Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn’s Disease

Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor

(2017) Tom Holvoet et al.   GASTROENTEROLOGY

Mechanisms, Management, and Treatment of Fibrosis in Patients With Inflammatory Bowel Diseases

(2017) Florian Rieder et al.   GASTROENTEROLOGY

Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling

(2016) Mario C. Manresa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Comparison of Adipose-Derived and Bone Marrow Mesenchymal Stromal Cells in a Murine Model of Crohn’s Disease

(2016) Minghao Xie et al.   DIGESTIVE DISEASES AND SCIENCES

Mesenchymal stromal cells and liver fibrosis: a complicated relationship

(2016) Debashis Haldar et al.   FASEB JOURNAL

Decreased Fibrogenesis After Treatment with Pirfenidone in a Newly Developed Mouse Model of Intestinal Fibrosis

(2016) Remo Meier et al.   INFLAMMATORY BOWEL DISEASES

Anti-MMP-9 Antibody

(2016) Laurence Goffin et al.   INFLAMMATORY BOWEL DISEASES

Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis

(2016) Silvia Speca et al.   INFLAMMATORY BOWEL DISEASES

European Crohn’s and Colitis Organisation Topical Review on Prediction, Diagnosis and Management of Fibrostenosing Crohn’s Disease

(2016) Florian Rieder et al.   Journal of Crohns & Colitis

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

(2016) Julián Panés et al.   LANCET

Prostaglandin E2 and Polyenylphosphatidylcholine Protect Against Intestinal Fibrosis and Regulate Myofibroblast Function

(2015) Angela C. Baird et al.   DIGESTIVE DISEASES AND SCIENCES

Allogeneic Bone Marrow–Derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients With Crohn’s Disease

(2015) Ilse Molendijk et al.   GASTROENTEROLOGY

Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine

(2015) Emanuela Sala et al.   GASTROENTEROLOGY

Use of mesenchymal stem cells to treat liver fibrosis: Current situation and future prospects

(2015) Silvia Berardis et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mesenchymal Stromal Cells in Animal Bleomycin Pulmonary Fibrosis Models: A Systematic Review

(2015) Nadim Srour et al.   Stem Cells Translational Medicine

Mesenchymal stem cells ameliorate diabetic glomerular fibrosis in vivo and in vitro by inhibiting TGF-β signalling via secretion of bone morphogenetic protein 7

(2014) Shasha Lv et al.   Diabetes & Vascular Disease Research

Mechanisms That Mediate the Development of Fibrosis in Patients With Crohnʼs Disease

(2014) Chao Li et al.   INFLAMMATORY BOWEL DISEASES

Results of the 4th Scientific Workshop of the ECCO (Group II): Markers of intestinal fibrosis in inflammatory bowel disease

(2014) Florian Rieder et al.   Journal of Crohns & Colitis

Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD

(2014) Giovanni Latella et al.   Journal of Crohns & Colitis

Mechanisms of Tissue Remodeling in Inflammatory Bowel Disease

(2013) Florian Rieder et al.   DIGESTIVE DISEASES

Anti–Tumor Necrosis Factor α Prevents Bowel Fibrosis Assessed by Messenger RNA, Histology, and Magnetization Transfer MRI in Rats With Crohnʼs Disease

(2013) Jeremy Adler et al.   INFLAMMATORY BOWEL DISEASES

IL-10 Treatment Is Associated with Prohibitin Expression in the Crohn’s Disease Intestinal Fibrosis Mouse Model

(2013) C. Yuan et al.   MEDIATORS OF INFLAMMATION

Animal models of intestinal fibrosis: new tools for the understanding of pathogenesis and therapy of human disease

(2012) Florian Rieder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Immunomodulatory properties of mesenchymal stem cells and their therapeutic applications

(2012) TacGhee Yi et al.   ARCHIVES OF PHARMACAL RESEARCH

Systemic Infusion of Bone Marrow-Derived Mesenchymal Stem Cells for Treatment of Experimental Colitis in Mice

(2012) Xiao-Wen He et al.   DIGESTIVE DISEASES AND SCIENCES

Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis

(2012) Per Anderson et al.   GUT

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Liver Fibrosis

(2012) Tingfen Li et al.   STEM CELLS AND DEVELOPMENT

Cellular and molecular mechanisms of intestinal fibrosis

(2012) Silvia Speca   WORLD JOURNAL OF GASTROENTEROLOGY

Simvastatin Attenuates Intestinal Fibrosis Independent of the Anti-Inflammatory Effect by Promoting Fibroblast/Myofibroblast Apoptosis in the Regeneration/Healing Process from TNBS-Induced Colitis

(2011) Yosuke Abe et al.   DIGESTIVE DISEASES AND SCIENCES

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

(2011) R. Ciccocioppo et al.   GUT

Role of heat shock protein 47 in intestinal fibrosis of experimental colitis

(2010) Hiroshi Kitamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study

(2010) Marjolijn Duijvestein et al.   GUT

Identification of Epithelial to Mesenchymal Transition as a Novel Source of Fibroblasts in Intestinal Fibrosis

(2010) Sarah N. Flier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow

(2009) Masoud Soleimani et al.   Nature Protocols

Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses

(2008) Manuel A. González et al.   GASTROENTEROLOGY