Review: The Interleukin-23/Interleukin-17 Axis in Spondyloarthritis Pathogenesis: Th17 and Beyond
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Title
Review: The Interleukin-23/Interleukin-17 Axis in Spondyloarthritis Pathogenesis: Th17 and Beyond
Authors
Keywords
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Journal
Arthritis & Rheumatology
Volume 66, Issue 2, Pages 231-241
Publisher
Wiley
Online
2013-11-27
DOI
10.1002/art.38291
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Note: Only part of the references are listed.- Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells
- (2014) H. S. Goodridge et al. JOURNAL OF IMMUNOLOGY
- Peripheral joint inflammation in early onset spondyloarthritis is not specifically related to enthesitis
- (2013) Jacqueline E Paramarta et al. ANNALS OF THE RHEUMATIC DISEASES
- Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
- (2013) Francesco Ciccia et al. ANNALS OF THE RHEUMATIC DISEASES
- In Situ Analysis of Interleukin-23- and Interleukin-12-Positive Cells in the Spine of Patients With Ankylosing Spondylitis
- (2013) Heiner Appel et al. ARTHRITIS AND RHEUMATISM
- Combinatorial Control of Th17 and Th1 Cell Functions by Genetic Variations in Genes Associated With the Interleukin-23 Signaling Pathway in Spondyloarthritis
- (2013) Maryaline Coffre et al. ARTHRITIS AND RHEUMATISM
- HLA-B27 Alters the Response to Tumor Necrosis Factor α and Promotes Osteoclastogenesis in Bone Marrow Monocytes From HLA-B27-Transgenic Rats
- (2013) Gerlinde Layh-Schmitt et al. ARTHRITIS AND RHEUMATISM
- Brief Report: High-Throughput Sequencing ofIL23RReveals a Low-Frequency, Nonsynonymous Single-Nucleotide Polymorphism That Is Associated With Ankylosing Spondylitis in a Han Chinese Population
- (2013) Stuart I. Davidson et al. ARTHRITIS AND RHEUMATISM
- Interleukin-23: a promising therapeutic target in seronegative spondyloarthropathy
- (2013) Jonathan P Sherlock et al. CURRENT OPINION IN PHARMACOLOGY
- Th17 cell development: from the cradle to the grave
- (2013) Luis A. Zúñiga et al. IMMUNOLOGICAL REVIEWS
- Mechanisms underlying helper T-cell plasticity: Implications for immune-mediated disease
- (2013) Kiyoshi Hirahara et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
- (2013) Iain B McInnes et al. LANCET
- 17 and 23: prime numbers for ankylosing spondylitis?
- (2013) Robert A Colbert et al. LANCET
- Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial
- (2013) Dominique Baeten et al. LANCET
- The biochemistry and immunology of non-canonical forms of HLA-B27
- (2013) Jacqueline Shaw et al. MOLECULAR IMMUNOLOGY
- HLA-B27 misfolding and ankylosing spondylitis
- (2013) Robert A. Colbert et al. MOLECULAR IMMUNOLOGY
- Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
- (2013) Adrian Cortes et al. NATURE GENETICS
- Genetic insights into common pathways and complex relationships among immune-mediated diseases
- (2013) Miles Parkes et al. NATURE REVIEWS GENETICS
- JAKs and STATs in Immunity, Immunodeficiency, and Cancer
- (2013) John J. O'Shea et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study
- (2012) Mark C Genovese et al. ANNALS OF THE RHEUMATIC DISEASES
- Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis
- (2012) Lotta Utriainen et al. ARTHRITIS AND RHEUMATISM
- Motion for debate: The development of ankylosis in ankylosing spondylitis is largely dependent on inflammation
- (2012) Walter P. Maksymowych et al. ARTHRITIS AND RHEUMATISM
- β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice
- (2012) Merja Ruutu et al. ARTHRITIS AND RHEUMATISM
- Seventeen in Crohn's disease: less prime than we thought?
