Article
Thermodynamics
Sholeh Hamzehzadeh, Malihe Fardshirayeh
Summary: This study evaluated the extractive potential of various aqueous biphasic systems for biomolecules, showing that the salting-out strength of salts, PEG molecular weight, and ABS composition affect the partition coefficients of biomolecules.
FLUID PHASE EQUILIBRIA
(2021)
Article
Thermodynamics
Mafalda R. Almeida, Ana F. C. S. Rufino, Diana C. Belchior, Pedro J. Carvalho, Mara G. Freire
Summary: This study aims to characterize aqueous biphasic systems composed of cholinium carboxylate ILs, K3PO4, and water. The experimental results show that ILs can effectively separate high-value compounds, and the alkyl chain length of IL anions exhibits an odd-even effect on the partitioning of alkaloids.
FLUID PHASE EQUILIBRIA
(2022)
Article
Engineering, Chemical
Jiaming Mao, Yanbin Yun, Meng Li, Wenli Liu, Chang Li, Liming Hu, Jia Liu, Lihua Wang, Chunli Li
Summary: A new sustainable dual-functionalized amino ionic liquid biphasic solvent was proposed for CO2 capture. The solvent exhibited a CO2 absorption loading of 1.95 mol CO2 center dot L-1 solvent and a CO2-rich phase with a loading of 4.65 mol CO2 center dot L-1 solvent. The solvent could be regenerated by 92.3% in 10 minutes at 373 K, and its regeneration efficiency remained at 83% after 10 cycles. The energy consumption for CO2 desorption was significantly reduced compared to ethanolamine. This solvent provides a sustainable strategy for advancing carbon capture technologies.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Chemical
Yuqiu Chen, Xiaodong Liang, John M. Woodley, Georgios M. Kontogeorgis
Summary: In this study, the phase equilibria behavior of IL-ABS was predicted using an extended IL database, a popular three-parameter model, and an artificial neural network. The proposed nonlinear ANN-GC model showed promising results in predicting phase equilibria behavior of IL-ABS. Issues governing the phase equilibria behavior of IL-ABS were also discussed for guidance in the design of IL-ABS.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Engineering, Chemical
Nosaibah Ebrahimi, Rahmat Sadeghi
Summary: This study comprehensively investigated the solute partitioning behavior in biocompatible carbohydrate-polymer aqueous biphasic systems, revealing different partitioning patterns for various biomolecules. The results showed that the log K values of all target biomolecules linearly increased with decreasing water content ratio, affecting the selectivity index. Additionally, the partitioning behavior of curcumin in carbohydrate-propanol ABSs was explored, indicating that carbohydrate-PPG ABSs exhibited higher selectivity for the alkaloids studied.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Review
Chemistry, Physical
Emmanuel A. Oke, Sushma P. Ijardar
Summary: This paper discusses the advantages of using aqueous biphasic systems composed of ionic liquids in separation and purification technology, featuring quick phase separation and high efficiency.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Nicolas Dubouis, Arthur France-Lanord, Amandine Brige, Mathieu Salanne, Alexis Grimaud
Summary: Aqueous biphasic systems (ABS) can form when mixing water with two compounds with different anions, and their formation is influenced by anion size mismatch; through a combination of experimental techniques and molecular simulations, researchers found that the size and shape of anions play a significant role in the formation of ABS, providing guidelines for potential future applications.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Physical
Yanan Zhang, Fei Lu, Yang Yu, Long Su, Yanan Gao, Liqiang Zheng, Xinpei Gao
Summary: Ionic liquid/water mixtures with tunable lower critical solution temperature behavior have significant implications for liquid-liquid phase separation and purification. By adding different types of amphiphiles, the phase separation temperature of the ionic liquid solution can be regulated. Zwitterionic additives increase the phase separation temperature, while anionic additives decrease it. The amphiphile-regulated system can selectively separate different types of amino acids.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Engineering, Chemical
Petr A. Korchak, Evgenia A. Safonova, Alexey Victorov
Summary: This study systematically investigates experimental data and predictive capabilities of a family of aqueous biphasic systems. Improvements in the model are suggested for better performance. Results show that different chemical compositions affect the partitioning coefficients of L-tryptophan, indicating high potential for the extraction of biocomponents.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Chemistry, Physical
Petr A. Korchak, Evgenia A. Safonova, Alexey I. Victorov
Summary: This study obtained experimental data on the partitioning of amino acid ionic liquids in aqueous mixtures, showing that they have higher partition coefficients and specificity compared to halide ionic liquids. Hydrogen bonding is likely to play a major role in the partitioning of the solute. These amino acid ionic liquids have high potential for the extraction of small biomolecules.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Applied
Mateusz Marchel, Isabel M. Marrucho
Summary: This review summarizes and discusses the fundamental features, advantages, and disadvantages of aqueous biphasic systems (ABS) extraction as a separation and purification technology for biomolecules. The focus of the review is on quaternary ABS and their potential applications and challenges in the downstream processing of biomolecules.
