COPII-dependent ER export in animal cells: adaptation and control for diverse cargo

Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion

(2018) Kohei Kawaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane Transport at an Organelle Interface in the Early Secretory Pathway: Take Your Coat Off and Stay a While

(2018) Michael G. Hanna et al.   BIOESSAYS

SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization

(2018) Keiko Saegusa et al.   JOURNAL OF CELL BIOLOGY

Dimeric sorting code for concentrative cargo selection by the COPII coat

(2018) Chao Nie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

(2018) Tsung-Li Liu et al.   SCIENCE

TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes

(2018) Ishier Raote et al.   eLife

COPII-coated membranes function as transport carriers of intracellular procollagen I

(2017) Amita Gorur et al.   JOURNAL OF CELL BIOLOGY

UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage–specific manner

(2017) Tokiro Ishikawa et al.   JOURNAL OF CELL BIOLOGY

TANGO1 recruits Sec16 to coordinately organize ER exit sites for efficient secretion

(2017) Miharu Maeda et al.   JOURNAL OF CELL BIOLOGY

Tango1 spatially organizes ER exit sites to control ER export

(2017) Min Liu et al.   JOURNAL OF CELL BIOLOGY

TANGO1 assembles into rings around COPII coats at ER exit sites

(2017) Ishier Raote et al.   JOURNAL OF CELL BIOLOGY

Microscopy analysis of reconstituted COPII coat polymerization and Sec16 dynamics

(2017) Hirohiko Iwasaki et al.   JOURNAL OF CELL SCIENCE

TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER–Golgi intermediate compartments

(2017) Michael G. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual function for Tango1 in secretion of bulky cargo and in ER-Golgi morphology

(2017) L. D. Ríos-Barrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone

(2017) Shinya Ito et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity

(2017) Ashley J. Evans et al.   Cell Reports

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments

(2017) Svetlana O Dodonova et al.   eLife

Cargo Capture and Bulk Flow in the Early Secretory Pathway

(2016) Charles Barlowe et al.   Annual Review of Cell and Developmental Biology

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor

(2016) Colleen A. McGourty et al.   CELL

The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein

(2016) Takashi Kanadome et al.   FEBS Journal

The G1Cyclin-dependent Kinase CRK1 inTrypanosoma bruceiRegulates Anterograde Protein Transport by Phosphorylating the COPII Subunit Sec31

(2016) Huiqing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum

(2016) António J.M. Santos et al.   JOURNAL OF CELL BIOLOGY

An unrecognized function for COPII components in recruiting the viral replication protein BMV 1a to the perinuclear ER

(2016) Jianhui Li et al.   JOURNAL OF CELL SCIENCE

Inhibition of cargo export at ER exit sites and the trans-Golgi network by the secretion inhibitor FLI-06

(2016) Yoji Yonemura et al.   JOURNAL OF CELL SCIENCE

Sec24C/D-isoform–specific sorting of the preassembled ER–Golgi Q-SNARE complex

(2016) Frank Adolf et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct isoform-specific complexes of TANGO1 cooperatively facilitate collagen secretion from the endoplasmic reticulum

(2016) Miharu Maeda et al.   MOLECULAR BIOLOGY OF THE CELL

Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules

(2016) Yoshihiro Ishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of COPII Vesicles Indicates a Role for the Emp47-Ssp120 Complex in Transport of Cell Surface Glycoproteins

(2016) Neil G. Margulis et al.   TRAFFIC

COPII Paralogs in Plants: Functional Redundancy or Diversity?

(2016) Kin Pan Chung et al.   TRENDS IN PLANT SCIENCE

Sec16 alternative splicing dynamically controls COPII transport efficiency

(2016) Ilka Wilhelmi et al.   Nature Communications

Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis

(2016) Haeryung Lee et al.   Nature Communications

TFG Promotes Organization of Transitional ER and Efficient Collagen Secretion

(2016) Janine McCaughey et al.   Cell Reports

An ER-Localized SNARE Protein Is Exported in Specific COPII Vesicles for Autophagosome Biogenesis

(2016) Leticia Lemus et al.   Cell Reports

Sec24 phosphorylation regulates autophagosome abundance during nutrient deprivation

(2016) Saralin Davis et al.   eLife

Penta-EF-Hand Protein Peflin Is a Negative Regulator of ER-To-Golgi Transport

(2016) Mariah Rayl et al.   PLoS One

Mutations in SEC24D, Encoding a Component of the COPII Machinery, Cause a Syndromic Form of Osteogenesis Imperfecta

(2015) Lutz Garbes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer

(2015) Lamis Yehia et al.   AMERICAN JOURNAL OF HUMAN GENETICS

NBAS mutations cause a multisystem disorder involving bone, connective tissue, liver, immune system, and retina

