The dorsal column lesion model of spinal cord injury and its use in deciphering the neuron-intrinsic injury response

Identification of miRNAs involved in DRG neurite outgrowth and their putative targets

(2017) Dario Motti et al.   FEBS LETTERS

Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord

(2017) Dongsheng Wu et al.   JOURNAL OF NEUROSCIENCE

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

An Intrinsic Epigenetic Barrier for Functional Axon Regeneration

(2017) Yi-Lan Weng et al.   NEURON

The role of cAMP and its downstream targets in neurite growth in the adult nervous system

(2017) Nicholas J. Batty et al.   NEUROSCIENCE LETTERS

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury

(2016) Katalin Bartus et al.   BRAIN

Comprehensive mapping of 5-hydroxymethylcytosine epigenetic dynamics in axon regeneration

(2016) Yong-Hwee Eddie Loh et al.   Epigenetics

miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair

(2016) A. D. Gaudet et al.   JOURNAL OF NEUROSCIENCE

Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord

(2016) M. Cheah et al.   JOURNAL OF NEUROSCIENCE

The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS

(2016) Andrea Tedeschi et al.   NEURON

Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury

(2016) Miao He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensorimotor Integration by Corticospinal System

(2016) Yunuen Moreno-López et al.   Frontiers in Neuroanatomy

Evaluation of Five Tests for Sensitivity to Functional Deficits following Cervical or Thoracic Dorsal Column Transection in the Rat

(2016) Nitish D. Fagoe et al.   PLoS One

A novel and robust conditioning lesion induced by ethidium bromide

(2015) Edmund R. Hollis et al.   EXPERIMENTAL NEUROLOGY

Chondroitinase gene therapy improves upper limb function following cervical contusion injury

(2015) Nicholas D. James et al.   EXPERIMENTAL NEUROLOGY

Overexpression of ATF3 or the combination of ATF3, c-Jun, STAT3 and Smad1 promotes regeneration of the central axon branch of sensory neurons but without synergistic effects

(2015) Nitish D. Fagoe et al.   HUMAN MOLECULAR GENETICS

Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System

(2015) Mustafa M. Siddiq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement Protein C1q Modulates Neurite Outgrowth In Vitro and Spinal Cord Axon Regeneration In Vivo

(2015) S. L. Peterson et al.   JOURNAL OF NEUROSCIENCE

In vivo genome editing using Staphylococcus aureus Cas9

(2015) F. Ann Ran et al.   NATURE

A Surviving Intact Branch Stabilizes Remaining Axon Architecture after Injury as Revealed by In Vivo Imaging in the Mouse Spinal Cord

(2015) Ariana O. Lorenzana et al.   NEURON

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

(2015) Takao Omura et al.   NEURON

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Remodelling of spared proprioceptive circuit involving a small number of neurons supports functional recovery

(2015) Edmund R. Hollis et al.   Nature Communications

Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration

(2015) Mustafa M. Siddiq et al.   Frontiers in Molecular Neuroscience

In Vivo Two-Photon Imaging of Axonal Dieback, Blood Flow, and Calcium Influx with Methylprednisolone Therapy after Spinal Cord Injury

(2015) Peifu Tang et al.   Scientific Reports

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve

(2014) S A Hoyng et al.   GENE THERAPY

cAMP-responsive Element-binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-dependent Regeneration-associated Gene Expression and Neurite Growth

(2014) Thong C. Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CNS Axons Globally Increase Axonal Transport after Peripheral Conditioning

(2014) F. M. Mar et al.   JOURNAL OF NEUROSCIENCE

Entrapment via Synaptic-Like Connections between NG2 Proteoglycan+ Cells and Dystrophic Axons in the Lesion Plays a Role in Regeneration Failure after Spinal Cord Injury

(2014) Angela R. Filous et al.   JOURNAL OF NEUROSCIENCE

Effects of an Immunomodulatory Therapy and Chondroitinase After Spinal Cord Hemisection Injury

(2014) Matthew J. Grosso et al.   NEUROSURGERY

Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia

(2014) Jerry Silver et al.   Cold Spring Harbor Perspectives in Biology

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system

(2014) Radhika Puttagunta et al.   Nature Communications

Skilled Reaching and Grasping in the Rat: Lacking Effect of Corticospinal Lesion

(2014) Bror Alstermark et al.   Frontiers in Neurology

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons

(2013) N D Fagoe et al.   GENE THERAPY

Modality-Based Organization of Ascending Somatosensory Axons in the Direct Dorsal Column Pathway

(2013) J. Niu et al.   JOURNAL OF NEUROSCIENCE

A Multilevel Screening Strategy Defines a Molecular Fingerprint of Proregenerative Olfactory Ensheathing Cells and Identifies SCARB2, a Protein That Improves Regenerative Sprouting of Injured Sensory Spinal Axons

(2013) K. C. D. Roet et al.   JOURNAL OF NEUROSCIENCE

Secretory Leukocyte Protease Inhibitor Reverses Inhibition by CNS Myelin, Promotes Regeneration in the Optic Nerve, and Suppresses Expression of the Transforming Growth Factor-  Signaling Protein Smad2

(2013) S. S. Hannila et al.   JOURNAL OF NEUROSCIENCE

Contribution of Macrophages to Enhanced Regenerative Capacity of Dorsal Root Ganglia Sensory Neurons by Conditioning Injury

(2013) M. J. Kwon et al.   JOURNAL OF NEUROSCIENCE

Epigenetic Regulation of Sensory Axon Regeneration after Spinal Cord Injury

(2013) M. J. Finelli et al.   JOURNAL OF NEUROSCIENCE

Neurophysiology of gait: From the spinal cord to the frontal lobe

(2013) Kaoru Takakusaki   MOVEMENT DISORDERS

Lentiviral mediated expression of a NGF-soluble Nogo receptor 1 fusion protein promotes axonal regeneration