SEPARATION AND PURIFICATION REVIEWS
(2023)
Article
Engineering, Chemical
Yiota-Victoria Phakoukaki, Paul O'Shaughnessy, Panagiota Angeli
Summary: Ionic liquid based aqueous biphasic systems (IL-ABS) were formed by adding a hydrophilic ionic liquid (C4mimCl) and a kosmotropic salt (K3PO4) to water. Flow patterns in capillary channels were investigated for the first time, using three different internal diameters and weight concentrations of the IL and salt. The main flow patterns observed were plug, dispersed, and parallel flow, which were influenced by both channel diameter and weight concentrations. A generalized flow pattern map was plotted based on capillary and Reynolds numbers, showing the collapse of plug flow boundaries.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Ana F. C. S. Rufino, Mafalda R. Almeida, Mukesh Sharma, Joao A. P. Coutinho, Mara G. Freire
Summary: With a novel ionic-liquid-based aqueous biphasic system, efficient extraction and separation of bovine serum albumin (BSA) from bovine serum was achieved, with a recovery yield of 85.6% and purity of 61.2% under optimal conditions. The system shows potential as a platform for purifying BSA from serum samples and can be applied to other valuable proteins.
APPLIED SCIENCES-BASEL
(2022)
Article
Thermodynamics
Zhiyong Su, Xin Guo, Siqi Jiang, Jisheng Li, Yangyang Xin, Shuai Zhang, Yufeng Hu, Zhichang Liu
Summary: This study focuses on a new aqueous biphasic system (ABS) composed of hydrophilic ionic liquids, salts, and water. The liquid-liquid equilibrium (LLE) data of the ABS were determined experimentally, and mathematical equations were used to fit the binodal curves. The effects of the anions structure on the phase equilibrium were investigated, and the results showed that the recovery efficiency of the ABS was related to the hydration energy of the anions and the phase ratio. The study suggests that the proposed method is an effective way to recycle [Mmim][DMP] from aqueous solutions.
JOURNAL OF CHEMICAL AND ENGINEERING DATA
(2022)
Article
Chemistry, Multidisciplinary
Ines S. Cardoso, Filipe H. B. Sosa, Armando J. D. Silvestre, Anthony Robert, Mara G. Freire, Aminou Mohamadou
Summary: The use of biobased and bioactive compounds has led to the development of sustainable extraction and purification processes using ionic liquids. In this study, six novel analogues of glycine-betaine ILs (AGB-ILs) were investigated for their potential use in IL-based ABS. The synthesized ILs showed relatively low ecotoxicity and good thermal stability. The extraction efficiency of furfural using AGB-ILs-based ABS was found to be up to 98%, suggesting the potential of these novel ABS for separation of bioactive compounds.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Engineering, Chemical
Cunshan Zhou, Zhe Cai, Xule Wang, Yabin Feng, Xin Xu, Abu ElGasim A. Yagoub, Hafida Wahia, Haile Ma, Yanhui Sun
Summary: This study evaluated the impact of simultaneous tri-frequency ultrasound combined vacuum assisted ethanol pretreatment on the drying process, qualities, and microbial safety of scallion stalk slices. The Ethanol + USVC pretreatment significantly reduced drying time, retained flavor, and exhibited antibacterial effects, resulting in slices with moderate rehydration ratio and surface color change.