- (2012) Tim Raine et al. GUT
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- Levels of Circulating Th17 Cells and Regulatory T Cells in Ankylosing Spondylitis Patients with an Inadequate Response to Anti−TNF-α Therapy
- (2012) Li Xueyi et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Endoplasmic Reticulum Stress Regulates the Innate Immunity Critical Transcription Factor IRF3
- (2012) Yi-Ping Liu et al. JOURNAL OF IMMUNOLOGY
- Cytokine Secretion by Pathogen Recognition Receptor-stimulated Dendritic Cells in Rheumatoid Arthritis and Ankylosing Spondylitis
- (2012) C. PREVOSTO et al. JOURNAL OF RHEUMATOLOGY
- Association of serum interleukin-17 and interleukin-23 levels with disease activity in Chinese patients with ankylosing spondylitis
- (2012) Wei-Sheng Chen et al. Journal of the Chinese Medical Association
- Induction and molecular signature of pathogenic TH17 cells
- (2012) Youjin Lee et al. NATURE IMMUNOLOGY
- IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells
- (2012) Jonathan P Sherlock et al. NATURE MEDICINE
- Targeting IL-17 and TH17 cells in chronic inflammation
- (2012) Pierre Miossec et al. NATURE REVIEWS DRUG DISCOVERY
- Developments in therapies for spondyloarthritis
- (2012) Joachim Sieper Nature Reviews Rheumatology
- Genetics of spondyloarthritis—beyond the MHC
- (2012) John D. Reveille Nature Reviews Rheumatology
- Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
- (2012) Kim A. Papp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease
- (2012) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis
- (2012) Yumiko Wada et al. PLoS One
- Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis
- (2012) Lei Zhang et al. PLoS One
- The mystery of missing heritability: Genetic interactions create phantom heritability
- (2012) O. Zuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genetics of Ankylosing Spondylitis and Axial Spondyloarthritis
- (2012) Philip C. Robinson et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Decreased Th17 and Th1 cells in the peripheral blood of patients with early non-radiographic axial spondyloarthritis: a marker of disease activity in HLA-B27+ patients
- (2012) M.-B. Bautista-Caro et al. RHEUMATOLOGY
- Prevalence of axial spondylarthritis in the United States: Estimates from a cross-sectional survey
- (2012) John D. Reveille et al. ARTHRITIS CARE & RESEARCH
- Ankylosing spondylitis macrophage production of higher levels of interleukin-23 in response to lipopolysaccharide without induction of a significant unfolded protein response
- (2011) Ling Zeng et al. ARTHRITIS AND RHEUMATISM
- Time for a gut check: Evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome
- (2011) James T. Rosenbaum et al. ARTHRITIS AND RHEUMATISM
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- (2011) P. Bowness et al. JOURNAL OF IMMUNOLOGY
- Spondyloarthritis
- (2011) Maxime Dougados et al. LANCET
- A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis
- (2011) Zhiming Lin et al. NATURE GENETICS
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- (2011) David M Evans et al. NATURE GENETICS
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- (2011) Paola Di Meglio et al. PLoS One
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- (2011) Kamran Ghoreschi et al. TRENDS IN IMMUNOLOGY
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- (2011) Heiner Appel et al. ARTHRITIS RESEARCH & THERAPY
- The Assessment of SpondyloArthritis international Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general
- (2010) M. Rudwaleit et al. ANNALS OF THE RHEUMATIC DISEASES
- Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis
- (2010) Yang Mei et al. CLINICAL RHEUMATOLOGY
- Imbalance of NKp44+NKp46− and NKp44−NKp46+ Natural Killer Cells in the Intestinal Mucosa of Patients With Crohn's Disease
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- (2010) J J Pointon et al. GENES AND IMMUNITY
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- (2010) K. Boniface et al. JOURNAL OF IMMUNOLOGY
- XBP-1 Couples Endoplasmic Reticulum Stress to Augmented IFN- Induction via a cis-Acting Enhancer in Macrophages
- (2010) L. Zeng et al. JOURNAL OF IMMUNOLOGY
- Frequency and Phenotype of T Helper 17 Cells in Peripheral Blood and Synovial Fluid of Patients with Reactive Arthritis
- (2010) H. SHEN et al. JOURNAL OF RHEUMATOLOGY
- Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
- (2010) John D Reveille et al. NATURE GENETICS
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
- (2010) Jane C. Goodall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells
- (2010) J. J. O'Shea et al. SCIENCE
- Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease
- (2010) Patrick Danoy et al. PLoS Genetics
- The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection
- (2009) M Rudwaleit et al. ANNALS OF THE RHEUMATIC DISEASES
- Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis
- (2009) L. Melis et al. ANNALS OF THE RHEUMATIC DISEASES
- Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
- (2009) Hui Shen et al. ARTHRITIS AND RHEUMATISM
- Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability
- (2009) Maarten Dhaenens et al. ARTHRITIS AND RHEUMATISM
- Spondylarthritis in HLA-B27/human β2-microglobulin-transgenic rats is not prevented by lack of CD8
- (2009) Joel D. Taurog et al. ARTHRITIS AND RHEUMATISM
- HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats
- (2009) Monica L. DeLay et al. ARTHRITIS AND RHEUMATISM
- Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis
- (2009) Francesco Ciccia et al. ARTHRITIS AND RHEUMATISM
- Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population
- (2009) Stuart I. Davidson et al. ARTHRITIS AND RHEUMATISM
- Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells
- (2009) Raymond E. Eid et al. CIRCULATION
- Late Developmental Plasticity in the T Helper 17 Lineage
- (2009) Yun Kyung Lee et al. IMMUNITY
- Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
- (2009) Caroline E. Sutton et al. IMMUNITY
- From HLA-B27 to spondyloarthritis: a journey through the ER
- (2009) Robert A. Colbert et al. IMMUNOLOGICAL REVIEWS
- IL-23R Polymorphisms in Patients with Ankylosing Spondylitis in Korea
- (2009) I.-H. SUNG et al. JOURNAL OF RHEUMATOLOGY
- Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial
- (2009) Alice Gottlieb et al. LANCET
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
- (2009) Mandy J McGeachy et al. NATURE IMMUNOLOGY
- Interleukin-17 and Type 17 Helper T Cells
- (2009) Pierre Miossec et al. NEW ENGLAND JOURNAL OF MEDICINE
- Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
- (2008) Camilla Jandus et al. ARTHRITIS AND RHEUMATISM
- Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-γ dysregulation
- (2008) Judith A. Smith et al. ARTHRITIS AND RHEUMATISM
- The interleukin-23/interleukin-17 axis in spondyloarthritis
- (2008) Gerlinde Layh-Schmitt et al. CURRENT OPINION IN RHEUMATOLOGY
- Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-β inductionvia X-box binding protein 1
- (2008) Judith A. Smith et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
- (2008) Lauren A. Zenewicz et al. IMMUNITY
- Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
- (2008) Craig L Leonardi et al. LANCET
- Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
- (2008) Kim A Papp et al. LANCET
- Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
- (2008) Joshua D. Milner et al. NATURE
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