Proinflammatory Progranulin Antibodies in Inflammatory Bowel Diseases

Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice

(2013) Ryota Kawase et al.   CARDIOVASCULAR RESEARCH

Presence of Anti-proteinase 3 Antineutrophil Cytoplasmic Antibodies (Anti-PR3 ANCA) as Serologic Markers in Inflammatory Bowel Disease

(2013) Maria Teresa Arias-Loste et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains

(2013) Jinlong Jian et al.   FEBS LETTERS

Progranulin does not inhibit TNF and lymphotoxin-α signalling through TNF receptor 1

(2013) Nima Etemadi et al.   IMMUNOLOGY AND CELL BIOLOGY

The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

(2013) Yusuke Egashira et al.   Journal of Neuroinflammation

Progranulin Does Not Bind Tumor Necrosis Factor (TNF) Receptors and Is Not a Direct Regulator of TNF-Dependent Signaling or Bioactivity in Immune or Neuronal Cells

(2013) X. Chen et al.   JOURNAL OF NEUROSCIENCE

Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis

(2013) Lorenz Thurner et al.   ARTHRITIS RESEARCH & THERAPY

The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis

(2012) Sandra Garcês et al.   ANNALS OF THE RHEUMATIC DISEASES

Progranulin antibodies in autoimmune diseases

(2012) Lorenz Thurner et al.   JOURNAL OF AUTOIMMUNITY

Crohn's disease

(2012) Daniel C Baumgart et al.   LANCET

Adult-Onset Immunodeficiency in Thailand and Taiwan

(2012) Sarah K. Browne et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hyperphosphorylation of autoantigenic targets of paraproteins is due to inactivation of PP2A

(2011) K.-D. Preuss et al.   BLOOD

Towards the next generation of anti-TNF drugs

(2011) Petros P. Sfikakis et al.   CLINICAL IMMUNOLOGY

Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis

(2011) K. Leiper et al.   GUT

Structure, Function, and Mechanism of Progranulin; the Brain and Beyond

(2011) Huishi Toh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

(2011) W. Tang et al.   SCIENCE

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suppressor activity among CD4+,CD25++ T cells is discriminated by membrane-bound tumor necrosis factor α

(2008) Jun Wang et al.   ARTHRITIS AND RHEUMATISM

Ulcerative colitis following B lymphocyte depletion with rituximab in a patient with Graves' disease

(2008) D. E. Fassi et al.   GUT