Understanding axon guidance: are we nearly there yet?

Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation

(2017) Léa Lepelletier et al.   JOURNAL OF NEUROSCIENCE

Floor-plate-derived netrin-1 is dispensable for commissural axon guidance

(2017) Chloé Dominici et al.   NATURE

Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord

(2017) Supraja G. Varadarajan et al.   NEURON

DSCAM promotes axon fasciculation and growth in the developing optic pathway

(2017) Freyja M. Bruce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guidance of retinal axons in mammals

(2017) Eloísa Herrera et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Neuronal Subset-Specific Migration and Axonal Wiring Mechanisms in the Developing Midbrain Dopamine System

(2017) Sara Brignani et al.   Frontiers in Neuroanatomy

Sema-1a Reverse Signaling Promotes Midline Crossing in Response to Secreted Semaphorins

(2017) Melissa Hernandez-Fleming et al.   Cell Reports

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

(2017) Anaïs Bellon et al.   Cell Reports

Ephrin-A/EphA specific co-adaptation as a novel mechanism in topographic axon guidance

(2017) Felix Fiederling et al.   eLife

Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2

(2017) Keisuke Onishi et al.   eLife

Slit-Robo signaling

(2016) Heike Blockus et al.   DEVELOPMENT

Calsyntenin 1-mediated trafficking of axon guidance receptors regulates the switch in axonal responsiveness at a choice point

(2016) Tobias A. Alther et al.   DEVELOPMENT

IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories

(2016) Nicolas Preitner et al.   DEVELOPMENT

Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex

(2016) Carlos Oliva et al.   DEVELOPMENTAL CELL

Thalamic neuronal specification and early circuit formation

(2016) Henrik Gezelius et al.   Developmental Neurobiology

Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1

(2016) Hanna Hörnberg et al.   JOURNAL OF NEUROSCIENCE

Commissural axon navigation: Control of midline crossing in the vertebrate spinal cord by the semaphorin 3B signaling

(2016) Aurora Pignata et al.   Cell Adhesion & Migration

ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis

(2016) Filip A. Konopacki et al.   Open Biology

Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons

(2016) Maryam Alavi et al.   PLOS BIOLOGY

Reverse Signaling by Semaphorin-6A Regulates Cellular Aggregation and Neuronal Morphology

(2016) Francesc Perez-Branguli et al.   PLoS One

Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1

(2015) Dan Dascenco et al.   CELL

Phenotypic analysis of mice completely lacking netrin 1

(2015) A. R. Yung et al.   DEVELOPMENT

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases

(2015) Susan van Erp et al.   DEVELOPMENTAL CELL

Netrin-1 induces local translation of down syndrome cell adhesion molecule in axonal growth cones

(2015) Shruti Jain et al.   Developmental Neurobiology

Canonical wnt signaling is required for commissural axon guidance

(2015) Evelyn C. Avilés et al.   Developmental Neurobiology

Secreted Frizzled Related Proteins Modulate Pathfinding and Fasciculation of Mouse Retina Ganglion Cell Axons by Direct and Indirect Mechanisms

(2015) S. Marcos et al.   JOURNAL OF NEUROSCIENCE

Netrin1-DCC-Mediated Attraction Guides Post-Crossing Commissural Axons in the Hindbrain

(2015) Farnaz Shoja-Taheri et al.   JOURNAL OF NEUROSCIENCE

Drosophila melanogaster Hedgehog cooperates with Frazzled to guide axons through a non-canonical signalling pathway

(2015) Delia Ricolo et al.   MECHANISMS OF DEVELOPMENT

Subrepellent doses of Slit1 promote Netrin-1 chemotactic responses in subsets of axons

(2015) Isabelle Dupin et al.   Neural Development

The Intracellular Domain of the Frazzled/DCC Receptor Is a Transcription Factor Required for Commissural Axon Guidance

(2015) Alexandra Neuhaus-Follini et al.   NEURON

Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord

(2015) A. T. Guy et al.   SCIENCE

Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex

(2015) Yohei Shinmyo et al.   Nature Communications

A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist

(2015) Xuefan Gao et al.   Cell Reports

Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death

(2015) Jenea M. Bin et al.   Cell Reports

Integration of Shallow Gradients of Shh and Netrin-1 Guides Commissural Axons

(2015) Tyler F. W. Sloan et al.   PLOS BIOLOGY

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

(2015) Sebastian Poliak et al.   eLife

Neuronal and microglial regulators of cortical wiring: usual and novel guideposts

(2015) Paola Squarzoni   Frontiers in Neuroscience

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

(2014) Dalila Pinto et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Connecting the Retina to the Brain

