NLRP3 Inflammasome Involves in the Acute Exacerbation of Patients with Chronic Obstructive Pulmonary Disease

The Nucleotide-Binding Oligomerization Domain–Like Receptor Family Pyrin Domain-Containing 3 Inflammasome Regulates Bronchial Epithelial Cell Injury and Proapoptosis after Exposure to Biomass Fuel Smoke

(2016) Chen Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inflammasomes in COPD and neutrophilic asthma

(2015) Richard Y Kim et al.   THORAX

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome

(2015) Jose L. Nieto-Torres et al.   VIROLOGY

Quantitative analysis of pathogens in the lower respiratory tract of patients with chronic obstructive pulmonary disease

(2015) Huaying Wang et al.   BMC Pulmonary Medicine

The role of the NLRP3 inflammasome in pulmonary diseases

(2015) Nima Hosseinian et al.   Therapeutic Advances in Respiratory Disease

Functional relevance of NLRP3 inflammasome-mediated interleukin (IL)-1β during acute allergic airway inflammation

(2014) M. Ritter et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Probenecid reduces infection and inflammation in acute Pseudomonas aeruginosa pneumonia

(2014) Bodo Wonnenberg et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

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(2014) Susanne Dihlmann et al.   MOLECULAR MEDICINE

Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

(2014) Salik Hussain et al.   Particle and Fibre Toxicology

Role of the Inflammasome-Caspase1/11-IL-1/18 Axis in Cigarette Smoke Driven Airway Inflammation: An Insight into the Pathogenesis of COPD

(2014) Suffwan Eltom et al.   PLoS One

New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease

(2013) Dominic De Nardo et al.   AMERICAN JOURNAL OF PATHOLOGY

Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β — A Possible Pathway of Exacerbations in COPD

(2013) Johannes Rotta detto Loria et al.   PLoS One

Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner

(2012) Magali Perret et al.   CELLULAR MICROBIOLOGY

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

A Potential Role for P2X7R in Allergic Airway Inflammation in Mice and Humans

(2010) Tobias Müller et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF- B Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor

(2009) J. Harder et al.   JOURNAL OF IMMUNOLOGY

Interleukin-18 in induced sputum: Association with lung function in chronic obstructive pulmonary disease

(2009) Nikoletta Rovina et al.   RESPIRATORY MEDICINE

The Pathology of Chronic Obstructive Pulmonary Disease

(2008) James C. Hogg et al.   Annual Review of Pathology-Mechanisms of Disease

Interleukin-18 production and pulmonary function in COPD

(2007) H. Imaoka et al.   EUROPEAN RESPIRATORY JOURNAL