Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation

Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4+ Foxp3+regulatory T cells

(2014) Ya Hu et al.   IMMUNOLOGY

Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice

(2013) Ryota Kawase et al.   CARDIOVASCULAR RESEARCH

Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice

(2013) Yun-Peng Zhao et al.   FEBS LETTERS

PGRN is a Key Adipokine Mediating High Fat Diet-Induced Insulin Resistance and Obesity through IL-6 in Adipose Tissue

(2012) Toshiya Matsubara et al.   Cell Metabolism

Significance of PC cell-derived growth factor and cyclin D1 expression in cutaneous squamous cell carcinoma

(2012) K. Huang et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

(2012) Lauren Herl Martens et al.   JOURNAL OF CLINICAL INVESTIGATION

Insights into the role of progranulin in immunity, infection, and inflammation

(2012) J. Jian et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neuroprotective effects of progranulin in ischemic mice

(2011) Jiang Tao et al.   BRAIN RESEARCH

Progranulin: A promising therapeutic target for rheumatoid arthritis

(2011) Chuan-ju Liu   FEBS LETTERS

Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells

(2011) Angelic M.G. van der Aar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peptidoglycan Recognition Protein Pglyrp2 Protects Mice from Psoriasis-like Skin Inflammation by Promoting Regulatory T Cells and Limiting Th17 Responses

(2011) S. Y. Park et al.   JOURNAL OF IMMUNOLOGY

Progranulin: A growth factor, a novel TNFR ligand and a drug target

(2011) Chuan-ju Liu et al.   PHARMACOLOGY & THERAPEUTICS

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

(2011) William R. Swindell et al.   PLoS One

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

(2011) W. Tang et al.   SCIENCE

Regulatory T cells in the skin lesions and blood of patients with systemic sclerosis and morphoea

(2010) E. Antiga et al.   BRITISH JOURNAL OF DERMATOLOGY

Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis

(2010) Jian Q. Feng et al.   FASEB JOURNAL

8-Methoxypsoralen Plus Ultraviolet A Therapy Acts via Inhibition of the IL-23/Th17 Axis and Induction of Foxp3+ Regulatory T Cells Involving CTLA4 Signaling in a Psoriasis-Like Skin Disorder

(2010) T. P. Singh et al.   JOURNAL OF IMMUNOLOGY

The granulin gene family: from cancer to dementia

(2009) Andrew Bateman et al.   BIOESSAYS

Circulating CD4+CD25brightFOXP3+ T Cells Are Up-Regulated by Biological Therapies and Correlate with the Clinical Response in Psoriasis Patients

(2009) P. Quaglino et al.   DERMATOLOGY

Profiles of Foxp3+ regulatory T cells in eczematous dermatitis, psoriasis vulgaris and mycosis fungoides

(2008) T. Fujimura et al.   BRITISH JOURNAL OF DERMATOLOGY

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

(2008) Philip Van Damme et al.   JOURNAL OF CELL BIOLOGY