(2015) Nuria Garcia Segarra et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Host endoplasmic reticulum COPII proteins control cell-to-cell spread of the bacterial pathogenListeria monocytogenes

(2015) Antonella Gianfelice et al.   CELLULAR MICROBIOLOGY

The COPII complex and lysosomal VAMP7 determine intracellularSalmonellalocalization and growth

(2015) José Carlos Santos et al.   CELLULAR MICROBIOLOGY

Sec24 Is a Coincidence Detector that Simultaneously Binds Two Signals to Drive ER Export

(2015) Silvere Pagant et al.   CURRENT BIOLOGY

TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization

(2015) A. Johnson et al.   EMBO JOURNAL

Unexpected Ancient Paralogs and an Evolutionary Model for the COPII Coat Complex

(2015) Alexander Schlacht et al.   Genome Biology and Evolution

The Vesicle-Forming 6K2Protein of Turnip Mosaic Virus Interacts with the COPII Coatomer Sec24a for Viral Systemic Infection

(2015) Jun Jiang et al.   JOURNAL OF VIROLOGY

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

(2015) Daniela Stadel et al.   MOLECULAR CELL

Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export inArabidopsis thaliana

(2015) Yonglun Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice

(2015) Min Zhu et al.   Scientific Reports

A requirement for ER-derived COPII vesicles in phagophore initiation

(2014) Juan Wang et al.   Autophagy

Apoptosis-linked Gene-2 (ALG-2)/Sec31 Interactions Regulate Endoplasmic Reticulum (ER)-to-Golgi Transport

(2014) Jared R. Helm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export

(2014) Kota Saito et al.   JOURNAL OF CELL BIOLOGY

A cascade of ER exit site assembly that is regulated by p125A and lipid signals

(2014) D. Klinkenberg et al.   JOURNAL OF CELL SCIENCE

Absence of a Red Blood Cell Phenotype in Mice with Hematopoietic Deficiency of SEC23B

(2014) R. Khoriaty et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulated Oligomerization Induces Uptake of a Membrane Protein into COPII Vesicles Independent of Its Cytosolic Tail

(2014) Sebastian Springer et al.   TRAFFIC

A stress assembly that confers cell viability by preserving ERES components during amino-acid starvation

(2014) Margarita Zacharogianni et al.   eLife

SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

(2014) Cristina Nogueira et al.   eLife

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

(2014) Liang Ge et al.   eLife

COPII — a flexible vesicle formation system

(2013) Elizabeth A Miller et al.   CURRENT OPINION IN CELL BIOLOGY

Endoplasmic Reticulum stress reduces COPII vesicle formation and modifies Sec23a cycling at ERESs

(2013) Giuseppina Amodio et al.   FEBS LETTERS

Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesis

(2013) T. J. Satchwell et al.   HAEMATOLOGICA

Mutations in the COPII Vesicle Component GeneSEC24Bare Associated with Human Neural Tube Defects

(2013) Xue-Yan Yang et al.   HUMAN MUTATION

A role for endoplasmic reticulum exit sites in foot-and-mouth disease virus infection

(2013) R. Midgley et al.   JOURNAL OF GENERAL VIROLOGY

The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection

(2013) Ajitha Thanabalasuriar et al.   MICROBES AND INFECTION

COPII machinery cooperates with ER-localized Hsp40 to sequester misfolded membrane proteins into ER-associated compartments

(2013) Shogo Kakoi et al.   MOLECULAR BIOLOGY OF THE CELL

Sec16 influences transitional ER sites by regulating rather than organizing COPII

(2013) Nike Bharucha et al.   MOLECULAR BIOLOGY OF THE CELL

Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits

(2013) Deepali Bhandari et al.   MOLECULAR BIOLOGY OF THE CELL

Chondrocyte Proliferation Regulated by Secreted Luminal Domain of ER Stress Transducer BBF2H7/CREB3L2

(2013) Atsushi Saito et al.   MOLECULAR CELL

CK2 Phosphorylates Sec31 and Regulates ER-To-Golgi Trafficking

(2013) Mayuko Koreishi et al.   PLoS One

ALG-2 Attenuates COPII Budding In Vitro and Stabilizes the Sec23/Sec31A Complex

(2013) Jonas M. la Cour et al.   PLoS One

The Highly Conserved COPII Coat Complex Sorts Cargo from the Endoplasmic Reticulum and Targets It to the Golgi

(2013) C. Lord et al.   Cold Spring Harbor Perspectives in Biology

The structure of the COPII transport-vesicle coat assembled on membranes

(2013) Giulia Zanetti et al.   eLife

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion

(2013) Xiao-Wei Chen et al.   eLife

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion

(2012) A. K. Townley et al.   JOURNAL OF CELL SCIENCE

BBF2H7-Mediated Sec23A Pathway Is Required for Endoplasmic Reticulum-to-Golgi Trafficking in Dermal Fibroblasts to Promote Collagen Synthesis

