Prostaglandin E2 and IL-23 interconnects STAT3 and RoRγ pathways to initiate Th17 CD4+ T-cell development during rheumatoid arthritis
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Prostaglandin E2 and IL-23 interconnects STAT3 and RoRγ pathways to initiate Th17 CD4+ T-cell development during rheumatoid arthritis
Authors
Keywords
Rheumatoid arthritis, Autoinflammation, Bone erosion, Prostaglandin E2, IL-17, IL-23, Th17, RANKL, STAT3 and RoRγ
Journal
INFLAMMATION RESEARCH
Volume 67, Issue 7, Pages 589-596
Publisher
Springer Nature
Online
2018-04-30
DOI
10.1007/s00011-018-1153-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Rheumatoid arthritis
- (2018) Josef S. Smolen et al. Nature Reviews Disease Primers
- G protein coupled receptors signaling pathways implicate in inflammatory and immune response of rheumatoid arthritis
- (2016) Jinling Shu et al. INFLAMMATION RESEARCH
- Citrullination and Carbamylation in the Pathophysiology of Rheumatoid Arthritis
- (2015) Ger J. M. Pruijn Frontiers in Immunology
- IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage
- (2014) G. L. Stritesky et al. JOURNAL OF IMMUNOLOGY
- Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937
- (2014) Nancy J Olsen et al. ARTHRITIS RESEARCH & THERAPY
- Emerging cell and cytokine targets in rheumatoid arthritis
- (2013) Gerd R. Burmester et al. Nature Reviews Rheumatology
- Review: The Interleukin-23/Interleukin-17 Axis in Spondyloarthritis Pathogenesis: Th17 and Beyond
- (2013) Judith A. Smith et al. Arthritis & Rheumatology
- Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: Implications for insufficiency fracture risk
- (2012) Masahiko Takahata et al. ARTHRITIS AND RHEUMATISM
- Progressive multifocal leukoencephalopathy associated with immunosuppressive therapy in rheumatic diseases: Evolving role of biologic therapies
- (2012) Eamonn S. Molloy et al. ARTHRITIS AND RHEUMATISM
- Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
- (2012) Iannis E Adamopoulos et al. ARTHRITIS RESEARCH & THERAPY
- Signaling in Innate Immunity and Inflammation
- (2012) K. Newton et al. Cold Spring Harbor Perspectives in Biology
- Interleukin-23: as a drug target for autoimmune inflammatory diseases
- (2011) Chunlei Tang et al. IMMUNOLOGY
- Anti-CCP antibodies: the past, the present and the future
- (2011) Walther J. van Venrooij et al. Nature Reviews Rheumatology
- The Pathogenesis of Rheumatoid Arthritis
- (2011) Iain B. McInnes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis
- (2010) Adriana M. C. Mus et al. ARTHRITIS AND RHEUMATISM
- Role of Th17 cells in human autoimmune arthritis
- (2010) Jan Leipe et al. ARTHRITIS AND RHEUMATISM
- Anti-inflammatory Agents: Present and Future
- (2010) Charles A. Dinarello CELL
- Prostaglandin E2-dependent IL-23 production in aged murine dendritic cells
- (2010) Rebecca G. Myer et al. EXPERIMENTAL GERONTOLOGY
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
- (2009) Katia Boniface et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The role of interleukin-17 in the pathogenesis of rheumatoid arthritis
- (2009) Sarah L. Gaffen Current Rheumatology Reports
- Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
- (2008) Dror Luger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
- (2008) Liang Zhou et al. NATURE
- Immunological decision-making: how does the immune system decide to mount a helper T-cell response?
- (2007) Gerard E. Kaiko et al. IMMUNOLOGY
- Crucial Involvement of the EP4 Subtype of Prostaglandin E Receptor in Osteoclast Formation by Proinflammatory Cytokines and Lipopolysaccharide
- (2006) Yoko Sakuma et al. JOURNAL OF BONE AND MINERAL RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now