(2013) Yi Zhang et al.   NEUROBIOLOGY OF DISEASE

Scar-mediated inhibition and CSPG receptors in the CNS

(2012) Kartavya Sharma et al.   EXPERIMENTAL NEUROLOGY

Axonal regeneration induced by blockade of glial inhibitors coupled with activation of intrinsic neuronal growth pathways

(2012) Xingxing Wang et al.   EXPERIMENTAL NEUROLOGY

Dependence of Regenerated Sensory Axons on Continuous Neurotrophin-3 Delivery

(2012) S. Hou et al.   JOURNAL OF NEUROSCIENCE

Chronic in vivo imaging in the mouse spinal cord using an implanted chamber

(2012) Matthew J Farrar et al.   NATURE METHODS

Three-dimensional imaging of solvent-cleared organs using 3DISCO

(2012) Ali Ertürk et al.   Nature Protocols

Reinduced Wnt signaling limits regenerative potential of sensory axons in the spinal cord following conditioning lesion

(2012) E. R. Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

(2012) R. van den Brand et al.   SCIENCE

Molecular interactions underlying the specification of sensory neurons

(2012) Francois Lallemend et al.   TRENDS IN NEUROSCIENCES

gp130 cytokines are positive signals triggering changes in gene expression and axon outgrowth in peripheral neurons following injury

(2012) Richard E. Zigmond   Frontiers in Molecular Neuroscience

Phenotypic analysis of astrocytes derived from glial restricted precursors and their impact on axon regeneration

(2011) Christopher Haas et al.   EXPERIMENTAL NEUROLOGY

Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: Superiority to camp-mediated effects

(2011) Armin Blesch et al.   EXPERIMENTAL NEUROLOGY

Grafted Neural Progenitors Integrate and Restore Synaptic Connectivity across the Injured Spinal Cord

(2011) J. F. Bonner et al.   JOURNAL OF NEUROSCIENCE

Conduction Failure following Spinal Cord Injury: Functional and Anatomical Changes from Acute to Chronic Stages

(2011) N. D. James et al.   JOURNAL OF NEUROSCIENCE

The role of propriospinal interneurons in recovery from spinal cord injury

(2011) Jamie R. Flynn et al.   NEUROPHARMACOLOGY

LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data

(2011) Geert Geeven et al.   NUCLEIC ACIDS RESEARCH

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration

(2011) F. M. Bareyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons

(2011) P. Parikh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult NG2+ Cells Are Permissive to Neurite Outgrowth and Stabilize Sensory Axons during Macrophage-Induced Axonal Dieback after Spinal Cord Injury

(2010) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

A Chemical Screen Identifies Novel Compounds That Overcome Glial-Mediated Inhibition of Neuronal Regeneration

(2010) L. C. Usher et al.   JOURNAL OF NEUROSCIENCE

Genome-wide gene expression and promoter binding analysis identifies NFIL3 as a repressor of C/EBP target genes in neuronal outgrowth

(2010) Harold D. MacGillavry et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Chronically CNS-Injured Adult Sensory Neurons Gain Regenerative Competence upon a Lesion of Their Peripheral Axon

(2009) Bhavna Ylera et al.   CURRENT BIOLOGY

Preconditioning selective ventral root injury promotes plasticity of ascending sensory neurons in the injured spinal cord of adult rats - possible roles of brain-derived 
neurotrophic factor, TrkB and p75 neurotrophin receptor

(2009) Fang Li et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons

(2009) Paul N. Hoffman   EXPERIMENTAL NEUROLOGY

Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury

(2009) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

 9 Integrin Promotes Neurite Outgrowth on Tenascin-C and Enhances Sensory Axon Regeneration

(2009) M. R. Andrews et al.   JOURNAL OF NEUROSCIENCE

Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory Neurons

(2009) H. Zou et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Anatomical and Functional Outcomes following a Precise, Graded, Dorsal Laceration Spinal Cord Injury in C57BL/6 Mice

(2009) Rachel L. Hill et al.   JOURNAL OF NEUROTRAUMA

Recombinant Adeno-Associated Virus Serotype 6 (rAAV2/6)-Mediated Gene Transfer to Nociceptive Neurons through Different Routes of Delivery

(2009) Chris Towne et al.   Molecular Pain

Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury

(2009) Laura Taylor Alto et al.   NATURE NEUROSCIENCE

Combined Intrinsic and Extrinsic Neuronal Mechanisms Facilitate Bridging Axonal Regeneration One Year after Spinal Cord Injury

(2009) Ken Kadoya et al.   NEURON

Quantitative analysis by in vivo imaging of the dynamics of vascular and axonal networks in injured mouse spinal cord

(2009) C. Dray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Another Barrier to Regeneration in the CNS: Activated Macrophages Induce Extensive Retraction of Dystrophic Axons through Direct Physical Interactions

(2008) K. P. Horn et al.   JOURNAL OF NEUROSCIENCE

The differential effects of cervical and thoracic dorsal funiculus lesions in rats

(2007) S KANAGAL et al.   BEHAVIOURAL BRAIN RESEARCH

The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury

(2007) Sari S. Hannila et al.   EXPERIMENTAL NEUROLOGY

Electrical stimulation of intact peripheral sensory axons in rats promotes outgrowth of their central projections

(2007) Esther Udina et al.   EXPERIMENTAL NEUROLOGY

Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

(2007) Gregoire Courtine et al.   NATURE MEDICINE