HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research

Update on HIV Dementia and HIV-Associated Neurocognitive Disorders

(2014) Bruce J. Brew et al.   Current Neurology and Neuroscience Reports

HIV-1 Entry and Trans-Infection of Astrocytes Involves CD81 Vesicles

(2014) Lachlan R. Gray et al.   PLoS One

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells

(2013) Fiona Wightman et al.   AIDS

Is specific HIV eradication from the brain possible or needed?

(2013) Bruce J Brew et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The search for an HIV cure: tackling latent infection

(2013) Stephen J Kent et al.   LANCET INFECTIOUS DISEASES

Molecular and pathologic insights from latent HIV-1 infection in the human brain

(2013) P. Desplats et al.   NEUROLOGY

The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes

(2013) Lachlan R. Gray et al.   PLoS One

Where does HIV hide? A focus on the central nervous system

(2013) Melissa Churchill et al.   Current Opinion in HIV and AIDS

Comparison of HDAC inhibitors in clinical development

(2013) Thomas Aagaard Rasmussen et al.   Human Vaccines & Immunotherapeutics

Redefining the Viral Reservoirs that Prevent HIV-1 Eradication

(2012) Evelyn Eisele et al.   IMMUNITY

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Shock and kill

(2012) Steven G. Deeks   NATURE

Immune surveillance in the central nervous system

(2012) Shalina S Ousman et al.   NATURE NEUROSCIENCE

The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response

(2011) Wendy Bernhard et al.   FEBS LETTERS

Does use of antiretroviral therapy regimens with high central nervous system penetration improve survival in HIV-infected adults?

(2011) H McManus et al.   HIV MEDICINE

Development of co-selected single nucleotide polymorphisms in the viral promoter precedes the onset of human immunodeficiency virus type 1-associated neurocognitive impairment

(2011) Luna Li et al.   JOURNAL OF NEUROVIROLOGY

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

(2011) S. Xing et al.   JOURNAL OF VIROLOGY

Impact of Non-HIV and HIV Risk Factors on Survival in HIV-Infected Patients on HAART: A Population-Based Nationwide Cohort Study

(2011) Niels Obel et al.   PLoS One

Treatment Intensification Has no Effect on the HIV-1 Central Nervous System Infection in Patients on Suppressive Antiretroviral Therapy

(2010) Aylin Yilmaz et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294

(2010) Kenichi Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

CCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection

(2009) Yujie Liu et al.   Future Microbiology

HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes

(2009) Laetitia Redel et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Modeling HIV persistence, the latent reservoir, and viral blips

(2009) Libin Rong et al.   JOURNAL OF THEORETICAL BIOLOGY

NF-κB: The Inducible Factors of HIV-1 Transcription and their Inhibitors

(2009) Yu Mingyan et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation

(2009) Steven E. Kauder et al.   PLoS Pathogens

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY