High-fat diet modifies expression of hepatic cellular senescence gene p16(INK4a) through chromatin modifications in adult male rats

Genome-wide hepatic DNA methylation changes in high-fat diet-induced obese mice

(2017) AhRam Yoon et al.   Nutrition Research and Practice

Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism

(2015) Rafael Deminice et al.   AMINO ACIDS

High fat diet triggers cell cycle arrest and excessive apoptosis of granulosa cells during the follicular development

(2015) Yanqing Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine

(2015) Marin E. Healy et al.   JOURNAL OF HEPATOLOGY

Maternal High-Fat-Diet Programs Rat Offspring Liver Fatty Acid Metabolism

(2015) Emily L. Seet et al.   LIPIDS

Effect of a high fat, high sucrose diet on the promotion of non-alcoholic fatty liver disease in male rats: the ameliorative role of three natural compounds

(2015) Sohair M. M. Ragab et al.   Lipids in Health and Disease

High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

(2015) Zhigang Liu et al.   PLoS One

High-Fat Diet-Induced Adiposity, Adipose Inflammation, Hepatic Steatosis and Hyperinsulinemia in Outbred CD-1 Mice

(2015) Mingming Gao et al.   PLoS One

Hepatic inflammation scores correlate with common carotid intima-media thickness in rats with NAFLD induced by a high-fat diet

(2014) Jing Wu et al.   BMC Veterinary Research

Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring

(2014) R. O. Benatti et al.   BRITISH JOURNAL OF NUTRITION

Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice

(2014) Takeo Toshima et al.   HEPATOLOGY

Hepatocyte senescence induced by radiation and partial hepatectomy in rat liver

(2014) Maria Paola Serra et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

(2014) Xiaobing Tan et al.   PLoS One

Gallic Acid Ameliorated Impaired Glucose and Lipid Homeostasis in High Fat Diet-Induced NAFLD Mice

(2014) Jung Chao et al.   PLoS One

Short Term Feeding of a High Fat Diet Exerts an Additive Effect on Hepatocellular Damage and Steatosis in Liver-Specific PTEN Knockout Mice

(2014) Colin T. Shearn et al.   PLoS One

Ameliorative Potential ofTamarindus indicaon High Fat Diet Induced Nonalcoholic Fatty Liver Disease in Rats

(2014) Suja Rani Sasidharan et al.   TheScientificWorldJOURNAL

Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts

(2014) Wulamujiang Aini et al.   TRANSPLANT IMMUNOLOGY

High fat diet feeding results in gender specific steatohepatitis and inflammasome activation

(2014) Michal Ganz   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of a high-fat diet in development of colonic adenoma in an animal model

(2014) Qing-Chao Zhu   WORLD JOURNAL OF GASTROENTEROLOGY

Differential effects of low-fat and high-fat diets on fed-state hepatic triacylglycerol secretion, hepatic fatty acid profiles, and DGAT-1 protein expression in obese-prone Sprague–Dawley rats

(2013) Timothy D. Heden et al.   Applied Physiology Nutrition and Metabolism

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

(2013) Takuji Ishimoto et al.   HEPATOLOGY

Lessons from Mouse Models of High-Fat Diet-Induced NAFLD

(2013) Akinobu Nakamura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Molecular Balancing Act of p16 INK4a in Cancer and Aging

(2013) Kyle M. LaPak et al.   MOLECULAR CANCER RESEARCH

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Transcriptional regulation by Polycomb group proteins

(2013) Luciano Di Croce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis

(2012) Claudia Capparelli et al.   CELL CYCLE

Assessing Cell and Organ Senescence Biomarkers

(2012) Bruno Bernardes de Jesus et al.   CIRCULATION RESEARCH

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Promoter and histone methylation and p16INK4A gene expression in colon cancer

(2012) EBRU ESIN YORUKER et al.   Experimental and Therapeutic Medicine

Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model

(2011) Xiyuan Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Expression of p16INK4a prevents cancer and promotes aging in lymphocytes

(2011) Y. Liu et al.   BLOOD

Tumor Suppressor and Aging Biomarker p16INK4aInduces Cellular Senescence without the Associated Inflammatory Secretory Phenotype

(2011) Jean-Philippe Coppé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Offspring of Mothers Fed a High Fat Diet Display Hepatic Cell Cycle Inhibition and Associated Changes in Gene Expression and DNA Methylation

(2011) Kevin J. Dudley et al.   PLoS One

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation

(2011) Benoit Guillemette et al.   PLoS Genetics

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

(2010) François R. Jornayvaz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Histone H3 Lysine 4 di-methylation: A novel mark for transcriptional fidelity?

(2010) Marina Pinskaya et al.   Epigenetics

Adiponectin Modulates C-Jun N-Terminal Kinase and Mammalian Target of Rapamycin and Inhibits Hepatocellular Carcinoma

(2010) Neeraj K. Saxena et al.   GASTROENTEROLOGY

You deserve what you eat: lessons learned from the study of the melanin-concentrating hormone (MCH)-deficient mice

(2010) Yan Wang et al.   GUT

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

(2010) Irina A. Kirpich et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Predictive chromatin signatures in the mammalian genome

(2009) G. C. Hon et al.   HUMAN MOLECULAR GENETICS

Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf

(2008) R. A.J. Signer et al.   GENES & DEVELOPMENT

High-fat diet: A trigger of non-alcoholic steatohepatitis? Preliminary findings in obese subjects

(2008) Lisis Vilar et al.   NUTRITION