Acute treatment with relaxin protects the kidney against ischaemia/reperfusion injury

Relaxin improves TNF-α-induced endothelial dysfunction: the role of glucocorticoid receptor and phosphatidylinositol 3-kinase signalling

(2012) Thomas Dschietzig et al.   CARDIOVASCULAR RESEARCH

Acute kidney injury

(2012) Rinaldo Bellomo et al.   LANCET

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

(2012) John R Teerlink et al.   LANCET

Unknown

(2012) Nimesh Patel et al.   MOLECULAR MEDICINE

Previous ischemia and reperfusion injury results in resistance of the kidney against subsequent ischemia and reperfusion insult in mice; a role for the Akt signal pathway

(2012) H.-S. Jang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Timed Maternal Melatonin Treatment Reverses Circadian Disruption of the Fetal Adrenal Clock Imposed by Exposure to Constant Light

(2012) Natalia Mendez et al.   PLoS One

Inhibition of Proinflammatory Cytokines by SCH79797, a Selective Protease-Activated Receptor 1 Antagonist, Protects Rat Kidney Against Ischemia-Reperfusion Injury

(2012) Eman Abdelazeem El Eter et al.   SHOCK

Serum relaxin levels and kidney function in late pregnancy with or without preeclampsia

(2011) R.A. Lafayette et al.   CLINICAL NEPHROLOGY

Relaxin Induces Rapid Dilation of Rodent Small Renal and Human Subcutaneous Arteries via PI3 Kinase and Nitric Oxide

(2011) Jonathan T. McGuane et al.   ENDOCRINOLOGY

Relaxin Ameliorates Hypertension and Increases Nitric Oxide Metabolite Excretion in Angiotensin II But Not N ω -Nitro- l -Arginine Methyl Ester Hypertensive Rats

(2011) Jennifer M. Sasser et al.   HYPERTENSION

Peroxisome proliferator-activated receptor β/δ agonism protects the kidney against ischemia/reperfusion injury in diabetic rats

(2010) Massimo Collino et al.   FREE RADICAL BIOLOGY AND MEDICINE

Membrane receptors: Structure and function of the relaxin family peptide receptors

(2010) Roy C.K. Kong et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Relaxin inhibits early steps in vascular inflammation

(2010) Anna Brecht et al.   REGULATORY PEPTIDES

Relaxin: An Endogenous Renoprotective Factor?

(2009) Tim D. Hewitson et al.   Annals of the New York Academy of Sciences

Scientific Rationale and Design of a Phase I Safety Study of Relaxin in Women with Severe Preeclampsia

(2009) Elaine Unemori et al.   Annals of the New York Academy of Sciences

Relaxin is a candidate drug for lung preservation: Relaxin-induced protection of rat lungs from ischemia-reperfusion injury

(2009) Konstantin Alexiou et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study

(2009) John R Teerlink et al.   LANCET

Relaxin and the progression of kidney disease

(2008) Chrishan S Samuel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Relaxin and Nitric Oxide Signalling

(2008) M. Baccari et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2

(2008) Ishanee Mookerjee et al.   FASEB JOURNAL

Relaxin as a Protective Substance in Preservation Solutions for Organ Transplantation, as Shown in an Isolated Perfused Rat Liver Model

(2008) M.U. Boehnert et al.   TRANSPLANTATION PROCEEDINGS

Relaxin induces mast cell inhibition and reduces ventricular arrhythmias in a swine model of acute myocardial infarction

(2007) Silvia Nistri et al.   PHARMACOLOGICAL RESEARCH