(2012) Seiko Ishikura-Kinoshita et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Poliovirus Infection Transiently Increases COPII Vesicle Budding

(2012) Meg Trahey et al.   JOURNAL OF VIROLOGY

Insights into structural and regulatory roles of Sec16 in COPII vesicle formation at ER exit sites

(2012) Tomohiro Yorimitsu et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin-dependent regulation of COPII coat size and function

(2012) Lingyan Jin et al.   NATURE

A pseudoatomic model of the COPII cage obtained from cryo-electron microscopy and mass spectrometry

(2012) Alex J Noble et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sec12 Binds to Sec16 at Transitional ER Sites

(2012) Elisabeth A. Montegna et al.   PLoS One

Involvement of the Penta-EF-Hand Protein Pef1p in the Ca2+-Dependent Regulation of COPII Subunit Assembly in Saccharomyces cerevisiae

(2012) Mariko Yoshibori et al.   PLoS One

Sedlin Controls the ER Export of Procollagen by Regulating the Sar1 Cycle

(2012) R. Venditti et al.   SCIENCE

ER Cargo Properties Specify a Requirement for COPII Coat Rigidity Mediated by Sec13p

(2012) A. Copic et al.   SCIENCE

A Systematic Approach to Pair Secretory Cargo Receptors with Their Cargo Suggests a Mechanism for Cargo Selection by Erv14

(2012) Yonatan Herzig et al.   PLOS BIOLOGY

Insertional mutation in the Golgb1 gene is associated with osteochondrodysplasia and systemic edema in the OCD rat

(2011) Kentaro Katayama et al.   BONE

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

(2011) D. B. Melville et al.   Disease Models & Mechanisms

Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat

(2011) Leslie F Kung et al.   EMBO JOURNAL

p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis

(2011) Nagisa Arimitsu et al.   FEBS LETTERS

Global defects in collagen secretion in aMia3/TANGO1knockout mouse

(2011) Deanna G. Wilson et al.   JOURNAL OF CELL BIOLOGY

cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites

(2011) Kota Saito et al.   MOLECULAR BIOLOGY OF THE CELL

Sequential interactions with Sec23 control the direction of vesicle traffic

(2011) Christopher Lord et al.   NATURE

TFG-1 function in protein secretion and oncogenesis

(2011) Kristen Witte et al.   NATURE CELL BIOLOGY

COPII and the regulation of protein sorting in mammals

(2011) Giulia Zanetti et al.   NATURE CELL BIOLOGY

Multibudded tubules formed by COPII on artificial liposomes

(2011) Kirsten Bacia et al.   Scientific Reports

Biogenesis of the plant Golgi apparatus

(2010) Chris Hawes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The ALG-2 Binding Site in Sec31A Influences the Retention Kinetics of Sec31A at the Endoplasmic Reticulum Exit Sites as Revealed by Live-Cell Time-Lapse Imaging

(2010) Hideki SHIBATA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

(2010) C. Wansleeben et al.   DEVELOPMENT

sec24d encoding a component of COPII is essential for vertebra formation, revealed by the analysis of the medaka mutant, vbi

(2010) Satoshi Ohisa et al.   DEVELOPMENTAL BIOLOGY

Structure of the Sec13–Sec16 edge element, a template for assembly of the COPII vesicle coat

(2010) James R.R. Whittle et al.   JOURNAL OF CELL BIOLOGY

p125A exists as part of the mammalian Sec13/Sec31 COPII subcomplex to facilitate ER-Golgi transport

(2010) Yan Shan Ong et al.   JOURNAL OF CELL BIOLOGY

Lethal Skeletal Dysplasia in Mice and Humans Lacking the Golgin GMAP-210

(2010) Patrick Smits et al.   NEW ENGLAND JOURNAL OF MEDICINE

Congenital dyserythropoietic anemia type II (CDAII) is caused by mutations in theSEC23Bgene

(2009) Paola Bianchi et al.   HUMAN MUTATION

Organisation of human ER-exit sites: requirements for the localisation of Sec16 to transitional ER

(2009) H. Hughes et al.   JOURNAL OF CELL SCIENCE

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

(2009) Janna Merte et al.   NATURE CELL BIOLOGY

Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis

(2009) Atsushi Saito et al.   NATURE CELL BIOLOGY

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II

(2009) Klaus Schwarz et al.   NATURE GENETICS

New Insights into the Structural Mechanisms of the COPII Coat

(2009) Christopher Russell et al.   TRAFFIC

Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development

(2008) A. K. Townley et al.   JOURNAL OF CELL SCIENCE

A model for the self-organization of exit sites in the endoplasmic reticulum

(2007) S. Heinzer et al.   JOURNAL OF CELL SCIENCE