HIV-1 Tat Promotes Lysosomal Exocytosis in Astrocytes and Contributes to Astrocyte-mediated Tat Neurotoxicity

HIV-1 Tat Induces Unfolded Protein Response and Endoplasmic Reticulum Stress in Astrocytes and Causes Neurotoxicity through Glial Fibrillary Acidic Protein (GFAP) Activation and Aggregation

(2016) Yan Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increase of transcription factor EB (TFEB) and lysosomes in rat DRG neurons and their transportation to the central nerve terminal in dorsal horn after nerve injury

(2016) J. Jung et al.   NEUROSCIENCE

STAT3 and Its Phosphorylation are Involved in HIV-1 Tat-Induced Transactivation of Glial Fibrillary Acidic Protein

(2015) Yan Fan et al.   CURRENT HIV RESEARCH

Autophagic flux inhibition and lysosomogenesis ensuing cellular capture and retention of the cationic drug quinacrine in murine models

(2015) Alexandre Parks et al.   PeerJ

Macrophage Derived Cystatin B/Cathepsin B in HIV Replication and Neuropathogenesis

(2014) Linda Rivera et al.   CURRENT HIV RESEARCH

Hepatitis C virus (HCV) interaction with astrocytes: nonproductive infection and induction of IL-18

(2014) Ziqing Liu et al.   JOURNAL OF NEUROVIROLOGY

Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders

(2013) Yisel Cantres-Rosario et al.   AIDS

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

(2013) T. P. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Endolysosomes in HIV-1 Tat-Induced Neurotoxicity

(2012) Liang Hui et al.   ASN Neuro

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Role of Cathepsin D in U18666A-induced Neuronal Cell Death

(2012) Asha Amritraj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysregulation of Macrophage-Secreted Cathepsin B Contributes to HIV-1-Linked Neuronal Apoptosis

(2012) Eillen J. Rodriguez-Franco et al.   PLoS One

Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo

(2012) E. R. Bastow et al.   Biology Open

Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

(2011) Qiuli Liang et al.   Molecular Neurodegeneration

Imaging exocytosis of ATP-containing vesicles with TIRF microscopy in lung epithelial A549 cells

(2011) Irina Akopova et al.   Purinergic Signalling

Calcium Control of Neurotransmitter Release

(2011) T. C. Sudhof   Cold Spring Harbor Perspectives in Biology

Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse

(2010) Li Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of Egr-1 Expression in Astrocytes by HIV-1 Tat: New Insights into Astrocyte-Mediated Tat Neurotoxicity

(2010) Yan Fan et al.   Journal of Neuroimmune Pharmacology

HIV-associated brain dysfunction in the era of HAART: Reasons for hope, but continued concern

(2009) R. A. Cohen et al.   NEUROLOGY

HIV-1 Tat Co-Operates with IFN-γ and TNF-α to Increase CXCL10 in Human Astrocytes

(2009) Rachel Williams et al.   PLoS One

Morphine and HIV-Tat increase microglial-free radical production and oxidative stress: possible role in cytokine regulation

(2008) Jadwiga Turchan-Cholewo et al.   JOURNAL OF NEUROCHEMISTRY