HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

(2013) Christiane Richter-Landsberg et al.   ACTA NEUROPATHOLOGICA

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

(2013) Claudia Simões-Pires et al.   Molecular Neurodegeneration

Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system

(2013) Min Jae Lee et al.   PROGRESS IN NEUROBIOLOGY

Brain expression level and activity of HDAC6 protein in neurodegenerative dementia

(2012) Saori Odagiri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Tau as a therapeutic target in neurodegenerative disease

(2012) Diana S. Himmelstein et al.   PHARMACOLOGY & THERAPEUTICS

HDAC6 at the Intersection of Neuroprotection and Neurodegeneration

(2012) Constantin d'Ydewalle et al.   TRAFFIC

Interplay between histone deacetylases and autophagy - from cancer therapy to neurodegeneration

(2011) Oliver Trüe et al.   IMMUNOLOGY AND CELL BIOLOGY

Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions

(2011) Yasuo Miki et al.   NEUROPATHOLOGY

Immunohistochemical localization of aggresomal proteins in glial cytoplasmic inclusions in multiple system atrophy

(2011) Y. Chiba et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Sirt2 is a novel in vivo downstream target of Nkx2.2 and enhances oligodendroglial cell differentiation

(2011) S. Ji et al.   Journal of Molecular Cell Biology

The acetylation of tau inhibits its function and promotes pathological tau aggregation

(2011) Todd J. Cohen et al.   Nature Communications

Papp–Lantos inclusions and the pathogenesis of multiple system atrophy: an update

(2010) Kurt A. Jellinger et al.   ACTA NEUROPATHOLOGICA

TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6

(2010) Natália Tőkési et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

(2010) Kyle V. Butler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Epigenetic regulation of oligodendrocyte identity

(2010) Jia Liu et al.   TRENDS IN NEUROSCIENCES

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6

(2009) Y. Zilberman et al.   JOURNAL OF CELL SCIENCE

Tau - an inhibitor of deacetylase HDAC6 function

(2009) Mar Perez et al.   JOURNAL OF NEUROCHEMISTRY

The role of tau in neurodegeneration

(2009) Tania F Gendron et al.   Molecular Neurodegeneration

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Multiple system atrophy: A primary oligodendrogliopathy

(2008) Gregor K. Wenning et al.   ANNALS OF NEUROLOGY

Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications

(2008) L. Chin et al.   CURRENT MEDICINAL CHEMISTRY

The expression of tubulin polymerization promoting protein TPPP/p25α is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress

(2008) Olaf Goldbaum et al.   GLIA

Histone deacetylase 6 interacts with the microtubule-associated protein tau

(2008) Huiping Ding et al.   JOURNAL OF NEUROCHEMISTRY

SIRT2, tubulin deacetylation, and oligodendroglia differentiation

(2007) Bor Luen Tang et al.   CELL MOTILITY AND THE CYTOSKELETON