(2014) Lynda Erskine et al.   ASN Neuro

EphA4 Receptor Shedding Regulates Spinal Motor Axon Guidance

(2014) Graziana Gatto et al.   CURRENT BIOLOGY

FLRT3 Is a Robo1-Interacting Protein that Determines Netrin-1 Attraction in Developing Axons

(2014) Eduardo Leyva-Díaz et al.   CURRENT BIOLOGY

Inputs from the thalamocortical system on axon pathfinding mechanisms

(2014) Sonia Garel et al.   CURRENT OPINION IN NEUROBIOLOGY

The multifaceted roles of Slits and Robos in cortical circuits: from proliferation to axon guidance and neurological diseases

(2014) Heike Blockus et al.   CURRENT OPINION IN NEUROBIOLOGY

Semaphorin signalling during development

(2014) B. C. Jongbloets et al.   DEVELOPMENT

Semaphorin 6B acts as a receptor in post-crossing commissural axon guidance

(2014) I. Andermatt et al.   DEVELOPMENT

Flamingo, a seven-pass transmembrane cadherin, cooperates with Netrin/Frazzled inDrosophilamidline guidance

(2014) Cristina Organisti et al.   GENES TO CELLS

The SynCAM synaptic cell adhesion molecules are involved in sensory axon pathfinding by regulating axon-axon contacts

(2014) J. A. Frei et al.   JOURNAL OF CELL SCIENCE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments

(2014) Céline Delloye-Bourgeois et al.   NATURE NEUROSCIENCE

Signaling Switch of the Axon Guidance Receptor Robo3 during Vertebrate Evolution

(2014) Pavol Zelina et al.   NEURON

Target-Independent EphrinA/EphA-Mediated Axon-Axon Repulsion as a Novel Element in Retinocollicular Mapping

(2014) Philipp Suetterlin et al.   NEURON

ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A

(2014) Erez Romi et al.   Nature Communications

SnapShot: Axon Guidance II

(2013) Alex L. Kolodkin et al.   CELL

Regulation of Axon Guidance by Compartmentalized Nonsense-Mediated mRNA Decay

(2013) Dilek Colak et al.   CELL

SnapShot: Axon Guidance

(2013) R. Jeroen Pasterkamp et al.   CELL

Netrin-DCC Signaling Regulates Corpus Callosum Formation Through Attraction of Pioneering Axons and by Modulating Slit2-Mediated Repulsion

(2013) Thomas Fothergill et al.   CEREBRAL CORTEX

Actin dynamics in growth cone motility and navigation

(2013) Timothy M. Gomez et al.   JOURNAL OF NEUROCHEMISTRY

Switching Responses: Spatial and Temporal Regulators of Axon Guidance

(2013) Andrew Kaplan et al.   MOLECULAR NEUROBIOLOGY

A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease

(2013) Anna Antonell et al.   NEUROBIOLOGY OF AGING

Sonic Hedgehog Regulates Its Own Receptor on Postcrossing Commissural Axons in a Glypican1-Dependent Manner

(2013) Nicole H. Wilson et al.   NEURON

RNA-binding proteins and translational regulation in axons and growth cones

(2013) Hanna Hörnberg et al.   Frontiers in Neuroscience

Multiple Slits regulate the development of midline glial populations and the corpus callosum

(2012) Divya K. Unni et al.   DEVELOPMENTAL BIOLOGY

Genetic Analysis of DSCAM's Role as a Netrin-1 Receptor in Vertebrates

(2012) E. Palmesino et al.   JOURNAL OF NEUROSCIENCE

Diverse types of genetic variation converge on functional gene networks involved in schizophrenia

(2012) Sarah R Gilman et al.   NATURE NEUROSCIENCE

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

(2012) Hosung Jung et al.   NATURE REVIEWS NEUROSCIENCE

Getting neural circuits into shape with semaphorins

(2012) R. Jeroen Pasterkamp   NATURE REVIEWS NEUROSCIENCE

RabGDI controls axonal midline crossing by regulating Robo1 surface expression

(2012) Melanie Philipp et al.   Neural Development

gdnf Activates Midline Repulsion by Semaphorin3B via NCAM during Commissural Axon Guidance

(2012) Camille Charoy et al.   NEURON

14-3-3 Proteins Regulate a Cell-Intrinsic Switch from Sonic Hedgehog-Mediated Commissural Axon Attraction to Repulsion after Midline Crossing

(2012) Patricia T. Yam et al.   NEURON

Optic Chiasm Presentation of Semaphorin6D in the Context of Plexin-A1 and Nr-CAM Promotes Retinal Axon Midline Crossing

