Article
Polymer Science
Paola Franco, Iolanda De Marco
Summary: In this study, rutin-beta-cyclodextrin inclusion complexes were prepared using Supercritical AntiSolvent (SAS) precipitation. The well-defined composite microparticles showed significantly improved dissolution rate compared to unprocessed rutin, leading to a reduction in polymer amount in the SAS composite formulations.
Article
Chemistry, Multidisciplinary
Iolanda De Marco
Summary: This study conducted a life cycle assessment of the environmental impacts of producing PVP/PDS powders by supercritical antisolvent precipitation. The analysis identified the stabilizing of operating conditions, injection step, and washing step as the most impactful processes on the environment. An improved scenario was proposed to reduce the global impact by 85.8%.
JOURNAL OF CO2 UTILIZATION
(2022)
Article
Chemistry, Physical
Camila Dal Magro, Aline E. dos Santos, Marcela M. Ribas, Gean P. S. Aguiar, Carolin R. B. Volfe, Maria L. L. C. Lopes, Anna M. Siebel, Liz G. Muller, Adailton J. Bortoluzzi, Marcelo Lanza, J. Vladimir Oliveira
Summary: The study successfully synthesized a curcumin-resveratrol cocrystal using the Cocrystallization with Supercritical Solvent (CSS) technique, improving solubility and dissolution rate of the components while enhancing antioxidant activity. Behavioral tests in mice showed increased antinociceptive/anti-inflammatory potency, indicating potential pharmaceutical application.
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Article
Chemistry, Physical
Paula de Freitas Rosa Remiro, Paulo de Tarso Vieira Rosa, Angela Maria Moraes
Summary: This study aimed to promote the micronization of imiquimod using the SAS process, finding that increasing pressure tends to increase particle size, concentration leads to an increase in size, and temperature results in a reduction in size. The combination of process variables affects particle size and yield, enhancing data reproducibility.
JOURNAL OF SUPERCRITICAL FLUIDS
(2022)
Article
Thermodynamics
Yuanlu Li, Gongming Xin, Baoqiang Yuan, Shuangxing Zhang, Wenjing Du
Summary: This study experimentally investigated the heat transfer characteristics of natural circulation of supercritical CO2, revealing two heat transfer modes: normal heat transfer and heat transfer deterioration. By introducing new dimensionless parameters, a deterioration criterion and a heat transfer correlation suitable for natural circulation of supercritical CO2 were developed, which are significant for engineering applications.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2023)
Article
Thermodynamics
Qiao Luo, Yuan Zhou, Yanping Huang, Jiajian Huang, Wei Hu, Yuan Yuan, Longchang Tang
Summary: To solve the energy crisis, many countries have been exploring alternative energy sources and more efficient power cycle systems. One of the systems that has attracted widespread attention is the flexible operation supercritical carbon dioxide (S-CO2) power cycle system with a compact structure. However, the problem of flow instability in the natural circulation parallel channel system needs to be addressed. This paper presents experimental results and a theoretical model to study the flow characteristics of S-CO2 natural circulation with parallel channels, discussing different types of flow instability phenomena and their impacts on the system.
Article
Chemistry, Multidisciplinary
Jeovan A. Araujo, Muhammad Azeem, Chaitra Venkatesh, Marija Mojicevic, Margaret Brennan Fournet, Olivia A. Attallah
Summary: This study proposes an adaptable all green fabrication process for naturally colored bioplastic films with improved color stability, which aligns with the United Nations Sustainable Development Goals 9 and 12 by promoting the use of revalorized biomass and the elimination of hazardous chemicals. The colored films containing the hybrid fillers demonstrate significantly improved color stability under weathering conditions, making them a sustainable alternative to synthetic colored conventional plastics that are toxic and environmentally polluting.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Food Science & Technology
Alaitz Etxabide, Paul A. Kilmartin, Juan Mate
Summary: The study found that E-100 provided color variations (yellow/brown-yellow) at pH > 9, while E-162 and E-163 were thermosensitive and showed lower color loss (30%) after 28 days of storage. E-163, especially, had a broader color response (red-purple-blue-green) over a wider pH range.
Review
Food Science & Technology
Erika N. Vega, Maria Ciudad-Mulero, Virginia Fernandez-Ruiz, Lillian Barros, Patricia Morales
Summary: In recent years, there has been a significant increase in the demand for healthier food products and products made with natural ingredients. This is due to the awareness of the impact of food on human health and the evidence of side effects caused by certain additives. Researchers have focused on obtaining colorants from natural sources that are safe for consumption and exhibit biological activity. This review summarizes research on various natural sources of colorant compounds published in the past 15 years, including their extraction, identification, efforts to improve stability, and incorporation into different food matrices. The review showcases the promising development of natural colorants as alternatives to artificial ones.