Review
Food Science & Technology
Cunshan Zhou, Clinton E. Okonkwo, Adejumoke A. Inyinbor, Abu ElGasim A. Yagoub, Abiola F. Olaniran
Summary: Traditional food processing techniques are no longer sufficient to meet the increasing demand for high quality food. Infrared (IR) and ultrasound (US) technologies have emerged as promising alternatives to improve processing efficiency, nutrient retention, product quality, and shelf life.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Huiling Chen, Baoguo Xu, Cunshan Zhou, Abu El-Gasim A. Yagoub, Zhe Cai, Xiaojie Yu
Summary: Developing various zein distribution mechanisms for encapsulating hydrophobic nutraceuticals is a current focus in the food industry. This study demonstrated that the multi-frequency ultrasound-assisted dialysis method can produce stable nanoparticles with improved storage stability, featuring a synergistic effect between ultrasound and sodium caseinate. The findings suggest that ultrasound-assisted dialysis is effective in encapsulating hydrophobic bioactive compounds and improving their controlled release and sustained-release properties.
FOOD HYDROCOLLOIDS
(2022)
Article
Chemistry, Applied
Qiaolan Sun, Xiaoqian Song, Mujumdar Arun, Long Zhang, Xiaojie Yu, Cunshan Zhou, Yuxin Tang, Abu ElGasim Ahmed Yagoub
Summary: This study investigates the effects of different drying methods on the structure and functional properties of sweet potato starch. The results show that BCIRB-BCIRD method better retains the structure and functional properties of the starch compared to WB-BCIRD method.
FOOD HYDROCOLLOIDS
(2022)
Article
Nutrition & Dietetics
Nadiah S. Alzahrani, Ghedeir M. Alshammari, Afaf El-Ansary, Abu ElGasim A. Yagoub, Musarat Amina, Ali Saleh, Mohammed Abdo Yahya
Summary: This study found that whole pearl millet grain powder and its ethanol extract have anti-hyperlipidemic, hypoglycemic, hepatoprotective, and anti-inflammatory effects. The study used obese rats fed a high-fat diet and divided them into different treatment groups, administering varying doses of MPG powder or MPGethaolE, and observed changes in different indicators.
Article
Food Science & Technology
Lei Zhang, Yang Hu, Xue Wang, Ao Zhang, Xianli Gao, Abu El-Gasim A. Yagoub, Haile Ma, Cunshan Zhou
Summary: In this study, the micromorphology and microstructure of nano-ZnO synthesized by the ultrasonic method were compared with that by the mechanical stirring method. The on-line monitoring of different ultrasonic fields during the synthesis process of nano-ZnO was studied, and the physical mechanism of ultrasound-assisted synthesis of nano-ZnO was revealed.
Article
Chemistry, Multidisciplinary
Laila Naif Al-Harbi, Ghedier M. Al-Shammari, Pandurangan Subash-Babu, Mohammed A. Mohammed, Roaa Ahmed Alkreadees, Abu ElGasim Ahmed Yagoub
Summary: This study synthesized iron oxide nanoparticles loaded with quinine and alkaloids-rich Cinchona officinalis stem bark extract, and investigated their cytotoxicity and apoptosis mechanisms in MCF-7 breast cancer cells. The results showed that CO-NPs reduced MCF-7 cell viability, induced nuclear condensation, chromatin damage, and decreased mitochondrial membrane potential. Furthermore, gene expression analysis revealed upregulation of tumor suppressors and apoptotic stimulators, as well as increased inflammatory traits in cancer cells treated with CO-NPs.
Article
Agronomy
Eman A. Mohammed, Ismat G. Abdalla, Mohammed A. Alfawaz, Mohammed A. Mohammed, Salah A. Al Maiman, Magdi A. Osman, Abu ElGasim A. Yagoub, Amro B. Hassan
Summary: This study investigated the total phenolics, total flavonoids, and antioxidant activity of the aerial parts of onion, white radish, red radish, carrot, and beet. The results showed that these vegetables have high antioxidant properties, with root vegetables exhibiting particularly strong antioxidant capacity.
