- Home
- Publications
- Publication Search
- Publication Details
Title
Progranulin as a therapeutic target for dementia
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 22, Issue 7, Pages 579-585
Publisher
Informa UK Limited
Online
2018-06-12
DOI
10.1080/14728222.2018.1487951
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Progranulin: A key player in autoimmune diseases
- (2018) Jinlong Jian et al. CYTOKINE
- Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study
- (2018) David M. Cash et al. NEUROBIOLOGY OF AGING
- Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study
- (2018) Daniela Galimberti et al. NEUROBIOLOGY OF AGING
- Phenotypic Heterogeneity of the GRN Asp22fs Mutation in a Large Italian Kindred
- (2018) Anna M. Pietroboni et al. JOURNAL OF ALZHEIMERS DISEASE
- Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)
- (2017) Henri J.M.M. Mutsaerts et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Progranulin, lysosomal regulation and neurodegenerative disease
- (2017) Aimee W. Kao et al. NATURE REVIEWS NEUROSCIENCE
- Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis
- (2017) Michael E. Ward et al. Science Translational Medicine
- White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort
- (2017) Carole H. Sudre et al. NeuroImage-Clinical
- Serum Levels of Progranulin Do Not Reflect Cerebrospinal Fluid Levels in Neurodegenerative Disease
- (2016) Carlo Wilke et al. Current Alzheimer Research
- Therapy and clinical trials in frontotemporal dementia: past, present, and future
- (2016) Richard M. Tsai et al. JOURNAL OF NEUROCHEMISTRY
- Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia
- (2016) Christopher J. Holler et al. Molecular Neurodegeneration
- Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation
- (2016) Maria R. Almeida et al. NEUROBIOLOGY OF AGING
- Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists
- (2015) S. Sakura Minami et al. BIOCHEMICAL PHARMACOLOGY
- Inflammatory molecules in Frontotemporal Dementia: Cerebrospinal fluid signature of progranulin mutation carriers
- (2015) D. Galimberti et al. BRAIN BEHAVIOR AND IMMUNITY
- Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation
- (2015) Kun Huang et al. IMMUNOLOGY
- Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
- (2015) Xiaolai Zhou et al. JOURNAL OF CELL BIOLOGY
- Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
- (2015) Jonathan D Rohrer et al. LANCET NEUROLOGY
- Phenotypic Heterogeneity of Monogenic Frontotemporal Dementia
- (2015) Alberto Benussi et al. Frontiers in Aging Neuroscience
- The Evolution of the Secreted Regulatory Protein Progranulin
- (2015) Roger G. E. Palfree et al. PLoS One
- Proinflammatory Progranulin Antibodies in Inflammatory Bowel Diseases
- (2014) Lorenz Thurner et al. DIGESTIVE DISEASES AND SCIENCES
- Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity
- (2014) Qingyun Tian Frontiers in Bioscience-Landmark
- Increased Serum GP88 (Progranulin) Concentrations in Rheumatoid Arthritis
- (2014) Yasuko Yamamoto et al. INFLAMMATION
- Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
- (2014) S Sakura Minami et al. NATURE MEDICINE
- Results from a pilot study on amiodarone administration in monogenic frontotemporal dementia with granulin mutation
- (2014) A. Alberici et al. NEUROLOGICAL SCIENCES
- Progranulin protein levels are differently regulated in plasma and CSF
- (2014) A. M. Nicholson et al. NEUROLOGY
- PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner
- (2014) Fanhua Wei et al. Scientific Reports
- Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains
- (2013) Jinlong Jian et al. FEBS LETTERS
- Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency
- (2013) Wing C. Lee et al. HUMAN MOLECULAR GENETICS
- Progranulin Does Not Bind Tumor Necrosis Factor (TNF) Receptors and Is Not a Direct Regulator of TNF-Dependent Signaling or Bioactivity in Immune or Neuronal Cells
- (2013) X. Chen et al. JOURNAL OF NEUROSCIENCE
- Dissociation of Frontotemporal Dementia-Related Deficits and Neuroinflammation in Progranulin Haploinsufficient Mice
- (2013) A. J. Filiano et al. JOURNAL OF NEUROSCIENCE
- Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage
- (2012) Katherine R. Smith et al. AMERICAN JOURNAL OF HUMAN GENETICS
- PGRN is a Key Adipokine Mediating High Fat Diet-Induced Insulin Resistance and Obesity through IL-6 in Adipose Tissue
- (2012) Toshiya Matsubara et al. Cell Metabolism
- Progranulin antibodies in autoimmune diseases
- (2012) Lorenz Thurner et al. JOURNAL OF AUTOIMMUNITY
- Advances in understanding the molecular basis of frontotemporal dementia
- (2012) Rosa Rademakers et al. Nature Reviews Neurology
- Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity
- (2012) Atsushi Tanaka et al. ARTHRITIS RESEARCH & THERAPY
- A harmonized classification system for FTLD-TDP pathology
- (2011) Ian R. A. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Association of TMEM106B Gene Polymorphism With Age at Onset in Granulin Mutation Carriers and Plasma Granulin Protein Levels
- (2011) Carlos Cruchaga et al. ARCHIVES OF NEUROLOGY
- Suberoylanilide Hydroxamic Acid (Vorinostat) Up-regulates Progranulin Transcription
- (2011) Basar Cenik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rescue of Progranulin Deficiency Associated with Frontotemporal Lobar Degeneration by Alkalizing Reagents and Inhibition of Vacuolar ATPase
- (2011) A. Capell et al. JOURNAL OF NEUROSCIENCE
- Progranulin expression in brain tissue and cerebrospinal fluid levels in multiple sclerosis
- (2011) Marco Vercellino et al. Multiple Sclerosis Journal
- Optimal Plasma Progranulin Cutoff Value for Predicting Null Progranulin Mutations in Neurodegenerative Diseases: A Multicenter Italian Study
- (2011) Roberta Ghidoni et al. Neurodegenerative Diseases
- The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice
- (2011) W. Tang et al. SCIENCE
- Accelerated Lipofuscinosis and Ubiquitination in Granulin Knockout Mice Suggest a Role for Progranulin in Successful Aging
- (2010) Zeshan Ahmed et al. AMERICAN JOURNAL OF PATHOLOGY
- The Spectrum of Mutations in Progranulin
- (2010) Chang-En Yu et al. ARCHIVES OF NEUROLOGY
- TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
- (2010) N. Finch et al. NEUROLOGY
- Serum biomarker for progranulin-associated frontotemporal lobar degeneration
- (2009) Kristel Sleegers et al. ANNALS OF NEUROLOGY
- Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members
- (2009) N. Finch et al. BRAIN
- Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
- (2009) Fangfang Yin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease
- (2009) Miryam Carecchio et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study
- (2008) Isabelle Le Ber et al. BRAIN
- Serum Progranulin Concentrations May Be Associated With Macrophage Infiltration Into Omental Adipose Tissue
- (2008) B.-S. Youn et al. DIABETES
- Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration
- (2008) R. Ghidoni et al. NEUROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search