Article
Chemistry, Applied
Alicia Gil-Ramirez, Irene Rodriguez-Meizoso
Summary: This article discusses the advantages of supercritical fluids in the isolation of natural products, focusing on the extraction of polyphenols and carotenoids. It also highlights the lack of clear terminology and purpose in the field, while aiming to inspire further research in this area of study.
SEPARATION AND PURIFICATION REVIEWS
(2021)
Article
Chemistry, Physical
Lijuan Yang, William Z. Xu, Dicho Zomaya, Paul A. Charpentier
Summary: This study employed supercritical carbon dioxide (scCO(2)) to impregnate MMA monomer into different types of softwood, and achieved improved wood properties through in-situ polymerization in scCO(2). The results showed that impregnating PMMA into wood greatly improved its material properties, and the supercritical CO2 process provides a novel and green technique for the manufacturing of next generation construction products.
JOURNAL OF SUPERCRITICAL FLUIDS
(2022)
Article
Chemistry, Multidisciplinary
Tao Wang, Xiangyang Liu, Jimin Xu, Waheed Afzal, Maogang He
Summary: This study investigated the gasification of softwood lignin in a supercritical carbon dioxide environment using platinum nanoparticles as catalysts. The results showed that the addition of catalyst increased the amount of CO2 cracking, the production of H-2 and CO molecules, and the reaction rate.
JOURNAL OF CO2 UTILIZATION
(2022)
Article
Green & Sustainable Science & Technology
Madagonda K. Biradar, Dipal N. Parmar, Ajay Kumar Yadav
Summary: This paper focuses on the study of heat transfer and fluid flow behavior in a CO2-based naturally circulated indirect solar water heating system. By comparing it with a water-based system, the CO2-based system demonstrates higher energy efficiency and exergy efficiency.
Article
Immunology
Alessandro R. Paulazzi, Bianca O. Alves, Gabriela A. L. Zilli, Aline E. dos Santos, Fernanda Petry, Krissie D. Soares, Leticia J. Danielli, Jefferson Pedroso, Miriam A. Apel, Gean Pablo S. Aguiar, Anna M. Siebel, J. Vladimir Oliveira, Liz Girardi Muller
Summary: This study successfully produced curcumin cocrystals using the anti-solvent gas technique and evaluated their solubility and anti-inflammatory potential. The cocrystals exhibited higher solubility and stronger anti-inflammatory activity compared to pure curcumin, which could be attributed to improved bioavailability.
INFLAMMOPHARMACOLOGY
(2022)
Article
Energy & Fuels
Shoaib Memon, Runhua Feng, Muhammad Ali, Masood Ahmed Bhatti, Ausama Giwelli, Alireza Keshavarz, Quan Xie, Mohammad Sarmadivaleh
Summary: It has been found that the interaction between supercritical CO2 and shale during hydraulic fracturing can alter the petrophysical properties of the rock and result in a reduction of fracture aperture, thereby decreasing the post-fracturing productivity of the rock.
Review
Chemistry, Applied
D. Cantero, R. Jara, A. Navarrete, L. Pelaz, J. Queiroz, S. Rodriguez-Rojo, M. J. Cocero
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 10
(2019)
Article
Agronomy
Seyed Mohammad Ahsaei, Soraya Rodriguez-Rojo, Marta Salgado, Maria Jose Cocero, Khalil Talebi-Jahromi, Ghassem Amoabediny
Article
Engineering, Chemical
Agostinho M. R. C. Alexandre, Ana A. Matias, Maria Rosario Bronze, Maria Jose Cocero, Rafael Mato
Article
Chemistry, Physical
Ryuto Inoue, Jonas Karl Christopher N. Agutaya, Armando T. Quitain, Mitsuru Sasaki, Maria Jose Cocero, Tetsuya Kida
Summary: The supercritical CO2-subcritical H2O system can serve as a reaction solvent for organic synthesis, promoting the conversion of organic compounds due to enhanced formation of carbonic acid and ionization of water under elevated pressures and temperatures. The biphasic nature of the system allows for extraction of less polar products from aqueous solutions. Experimental results showed higher yields and selectivity in converting glucose to HMF in this system, with potential mechanisms determined through quantum calculations.
