Epigenetic modifications-insight into oligodendrocyte lineage progression, regeneration, and disease

Evidence for the implication of the histone code in building the genome structure

(2018) Kirti Prakash et al.   BIOSYSTEMS

A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration

(2018) Xuelian He et al.   NATURE MEDICINE

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities

(2017) Benjamin J. Manning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA-binding Protein Quaking StabilizesSirt2mRNA during Oligodendroglial Differentiation

(2017) Merlin P. Thangaraj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury

(2017) Toru Doi et al.   JOURNAL OF NEUROSCIENCE

lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1 /Suz12 Complex in the CNS

(2017) Danyang He et al.   NEURON

Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration

(2017) Valérie Brügger et al.   Nature Communications

A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2

(2017) Jing Zhou et al.   Cell Reports

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders

(2017) Godwin Sokpor et al.   Frontiers in Molecular Neuroscience

Epigenetic response to environmental stress: Assembly of BRG1–G9a/GLP–DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

(2016) Pei Han et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein aggregate formation in oligodendrocytes: tau and the cytoskeleton at the intersection of neuroprotection and neurodegeneration

(2016) Christiane Richter-Landsberg   BIOLOGICAL CHEMISTRY

Restoration of Visual Function by Enhancing Conduction in Regenerated Axons

(2016) Fengfeng Bei et al.   CELL

ATP-dependent chromatin remodeling during mammalian development

(2016) Swetansu K. Hota et al.   DEVELOPMENT

Brg1 directly regulates Olig2 transcription and is required for oligodendrocyte progenitor cell specification

(2016) Steven Matsumoto et al.   DEVELOPMENTAL BIOLOGY

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch

(2016) Liguo Zhang et al.   DEVELOPMENTAL CELL

CHD8 intragenic deletion associated with autism spectrum disorder

(2016) Elliot S. Stolerman et al.   European Journal of Medical Genetics

Histone deacetylase inhibition is cytotoxic to oligodendrocyte precursor cells in vitro and in vivo

(2016) Toros A. Dincman et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

(2016) Yuta Katayama et al.   NATURE

Targeting EZH2 in cancer

(2016) Kimberly H Kim et al.   NATURE MEDICINE

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination

(2016) Danyang He et al.   NATURE NEUROSCIENCE

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

A proton spectroscopy study of white matter in children with autism

(2016) Antonio Y. Hardan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

(2016) Chenglu Xiao et al.   Nature Communications

Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury

(2016) Beata Jablonska et al.   Nature Communications

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage

(2016) Sarah Moyon et al.   Cell Reports

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium

(2015) S. Chen et al.   DEVELOPMENT

How to make an oligodendrocyte

(2015) S. A. Goldman et al.   DEVELOPMENT

Brg1-Dependent Chromatin Remodelling Is Not Essentially Required during Oligodendroglial Differentiation

(2015) M. Bischof et al.   JOURNAL OF NEUROSCIENCE

Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development

(2015) J. Dai et al.   JOURNAL OF NEUROSCIENCE

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

(2015) Madhusoodanan Mottamal et al.   MOLECULES

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

(2015) Guohua Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

(2015) Ben Emery et al.   Cold Spring Harbor Perspectives in Biology

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

(2015) Justin Cotney et al.   Nature Communications

Histone Deacetylases Positively Regulate Transcription through the Elongation Machinery

(2015) Celeste B. Greer et al.   Cell Reports

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

(2014) Raphael Bernier et al.   CELL

Nonequivalent Response to Bromodomain-Targeting BET Inhibitors in Oligodendrocyte Cell Fate Decision

(2014) Cheng-Ming Chiang   CHEMISTRY & BIOLOGY

Selective Chemical Modulation of Gene Transcription Favors Oligodendrocyte Lineage Progression

(2014) Mar Gacias et al.   CHEMISTRY & BIOLOGY

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

(2014) Monika Noack et al.   GLIA

Effects of histone deacetylase inhibition on the survival, proliferation and migration of Schwann cells, as well as on the expression of neurotrophic factors and genes associated with myelination

(2014) YAZHOU WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Histone deacetylase expression in white matter oligodendrocytes after stroke

