Role of the Inflammasome-Caspase1/11-IL-1/18 Axis in Cigarette Smoke Driven Airway Inflammation: An Insight into the Pathogenesis of COPD

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

(2014) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Role of IL-18 in Second-Hand Smoke–Induced Emphysema

(2013) Adelheid Kratzer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-18 Induces Emphysema and Airway and Vascular Remodeling via IFN-γ, IL-17A, and IL-13

(2012) Min-Jong Kang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proinflammatory Cytokines Induce Bronchial Hyperplasia and Squamous Metaplasia in Smokers

(2012) Michael Herfs et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Increased Expression of Interleukin-18 and its Receptor in Peripheral Blood of Patients with Chronic Obstructive Pulmonary Disease

(2012) Jianmiao Wang et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Association of interleukin-18 promoter polymorphisms with chronic obstructive pulmonary disease in male smokers

(2012) J. Wang et al.   International Journal of Immunogenetics

Caspase-4 Is Required for Activation of Inflammasomes

(2012) G. Sollberger et al.   JOURNAL OF IMMUNOLOGY

Role of IL-1  and the Nlrp3/caspase-1/IL-1  axis in cigarette smoke-induced pulmonary inflammation and COPD

(2011) N. S. Pauwels et al.   EUROPEAN RESPIRATORY JOURNAL

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

(2011) Suffwan Eltom et al.   PLoS One

IL-1α/IL-1R1 Expression in Chronic Obstructive Pulmonary Disease and Mechanistic Relevance to Smoke-Induced Neutrophilia in Mice

(2011) Fernando M. Botelho et al.   PLoS One

Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice

(2011) Frank Silva Bezerra et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Extracellular Adenosine Triphosphate and Chronic Obstructive Pulmonary Disease

(2010) Marek Lommatzsch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

P2X7Receptor Signaling in the Pathogenesis of Smoke-Induced Lung Inflammation and Emphysema

(2010) Monica Lucattelli et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Cytotoxic Potential of Lung CD8+ T Cells Increases with Chronic Obstructive Pulmonary Disease Severity and with In Vitro Stimulation by IL-18 or IL-15

(2010) C. M. Freeman et al.   JOURNAL OF IMMUNOLOGY

Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema

(2010) S. Cicko et al.   JOURNAL OF IMMUNOLOGY

Imbalances Between Interleukin-1 and Tumor Necrosis Factor Agonists and Antagonists in Stable COPD

(2009) Elizabeth Sapey et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Interleukin-18 in induced sputum: Association with lung function in chronic obstructive pulmonary disease

(2009) Nikoletta Rovina et al.   RESPIRATORY MEDICINE

The Role of Interleukin-1β in Murine Cigarette Smoke–Induced Emphysema and Small Airway Remodeling

(2008) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke

(2008) C Le Quément et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polymorphisms in interleukin-1B and its receptor antagonist genes and the risk of chronic obstructive pulmonary disease in a Korean population: a case–control study

(2008) Jong Myung Lee et al.   RESPIRATORY MEDICINE

Interleukin-18 production and pulmonary function in COPD

(2007) H. Imaoka et al.   EUROPEAN RESPIRATORY JOURNAL