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Article
Chemistry, Physical
Rafaella T. Buratto, Maira I. Chinchilla, Maria Jose Cocero, Angel Martin
Summary: Acai, a black-purple berry found in the Amazon Rainforest, is a rich source of polyphenols and flavonoids with antioxidant and anti-inflammatory properties. The precipitation and encapsulation of Acai extracts using the SAS process can protect active compounds from early degradation. Ethanol and PVP were found to be effective in reducing particle size and increasing total polyphenols content in the extracts.
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Article
Chemistry, Physical
Gerardo Joaquin Tita, Alexander Navarrete, Angel Martin, Maria Jose Cocero
Summary: This study investigated the supercritical fluid extraction of valuable compounds such as solanesol and nicotine from tobacco scrap, as well as the fractionation of these compounds by liquid-liquid extraction. The results show that different extraction conditions are needed for optimizing solanesol yield and selectivity compared to nicotine extraction, with the best results obtained when extraction was controlled by solubility parameters. This research provides guidance for the valorization of residues from the tobacco industry.
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Editorial Material
Chemistry, Physical
Julian Martinez, Maria Jose Cocero, Sandra Regina Salvador Ferreira, Selva Pereda
JOURNAL OF SUPERCRITICAL FLUIDS
(2021)
Article
Chemistry, Physical
Ana B. Paninho, Ana N. Mustapa, Kamran T. Mahmudov, Armando J. L. Pombeiro, M. Fatima C. Guedes da Silva, Maria D. Bermejo, Angel Martin, Maria J. Cocero, Ana V. M. Nunes
Summary: By incorporating the ionic liquid [Aliquat][Cl] into alginate and silica aerogel matrices, and applying it as a catalyst in the cycloaddition reaction between CO2 and a bio-based epoxide, it was found that the efficiency of the alginate aerogel system surpassed that of the silica aerogel system. Multiple characterization techniques were used to analyze the final materials, and several catalytic tests were conducted under high-pressure conditions.
Article
Biochemistry & Molecular Biology
Ana Alvarez, Sara Terreros, Maria J. Cocero, Rafael B. Mato
Summary: The study examined the potential of saffron flowers as a source of polyphenols and anthocyanins for extraction of bioactive compounds and production of cyanic colorant. Microwave pretreatment was proposed as an intensification step before conventional solid-liquid extraction process, effectively increasing yield and improving product quality.
Article
Green & Sustainable Science & Technology
Tijana Adamovic, Dmitry Tarasov, Emre Demirkaya, Mikhail Balakshin, Maria Jose Cocero
Summary: This study focuses on the hydrolysis of defatted grape in supercritical water, with attention to sugars recovery in the liquid phase and characterization of the solid phase enriched in polyaromatics. Carbohydrate hydrolysis led to the recovery of 56% of carbohydrates in the liquid phase, with the high content of lignin in biomass acting as a mass transfer limitation. The complex mixture of lipophilic extractives, flavonoids, and lignin extracted from the solid phase showed subtle changes in main lignin moieties, which is crucial for further valorization.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Agricultural Engineering
Eduardo Perez, Nerea Abad-Fernandez, Tainise Lourencon, Mikhail Balakshin, Herbert Sixta, Maria Jose Cocero
Summary: Different lignins from various sources were depolymerized in alkaline supercritical water, resulting in high value-added compounds with low-molecular-weight. The properties and yields of the products depended on the starting material and processing method.
BIOMASS & BIOENERGY
(2022)
Article
Chemistry, Multidisciplinary
Elaine G. Mission, Maria Jose Cocero
Summary: This study presents a novel and scalable approach for accessing suberin from cork by proposing ultrafast supercritical hydrolysis. The study highlights the importance of obtaining high-quality and highly functionalized biopolymers as a source of new building blocks. The research contributes to the development of a sustainable process for extracting valuable molecules from cork.
Article
Chemistry, Physical
Nerea Abad-Fernandez, Eduardo Perez, Angel Martin, Maria J. Cocero
JOURNAL OF SUPERCRITICAL FLUIDS
(2020)
Article
Chemistry, Multidisciplinary
Nerea Abad-Fernandez, Eduardo Perez, Maria Jose Coceroe
Article
Energy & Fuels
Rafaella T. Buratto, Maria Jose Cocero, Angel Martin
Summary: The study characterizes residual fractions of acai processing and evaluates their potential as biomass and phytochemical sources. Microwave pre-treatments increase polyphenol contents and antioxidant activities in extracts, making them valuable for the cosmetic or food industry.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.