(2014) Haifa Kassis et al.   NEUROCHEMISTRY INTERNATIONAL

White-matter relaxation time and myelin water fraction differences in young adults with autism

(2014) S. C. L. Deoni et al.   PSYCHOLOGICAL MEDICINE

Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition

(2014) R. Marmorstein et al.   Cold Spring Harbor Perspectives in Biology

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

Neural Stem Cell Differentiation Is Dictated by Distinct Actions of Nuclear Receptor Corepressors and Histone Deacetylases

(2014) Gonçalo Castelo-Branco et al.   Stem Cell Reports

Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation

(2013) Yang Yu et al.   CELL

Intrinsic and extrinsic control of oligodendrocyte development

(2013) J Bradley Zuchero et al.   CURRENT OPINION IN NEUROBIOLOGY

NF- B Forms a Complex with the Chromatin Remodeler BRG1 to Regulate Schwann Cell Differentiation

(2013) A. S. Limpert et al.   JOURNAL OF NEUROSCIENCE

Optic neuritis

(2013) Ahmed T Toosy et al.   LANCET NEUROLOGY

Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain

(2013) Victoria A. Rafalski et al.   NATURE CELL BIOLOGY

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

(2013) Seo-Hee You et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SWI/SNF Enzymes Promote SOX10- Mediated Activation of Myelin Gene Expression

(2013) Himangi G. Marathe et al.   PLoS One

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

The ways and means that fine tune Sirt1 activity

(2013) Javier R. Revollo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chromatin-Remodeling Factor Brg1 Is Required for Schwann Cell Differentiation and Myelination

(2012) Matthias Weider et al.   DEVELOPMENTAL CELL

Copy number variation of individual cattle genomes using next-generation sequencing

(2012) D. M. Bickhart et al.   GENOME RESEARCH

Histone deacetylase activity is required for human oligodendrocyte progenitor differentiation

(2012) Gregory D. Conway et al.   GLIA

Valproic acid increases white matter repair and neurogenesis after stroke

(2012) X.S. Liu et al.   NEUROSCIENCE

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

Readers of histone modifications

(2011) Miyong Yun et al.   CELL RESEARCH

CHD7 mutations and CHARGE syndrome: the clinical implications of an expanding phenotype

(2011) J. E. H. Bergman et al.   JOURNAL OF MEDICAL GENETICS

Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions

(2011) X. Pedre et al.   JOURNAL OF NEUROSCIENCE

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

(2011) Ying Chen et al.   NATURE NEUROSCIENCE

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

(2011) Claire Jacob et al.   NATURE NEUROSCIENCE

Identification of a Gene Regulatory Network Necessary for the Initiation of Oligodendrocyte Differentiation

(2011) Victoria A. Swiss et al.   PLoS One

Sirt2 is a novel in vivo downstream target of Nkx2.2 and enhances oligodendroglial cell differentiation

(2011) S. Ji et al.   Journal of Molecular Cell Biology

Hdac1 and Hdac2 Act Redundantly to Control p63 and p53 Functions in Epidermal Progenitor Cells

(2010) Matthew LeBoeuf et al.   DEVELOPMENTAL CELL

CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome

(2010) T. Batsukh et al.   HUMAN MOLECULAR GENETICS

Oral Resveratrol Reduces Neuronal Damage in a Model of Multiple Sclerosis

(2010) Kenneth S Shindler et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Chromatin Remodeling in Development and Disease: Focus on CHD7

(2010) Donna M. Martin   PLoS Genetics

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Understanding the Words of Chromatin Regulation

(2009) Jiang I. Wu et al.   CELL

ATP-dependent chromatin remodeling in neural development

(2009) Andrew S Yoo et al.   CURRENT OPINION IN NEUROBIOLOGY

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

MRI Findings in 77 Children with Non-Syndromic Autistic Disorder

(2009) Nathalie Boddaert et al.   PLoS One

Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells

(2008) Hedi Liu et al.   GLIA

Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death

(2008) Suping Wang et al.   STROKE

SIRT2, tubulin deacetylation, and oligodendroglia differentiation

(2007) Bor Luen Tang et al.   CELL MOTILITY AND THE CYTOSKELETON