) F.J. Orantes-Bermejo et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids and N-oxides in Butterbur (Petasites hybridus) with an offline 2D-combination of HPLC-UV and LC-MMI-ToF-MS
- (2013) Ahmet Alper Aydın et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Pyrrolizidine alkaloids from Liparis nervosa with inhibitory activities against LPS-induced NO production in RAW264.7 macrophages
- (2013) Shuai Huang et al. PHYTOCHEMISTRY
- Pyrrolizidine alkaloids in medicinal tea of Ageratum conyzoides
- (2013) Cristiane F. Bosi et al. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
- Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: A mechanism for its cytotoxic activity
- (2013) Prakash Appadurai et al. TOXICOLOGY LETTERS
- The medical plant butterbur (Petasites): Analytical and physiological (re)view
- (2012) Ahmet Alper Aydın et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Photoirradiation of dehydropyrrolizidine alkaloids—Formation of reactive oxygen species and induction of lipid peroxidation
- (2011) Yuewei Zhao et al. TOXICOLOGY LETTERS
- Changes inSenecio grisebachiipyrrolizidine alkaloids abundances and profiles as response to soil quality
- (2011) Margarita A. Yaber Grass et al. Journal of Plant Interactions
- A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-containing plants by using ultra performance liquid chromatography–tandem quadrupole mass spectrometry
- (2010) Yan Zhou et al. ANALYTICA CHIMICA ACTA
- Pyrrolizidine alkaloids in honey: comparison of analytical methods
- (2010) M. Kempf et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Pyrrolizidine alkaloids in food: downstream contamination in the food chain caused by honey and pollen
- (2010) M. Kempf et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Genotoxicity of pyrrolizidine alkaloids
- (2010) Tao Chen et al. JOURNAL OF APPLIED TOXICOLOGY
- Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum
- (2010) Ge Lin et al. JOURNAL OF HEPATOLOGY
- Toxicity of pyrrolizidine alkaloids to humans and ruminants
- (2010) Helmut Wiedenfeld et al. PHYTOCHEMISTRY REVIEWS
- Attract and deter: a dual role for pyrrolizidine alkaloids in plant–insect interactions
- (2010) Mirka Macel PHYTOCHEMISTRY REVIEWS
- Pyrrolizidine alkaloids in pollen and pollen products
- (2009) Michael Kempf et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Pyrrolizidine alkaloid biosynthesis, evolution of a pathway in plant secondary metabolism
- (2009) Dietrich Ober et al. PHYTOCHEMISTRY
- Pyrrolizidine alkaloids in honey: Risk analysis by gas chromatography-mass spectrometry
- (2008) Michael Kempf et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine
- (2008) Qingsu Xia et al. TOXICOLOGY LETTERS
- Occurrence of pyrrolizidine alkaloids in three Ethiopian Solanecio species
- (2007) Kaleab Asres et al. BIOCHEMICAL SYSTEMATICS AND ECOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started