Development of mucosal-associated invariant T cells

Human blood MAIT cell subsets defined using MR1 tetramers

(2018) Nicholas A Gherardin et al.   IMMUNOLOGY AND CELL BIOLOGY

An overview on the identification of MAIT cell antigens

(2018) Lars Kjer-Nielsen et al.   IMMUNOLOGY AND CELL BIOLOGY

MAIT cells and viruses

(2018) James E Ussher et al.   IMMUNOLOGY AND CELL BIOLOGY

Mucosal-associated invariant T cells in autoimmune and immune-mediated diseases

(2018) Ophélie Rouxel et al.   IMMUNOLOGY AND CELL BIOLOGY

MAIT cells and microbial immunity

(2018) Erin W Meermeier et al.   IMMUNOLOGY AND CELL BIOLOGY

Ontogeny of human mucosal-associated invariant T cells and related T cell subsets

(2018) Ghada Ben Youssef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-7 Availability Is Maintained by a Hematopoietic Cytokine Sink Comprising Innate Lymphoid Cells and T Cells

(2017) Christopher E. Martin et al.   IMMUNITY

Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines

(2017) Joana Dias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

(2016) Nicholas A. Gherardin et al.   IMMUNITY

Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity

(2016) Joana Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation

(2016) A Gibbs et al.   Mucosal Immunology

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

(2016) Z Chen et al.   Mucosal Immunology

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

(2016) Hui-Fern Koay et al.   NATURE IMMUNOLOGY

miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling

(2016) Maya Fedeli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

(2016) Charis E. Teh et al.   Nature Communications

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

(2016) Erin W. Meermeier et al.   Nature Communications

Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

(2015) Sidonia B. G. Eckle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mucosal-associated invariant T cell–rich congenic mouse strain allows functional evaluation

(2015) Yue Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

(2015) Azad Rahimpour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PLZF Controls the Development of Fetal-Derived IL-17+Vγ6+γδ T Cells

(2015) Ying Lu et al.   JOURNAL OF IMMUNOLOGY

Molecular Analyses Define Vα7.2-Jα33+ MAIT Cell Depletion in HIV Infection

(2015) James E. Ussher et al.   MEDICINE

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function

(2015) Leonid A Pobezinsky et al.   NATURE IMMUNOLOGY

PLZF expression maps the early stages of ILC1 lineage development

(2015) Michael G. Constantinides et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection

(2015) Edwin Leeansyah et al.   PLoS Pathogens

Biology of CD1- and MR1-Restricted T Cells

(2014) Mariolina Salio et al.   Annual Review of Immunology

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

(2014) Caroline S Fernandez et al.   IMMUNOLOGY AND CELL BIOLOGY

E and Id Proteins Influence Invariant NKT Cell Sublineage Differentiation and Proliferation

(2014) L. M. D'Cruz et al.   JOURNAL OF IMMUNOLOGY

IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival

(2014) K E Webster et al.   Mucosal Immunology

MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

(2014) A Kurioka et al.   Mucosal Immunology

A committed precursor to innate lymphoid cells

(2014) Michael G. Constantinides et al.   NATURE

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

The Decrease in Number and Change in Phenotype of Mucosal-Associated Invariant T cells in the Elderly and Differences in Men and Women of Reproductive Age

(2014) J. Novak et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Rise and Fall of MAIT Cells with Age

(2014) L. J. Walker et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

(2014) Marco Lepore et al.   Nature Communications

Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development

(2014) Edwin Leeansyah et al.   Nature Communications

SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors

(2014) Jaime De Calisto et al.   Frontiers in Immunology

The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis

(2013) Jorge Henao-Mejia et al.   IMMUNITY

Causes, consequences, and reversal of immune system aging

(2013) Encarnacion Montecino-Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

(2013) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Double Positive Thymocytes Select Mucosal-Associated Invariant T Cells

(2013) N. Seach et al.   JOURNAL OF IMMUNOLOGY

Essential Functions for ID Proteins at Multiple Checkpoints in Invariant NKT Cell Development

(2013) M. Verykokakis et al.   JOURNAL OF IMMUNOLOGY

IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

(2013) X.-Z. Tang et al.   JOURNAL OF IMMUNOLOGY

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

(2013) A. Meierovics et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Gracefully Aging Immune System

(2013) D. Boraschi et al.   Science Translational Medicine

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

(2012) E. Leeansyah et al.   BLOOD

Early and nonreversible decrease of CD161++/MAIT cells in HIV infection

(2012) C. Cosgrove et al.   BLOOD

Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals

(2012) Kentaro Tsukamoto et al.   IMMUNOGENETICS

MicroRNA miR-150 Is Involved in V 14 Invariant NKT Cell Development and Function

(2012) Q. Zheng et al.   JOURNAL OF IMMUNOLOGY

Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress

(2012) M C Gold et al.   Mucosal Immunology

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

Human MAIT and CD8   cells develop from a pool of type-17 precommitted CD8+ T cells

(2011) L. J. Walker et al.   BLOOD

Endogenous MHC-Related Protein 1 Is Transiently Expressed on the Plasma Membrane in a Conformation That Activates Mucosal-Associated Invariant T Cells

(2011) W.-J. Chua et al.   JOURNAL OF IMMUNOLOGY

Mucosal-associated invariant T cells: unconventional development and function

(2011) Lionel Le Bourhis et al.   TRENDS IN IMMUNOLOGY

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Transcriptional control of invariant NKT cell development

(2010) Rupali Das et al.   IMMUNOLOGICAL REVIEWS

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells

(2010) Louise M D'Cruz et al.   NATURE IMMUNOLOGY

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

Natural Killer T Cells and Autoimmune Disease

(2009) Lan Wu et al.   CURRENT MOLECULAR MEDICINE

Dicer-Dependent MicroRNA Pathway Controls Invariant NKT Cell Development

(2009) M. Fedeli et al.   JOURNAL OF IMMUNOLOGY

Transcriptional regulator Id2 controls survival of hepatic NKT cells

(2009) L. A. Monticelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of    T cells with restricted TCR diversity

(2009) T. Kreslavsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stepwise Development of MAIT Cells in Mouse and Human

(2009) Emmanuel Martin et al.   PLOS BIOLOGY

The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage

(2008) Adam K. Savage et al.   IMMUNITY

The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

(2008) Damian Kovalovsky et al.   NATURE IMMUNOLOGY