Krüppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease

M2 Kupffer Cells Promote Hepatocyte Senescence

(2014) Jinghong Wan et al.   AMERICAN JOURNAL OF PATHOLOGY

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-κB and signal transducer and activator of transcription 3 pathways

(2014) Shuo Gao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

(2014) J. K. Alder et al.   JOURNAL OF IMMUNOLOGY

Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice

(2014) Meng Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

The liver is populated by a broad spectrum of markers for macrophages. In alcoholic hepatitis the macrophages are M1 and M2

(2013) James Lee et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Role of oxidative stress in the pathogenesis of alcohol-induced liver disease

(2013) B. Sid et al.   FREE RADICAL RESEARCH

M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease

(2013) Jinghong Wan et al.   HEPATOLOGY

Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure

(2013) Kavitha Swaminathan et al.   LIFE SCIENCES

The Identification of CD163 Expressing Phagocytic Chondrocytes in Joint Cartilage and Its Novel Scavenger Role in Cartilage Degradation

(2013) Kai Jiao et al.   PLoS One

Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway

(2013) M Jin et al.   Cell Death & Disease

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone

(2012) Jonas H Graversen et al.   MOLECULAR THERAPY

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4

(2012) Myoung Ok Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors

(2011) K. L. Allen et al.   BLOOD

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

(2011) Alexandre Louvet et al.   HEPATOLOGY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential activation and antagonistic function of HIF-  isoforms in macrophages are essential for NO homeostasis

(2010) N. Takeda et al.   GENES & DEVELOPMENT

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation

(2010) Deepak K Kaushik et al.   Journal of Neuroinflammation

The Etiology of Hepatocellular Carcinoma and Consequences for Treatment

(2010) A. J. Sanyal et al.   ONCOLOGIST

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells

(2010) Simon J. Waddell et al.   PLoS One

Krüppel-like factor 4 regulates adaptive expression of the zinc transporter Zip4 in mouse small intestine

(2009) Juan P. Liuzzi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Opposite Effects of Acute and Chronic Alcohol on Lipopolysaccharide-Induced Inflammation Are Linked to IRAK-M in Human Monocytes

(2009) P. Mandrekar et al.   JOURNAL OF IMMUNOLOGY

Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders

(2009) Jürgen Rehm et al.   LANCET

KLF4 Interacts with  -Catenin/TCF4 and Blocks p300/CBP Recruitment by  -Catenin

(2009) P. M. Evans et al.   MOLECULAR AND CELLULAR BIOLOGY

Alcohol Primes the Airway for Increased Interleukin-13 Signaling

(2008) Patrick O. Mitchell et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

(2008) B. O. Fabriek et al.   BLOOD

Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

(2008) Kihwa Kang et al.   Cell Metabolism

Conditional Deletion of Krüppel-Like Factor 4 Delays Downregulation of Smooth Muscle Cell Differentiation Markers but Accelerates Neointimal Formation Following Vascular Injury

(2008) Tadashi Yoshida et al.   CIRCULATION RESEARCH