Article
Chemistry, Multidisciplinary
Abu ElGasim A. Yagoub, Ghedeir M. Al-Shammari, Laila Naif Al-Harbi, Pandurangan Subash-Babu, Rasha Elsayim, Mohammed A. Mohammed, Mohammed Abdo Yahya, Sndos Z. A. Fattiny
Summary: In this study, in vitro biosynthesized ZnO nanoparticles were used to examine their antimicrobial efficacy against various microorganisms. The formation and stability of the nanoparticles were confirmed through multiple analytical methods. The results showed that the nanoparticles outperformed their water counterparts in terms of antimicrobial activity, with different inhibitory effects on different microorganisms. Additionally, SEM images revealed cellular alterations in response to the nanoparticle treatments. Overall, the biosynthesized LP-ZnO NPs demonstrated promising antibacterial properties and could contribute to the development of new antimicrobial drugs in the future.
APPLIED SCIENCES-BASEL
(2022)
Article
Multidisciplinary Sciences
Yuanfan Yang, Cunshan Zhou, Haile Ma, Yating Dong, Jiayu Fu, Xiaoyan Lai, Abu El-Gasim A. Yagoub, Wenjun Peng, Hui Ni
Summary: This study evaluated the potential of Camellia pollen extracts as an antioxidant and lipase activity inhibitor, and found that the extracts exhibited dual benefits in terms of lipase inhibition and antioxidant activity.
Review
Food Science & Technology
Yuqing Wang, Long Zhang, Xiaojie Yu, Cunshan Zhou, Abu ElGasim Ahmed Yagoub, Dajing Li
Summary: The preservation and processing of fruits and vegetables require high-quality raw materials, and blanching in hot water is a common pre-treatment method. Traditional blanching has drawbacks of high water and energy usage, as well as poor product quality. However, the new technology of catalytic infrared blanching offers homogeneous heating, rapid heat transmission, and high-quality products with low energy consumption and environmental preservation. Recent research has focused on combining infrared technology and catalytic infrared processing to enhance flexibility and durability.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Agricultural Engineering
Aiping Lu, Xiaojie Yu, Qinghua Ji, Li Chen, Abu El-Gasim Yagoub, Fakayode Olugbenga, Cunshan Zhou
Summary: In this study, lignin-containing cellulose nanocrystals (LCNC) were prepared from peanut shells using ultrasonic-assisted deep eutectic solvents (DES). The DES pretreatment effectively increased the cellulose content of the peanut shells, while removing lignin and hemicellulose. The resulting LCNC exhibited good thermal stability and potential for further applications.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Nutrition & Dietetics
Alaa Hasanain Felemban, Ghedeir M. Alshammari, Abu ElGasim Ahmed Yagoub, Laila Naif Al-Harbi, Maha H. Alhussain, Mohammed Abdo Yahya
Summary: This study revealed that royal jelly (RJ) protects against high-fat-diet (HFD)-mediated non-alcoholic liver disease (NAFLD) in rats. RJ treatment reduced weight gain, increased fat pads, and improved metabolic abnormalities in the HFD-fed rats. It also modulated the levels of liver enzymes, inflammatory cytokines, and adipokines, as well as the expression of genes involved in lipid metabolism.
Article
Biotechnology & Applied Microbiology
Khadijah M. Altamimy, Ghedeir M. Alshammari, Abu ElGasim A. Yagoub, Norah A. Albekairi, Samiyah Alshehri, Ali Saleh, Mohammed Abdo Yahya
Summary: This study demonstrates the therapeutic potential of fermented goat milk in treating non-alcoholic fatty liver disease induced by a high-fat diet. The fermented goat milk reduces weight gain, improves glucose and insulin homeostasis, and protects liver function in rats. Furthermore, it exhibits antioxidant properties and reduces the levels of triglycerides, cholesterol, and inflammatory markers in the liver and blood.
FERMENTATION-BASEL
(2022)
Article
Biotechnology & Applied Microbiology
Layla K. Mohamed, Mashair A. Sulieman, Abu ElGasim A. Yagoub, Mohammed A. Mohammed, Haya F. Alhuthayli, Isam A. Mohamed Ahmed, Salah A. Almaiman, Mohammed A. Alfawaz, Magdi A. Osman, Amro B. Hassan
Summary: The study found that traditional Sudanese asida prepared from irradiated sorghum flour exhibited high antioxidant activity in both sorghum cultivars, although it resulted in a significant reduction in phytochemical content.
FERMENTATION-BASEL
(2022)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
