The Gracefully Aging Immune System

Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination

(2013) A. Szakacs et al.   NEUROLOGY

Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis

(2013) E. Miller et al.   BMJ-British Medical Journal

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death

(2012) Stefan Brunner et al.   AGING CELL

Vaccines for the elderly

(2012) B. Weinberger et al.   CLINICAL MICROBIOLOGY AND INFECTION

Chronic inflammation and aging: DNA damage tips the balance

(2012) Mary M Cavanagh et al.   CURRENT OPINION IN IMMUNOLOGY

Immunosenescence and HIV

(2012) Steven G Deeks et al.   CURRENT OPINION IN IMMUNOLOGY

Pneumococcal Polysaccharide Conjugate Vaccine (13-Valent, Adsorbed)

(2012) Lesley J. Scott et al.   DRUGS & AGING

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

(2012) Evan W. Newell et al.   IMMUNITY

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Age-Associated Changes in MicroRNA Expression in Bone Marrow Derived Dendritic Cells

(2012) Seungbum Park et al.   IMMUNOLOGICAL INVESTIGATIONS

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

(2012) Guangjin Li et al.   NATURE MEDICINE

AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

(2012) Hanna Nohynek et al.   PLoS One

Host Immune Transcriptional Profiles Reflect the Variability in Clinical Disease Manifestations in Patients with Staphylococcus aureus Infections

(2012) Romain Banchereau et al.   PLoS One

Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age

(2012) P. L. F. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age

(2012) M. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADITEC: Joining Forces for Next-Generation Vaccines

(2012) R. Rappuoli et al.   Science Translational Medicine

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

Clostridium difficile: Development of a novel candidate vaccine

(2012) Ginamarie Foglia et al.   VACCINE

Age-Related Changes in Human Peripheral Blood IGH Repertoire Following Vaccination

(2012) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china

(2011) Fang Han et al.   ANNALS OF NEUROLOGY

Dendritic cells and aging: consequences for autoimmunity

(2011) Anshu Agrawal et al.   Expert Review of Clinical Immunology

MF59 adjuvant: the best insurance against influenza strain diversity

(2011) Derek T O’Hagan et al.   Expert Review of Vaccines

Dissecting the human immunologic memory for pathogens

(2011) Christina E. Zielinski et al.   IMMUNOLOGICAL REVIEWS

Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

(2011) Sanae Sasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

The impact of aging on memory T cell phenotype and function in the human bone marrow

(2011) Dietmar Herndler-Brandstetter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

(2011) Peng Qiu et al.   NATURE BIOTECHNOLOGY

Systems Vaccinomics: The Road Ahead for Vaccinology

(2011) Alan Bernstein et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

An Exhaustive, Non-Euclidean, Non-Parametric Data Mining Tool for Unraveling the Complexity of Biological Systems – Novel Insights into Malaria

(2011) Cheikh Loucoubar et al.   PLoS One

High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment

(2011) A. C. Logan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Safety, tolerability, and immunogenicity after 1 and 2 doses of zoster vaccine in healthy adults ≥60 years of age

(2011) Joost N. Vermeulen et al.   VACCINE

Zoster Vaccine: Current Status and Future Prospects

(2010) Michael N. Oxman   CLINICAL INFECTIOUS DISEASES

Immune memory and aging: an infinite or finite resource?

(2010) Janko Nikolich-Žugich et al.   CURRENT OPINION IN IMMUNOLOGY

Aging of the innate immune system

(2010) Albert C Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

Tetanus seroepidemiology and factors influencing immunity status among farmers of advanced age

(2010) Serkan Öncü et al.   HEALTH POLICY

Plasmablast-derived polyclonal antibody response after influenza vaccination

(2010) Xiao-Song He et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Adenosine Deaminase Modulation of Telomerase Activity and Replicative Senescence in Human CD8 T Lymphocytes

(2010) S. T. Parish et al.   JOURNAL OF IMMUNOLOGY

Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

(2010) Alexander Panda et al.   JOURNAL OF IMMUNOLOGY

Body Mass Index and Survival in Men and Women Aged 70 to 75

(2010) Leon Flicker et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Ageing and immunity

(2010) Diana Boraschi et al.   VACCINE

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis

(2009) Lan Shao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Decreased TNF-α synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+T cells during aging

(2009) Elaine Agius et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccine Prevention of Maternal Cytomegalovirus Infection

(2009) Robert F. Pass et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telomerase insufficiency in rheumatoid arthritis

(2009) H. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human innate immunosenescence: causes and consequences for immunity in old age

(2009) Alexander Panda et al.   TRENDS IN IMMUNOLOGY

Intradermal influenza vaccine for older adults: A randomized controlled multicenter phase III study

(2009) Robert Arnou et al.   VACCINE

B-cell diversity decreases in old age and is correlated with poor health status

(2008) Kate L. Gibson et al.   AGING CELL

The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo

(2008) Milica Vukmanovic-Stejic et al.   JOURNAL OF CLINICAL INVESTIGATION

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY