Recombinant relaxin protects liver transplants from ischemia damage by hepatocyte glucocorticoid receptor: From bench-to-bedside

Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury

(2017) Shi Yue et al.   JOURNAL OF IMMUNOLOGY

Thrombomodulin Attenuates Inflammatory Damage Due to Liver Ischemia and Reperfusion Injury in Mice in Toll-Like Receptor 4-Dependent Manner

(2016) K. Kadono et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury

(2016) Shi Yue et al.   HEPATOLOGY

Challenges to Liver Transplantation and Strategies to Improve Outcomes

(2015) Philipp Dutkowski et al.   GASTROENTEROLOGY

Analysis of ischemia/reperfusion injury in time-zero biopsies predicts liver allograft outcomes

(2015) Jason M. Ali et al.   LIVER TRANSPLANTATION

High-mobility group box-1 in sterile inflammation

(2014) A. Tsung et al.   JOURNAL OF INTERNAL MEDICINE

Biomarkers distinguish apoptotic and necrotic cell death during hepatic ischemia/reperfusion injury in mice

(2014) Min Yang et al.   LIVER TRANSPLANTATION

Systematic review and meta-analysis of the effect of perioperative steroids on ischaemia-reperfusion injury and surgical stress response in patients undergoing liver resection

(2013) L. A. Orci et al.   BRITISH JOURNAL OF SURGERY

Relaxin has anti-apoptotic effects on human trophoblast-derived HTR-8/SV neo cells

(2013) Romana S.Z. Lodhi et al.   GYNECOLOGICAL ENDOCRINOLOGY

Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertensionin vivo

(2013) Jonathan A. Fallowfield et al.   HEPATOLOGY

Acute treatment with relaxin protects the kidney against ischaemia/reperfusion injury

(2013) Massimo Collino et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Relaxin Family Peptides and Their Receptors

(2013) R. A. D. Bathgate et al.   PHYSIOLOGICAL REVIEWS

Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword

(2013) Amanda Gruver-Yates et al.   Cells

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

(2012) John R Teerlink et al.   LANCET

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

(2012) Yuan Zhai et al.   Nature Reviews Gastroenterology & Hepatology

Relaxin Modulates Proinflammatory Cytokine Secretion from Human Decidual Macrophages1

(2011) J.S. Horton et al.   BIOLOGY OF REPRODUCTION

Relaxin Induces Rapid Dilation of Rodent Small Renal and Human Subcutaneous Arteries via PI3 Kinase and Nitric Oxide

(2011) Jonathan T. McGuane et al.   ENDOCRINOLOGY

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

(2011) Kristina M. Mueller et al.   HEPATOLOGY

Effect of recombinant erythropoietin on ischemia–reperfusion-induced apoptosis in rat liver

(2011) Heba M. Shawky et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Protective effect of methylprednisolone on warm ischemia-reperfusion injury in a cholestatic rat liver

(2010) Gokulakkrishna Subhas et al.   AMERICAN JOURNAL OF SURGERY

Foetal hypoxia increases cardiac AT2R expression and subsequent vulnerability to adult ischaemic injury

(2010) Qin Xue et al.   CARDIOVASCULAR RESEARCH

Relaxin is a candidate drug for lung preservation: Relaxin-induced protection of rat lungs from ischemia-reperfusion injury

(2009) Konstantin Alexiou et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The human glucocorticoid receptor: Molecular basis of biologic function

(2009) Nicolas C. Nicolaides et al.   STEROIDS

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

(2008) Nobuyuki Tamaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL

High mobility group box 1 protein as a marker of hepatocellular injury in human liver transplantation

(2008) Minna Ilmakunnas et al.   LIVER TRANSPLANTATION

RXFP1-inactive relaxin activates human glucocorticoid receptor: Further investigations into the relaxin–GR pathway

(2008) Thomas Dschietzig et al.   REGULATORY PEPTIDES