Human 3D Cultures as Models for Evaluating Magnetic Nanoparticle CNS Cytotoxicity after Short- and Repeated Long-Term Exposure

3D cellular spheroids as tools for understanding carboxylated quantum dot behavior in tumors

(2018) Greta Jarockyte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Intranasal instillation of iron oxide nanoparticles induces inflammation and perturbation of trace elements and neurotransmitters, but not behavioral impairment in rats

(2018) Dalel Askri et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Nano- and neurotoxicology: An emerging discipline

(2018) Anna Bencsik et al.   PROGRESS IN NEUROBIOLOGY

Iron oxide nanoparticles with different polymer coatings for photothermal therapy

(2017) Jia Yang et al.   JOURNAL OF NANOPARTICLE RESEARCH

Neurodegeneration with Brain Iron Accumulation

(2016) Susanne A. Schneider   Current Neurology and Neuroscience Reports

Cytotoxicity and proliferative capacity impairment induced on human brain cell cultures after short- and long-term exposure to magnetite nanoparticles

(2016) Teresa Coccini et al.   JOURNAL OF APPLIED TOXICOLOGY

Transitioning from multi-phase to single-phase microfluidics for long-term culture and treatment of multicellular spheroids

(2016) Kay S. McMillan et al.   LAB ON A CHIP

Folate attached, curcumin loaded Fe3O4 nanoparticles: A novel multifunctional drug delivery system for cancer treatment

(2016) Le Thi Thu Huong et al.   MATERIALS CHEMISTRY AND PHYSICS

Casp3/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis

(2016) Yue Yuan et al.   NANO LETTERS

Physicochemical properties of engineered nanomaterials that influence their nervous system distribution and effects

(2016) Robert A. Yokel   Nanomedicine-Nanotechnology Biology and Medicine

Magnetite pollution nanoparticles in the human brain

(2016) Barbara A. Maher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Approaches to Develop Alternative Testing Strategies to Inform Human Health Risk Assessment of Nanomaterials

(2016) Vicki Stone et al.   RISK ANALYSIS

In vitrocytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests

(2015) Carla Costa et al.   JOURNAL OF APPLIED TOXICOLOGY

Superparamagnetic iron oxide nanoparticles exert different cytotoxic effects on cells grown in monolayer cell culture versus as multicellular spheroids

(2015) Anja Theumer et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids

(2015) Annkathrin Hornung et al.   MOLECULES

A 3D human neural cell culture system for modeling Alzheimer's disease

(2015) Young Hye Kim et al.   Nature Protocols

Recent progress on magnetic iron oxide nanoparticles: synthesis, surface functional strategies and biomedical applications

(2015) Wei Wu et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Polyethyleneimine-Coated Fe3O4 Nanoparticles for Efficient siRNA Delivery to Human Mesenchymal Stem Cells Derived from Different Tissues

(2015) Dianbao Zhang et al.   Science of Advanced Materials

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Physical Stimuli-Induced Chondrogenic Differentiation of Mesenchymal Stem Cells Using Magnetic Nanoparticles

(2015) Boram Son et al.   Advanced Healthcare Materials

Iron entry in neurons and astrocytes: a link with synaptic activity

(2015) Franca Codazzi et al.   Frontiers in Molecular Neuroscience

Uptake and metabolism of iron and iron oxide nanoparticles in brain astrocytes: Figure 1

(2015) Michaela C. Hohnholt et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Fe3O4/PVIM-Ni2+ Magnetic Composite Microspheres for Highly Specific Separation of Histidine-Rich Proteins

(2014) Yuting Zhang et al.   ACS Applied Materials & Interfaces

A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies

(2014) Sreenivasa C. Ramaiahgari et al.   ARCHIVES OF TOXICOLOGY

Large-Scale Synthesis of Colloidal Fe3O4 Nanoparticles Exhibiting High Heating Efficiency in Magnetic Hyperthermia

(2014) Yury V. Kolen’ko et al.   Journal of Physical Chemistry C

Uptake and Metabolism of Iron Oxide Nanoparticles in Brain Cells

(2014) Charlotte Petters et al.   NEUROCHEMICAL RESEARCH

Engineered nanoparticles. How brain friendly is this new guest?

(2014) Francesca A. Cupaioli et al.   PROGRESS IN NEUROBIOLOGY

Effect of Micro- and Nanomagnetite on Printing Toner Properties

(2014) Maryam Ataeefard et al.   TheScientificWorldJOURNAL

Validation of in vitro assays to measure cytotoxicity in 3D cell cultures

(2014) Terry Riss et al.   TOXICOLOGY LETTERS

Endocytotic uptake of iron oxide nanoparticles by cultured brain microglial cells

(2013) Eva M. Luther et al.   Acta Biomaterialia

Nano-enabled delivery systems across the blood–brain barrier

(2013) Seung Rim Hwang et al.   ARCHIVES OF PHARMACAL RESEARCH

Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model

(2013) Fahima Dilnawaz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In vivo nanoneurotoxicity screening using oxidative stress and neuroinflammation paradigms

(2013) Youngsoon Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Iron metabolism in the CNS: implications for neurodegenerative diseases

(2013) Tracey A. Rouault   NATURE REVIEWS NEUROSCIENCE

Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study

(2013) Yiyi Xu et al.   Particle and Fibre Toxicology

3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies

(2013) Daniel Mueller et al.   TOXICOLOGY IN VITRO

Superparamagnetic Iron Oxide Nanoparticles as MRI contrast agents for Non-invasive Stem Cell Labeling and Tracking

(2013) Li Li et al.   Theranostics

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Magnetic nanoparticles in primary neural cell cultures are mainly taken up by microglia

(2012) Josephine Pinkernelle et al.   BMC NEUROSCIENCE

Water-soluble Fe3O4 nanoparticles with high solubility for removal of heavy-metal ions from waste water

(2012) Lixia Wang et al.   DALTON TRANSACTIONS

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

Investigation on Mechanism of Growth Arrest Induced by Iron Oxide Nanoparticles in PC12 Cells

(2012) Jie Wu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus

(2012) Jie Wu et al.   NEUROTOXICOLOGY

Internal benchmarking of a human blood–brain barrier cell model for screening of nanoparticle uptake and transcytosis

(2011) Michelle Nic Ragnaill et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Anatomical site influences the differentiation of adipose-derived stem cells for Schwann-cell phenotype and function

(2011) Rossukon Kaewkhaw et al.   GLIA

Pharmacokinetic parameters and tissue distribution of magnetic Fe3O4 nanoparticles in mice

(2010) Baoan Chen   International Journal of Nanomedicine

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones

(2009) Anja Zensi et al.   JOURNAL OF CONTROLLED RELEASE

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

In vitro Toxicity Testing of Nanoparticles in 3D Cell Culture

(2009) Jungwoo Lee et al.   Small

3-D Tissue Culture Systems for the Evaluation and Optimization of Nanoparticle-Based Drug Carriers

(2008) Thomas Tyrel Goodman et al.   BIOCONJUGATE CHEMISTRY