(2012) Takaaki Kuwajima et al.   NEURON

Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity

(2011) Christopher J Donnelly et al.   EMBO JOURNAL

Draxin Inhibits Axonal Outgrowth through the Netrin Receptor DCC

(2011) G. Ahmed et al.   JOURNAL OF NEUROSCIENCE

Netrin-1-Induced Local  -Actin Synthesis and Growth Cone Guidance Requires Zipcode Binding Protein 1

(2011) K. Welshhans et al.   JOURNAL OF NEUROSCIENCE

miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones

(2011) Marie-Laure Baudet et al.   NATURE NEUROSCIENCE

Rostral growth of commissural axons requires the cell adhesion molecule MDGA2

(2011) Pascal Joset et al.   Neural Development

VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1

(2011) Carmen Ruiz de Almodovar et al.   NEURON

Slit2 Activity in the Migration of Guidepost Neurons Shapes Thalamic Projections during Development and Evolution

(2011) Franck Bielle et al.   NEURON

VEGF Signaling through Neuropilin 1 Guides Commissural Axon Crossing at the Optic Chiasm

(2011) Lynda Erskine et al.   NEURON

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation

(2010) Joseph Tcherkezian et al.   CELL

Nectin-like molecules/SynCAMs are required for post-crossing commissural axon guidance

(2010) V. Niederkofler et al.   DEVELOPMENT

Wnt/calcium signaling mediates axon growth and guidance in the developing corpus callosum

(2010) B. Ian Hutchins et al.   Developmental Neurobiology

Cis interaction between Semaphorin6A and Plexin-A4 modulates the repulsive response to Sema6A

(2010) Liat Haklai-Topper et al.   EMBO JOURNAL

A midline switch of receptor processing regulates commissural axon guidance in vertebrates

(2010) H. Nawabi et al.   GENES & DEVELOPMENT

The Bone Morphogenetic Protein Roof Plate Chemorepellent Regulates the Rate of Commissural Axonal Growth

(2010) K. D. Phan et al.   JOURNAL OF NEUROSCIENCE

Sonic Hedgehog Guides Post-Crossing Commissural Axons Both Directly and Indirectly by Regulating Wnt Activity

(2010) E. Domanitskaya et al.   JOURNAL OF NEUROSCIENCE

Wnt/Planar Cell Polarity Signaling Controls the Anterior-Posterior Organization of Monoaminergic Axons in the Brainstem

(2010) A. G. Fenstermaker et al.   JOURNAL OF NEUROSCIENCE

Segregation of Ipsilateral Retinal Ganglion Cell Axons at the Optic Chiasm Requires the Shh Receptor Boc

(2010) P. J. Fabre et al.   JOURNAL OF NEUROSCIENCE

Perturbations of MicroRNA Function in Mouse Dicer Mutants Produce Retinal Defects and Lead to Aberrant Axon Pathfinding at the Optic Chiasm

(2010) Rita Pinter et al.   PLoS One

Wiring the Brain: The Biology of Neuronal Guidance

(2010) A. Chedotal et al.   Cold Spring Harbor Perspectives in Biology

Neuropilin 1-Sema Signaling Regulates Crossing of Cingulate Pioneering Axons during Development of the Corpus Callosum

(2009) Michael Piper et al.   CEREBRAL CORTEX

Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing

(2009) Liseth M Parra et al.   NATURE NEUROSCIENCE

Sonic Hedgehog Guides Axons through a Noncanonical, Src-Family-Kinase-Dependent Signaling Pathway

(2009) Patricia T. Yam et al.   NEURON

DSCAM functions as a netrin receptor in commissural axon pathfinding

(2009) Guofa Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Draxin, a Repulsive Guidance Protein for Spinal Cord and Forebrain Commissures

(2009) S. M. Islam et al.   SCIENCE

Analysis of Gene Expression in Parkinson's Disease: Possible Involvement of Neurotrophic Support and Axon Guidance in Dopaminergic Cell Death

(2008) Koen Bossers et al.   BRAIN PATHOLOGY

DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1

(2008) Alice Ly et al.   CELL

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals

(2008) C. O. Law et al.   DEVELOPMENT

Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons

(2008) C. Sanchez-Camacho et al.   DEVELOPMENT

Alternative Splicing of the Robo3 Axon Guidance Receptor Governs the Midline Switch from Attraction to Repulsion

(2008) Zhe Chen et al.   NEURON

The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons

(2007) William Andrews et al.   DEVELOPMENTAL BIOLOGY

Robos are required for the correct targeting of retinal ganglion cell axons in the visual pathway of the brain

(2007) Céline Plachez et al.   MOLECULAR AND CELLULAR NEUROSCIENCE