Diagnostic approach to low-renin hypertension

GENETICS IN ENDOCRINOLOGY: The expanding genetic horizon of primary aldosteronism

(2018) Silvia Monticone et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Liddle Syndrome: Review of the Literature and Description of a New Case

(2018) Martina Tetti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Low-Renin Hypertension Phenotype: Genetics and the Role of the Mineralocorticoid Receptor

(2018) Rene Baudrand et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of the genes involved in Mendelian forms of low-renin hypertension in Chinese early-onset hypertensive patients

(2018) Kai Liu et al.   JOURNAL OF HYPERTENSION

CLCN2 chloride channel mutations in familial hyperaldosteronism type II

(2018) Ute I. Scholl et al.   NATURE GENETICS

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

(2018) Fabio L. Fernandes-Rosa et al.   NATURE GENETICS

Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis

(2018) Silvia Monticone et al.   Lancet Diabetes & Endocrinology

11β-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation

(2017) Rubén Jiménez-Canino et al.   ENDOCRINOLOGY

Confirmatory Tests for the Diagnosis of Primary AldosteronismNovelty and Significance

(2017) Ying Song et al.   HYPERTENSION

Continuum of Renin-Independent Aldosteronism in NormotensionNovelty and Significance

(2017) Rene Baudrand et al.   HYPERTENSION

Familial hyperaldosteronism type III

(2017) S Monticone et al.   JOURNAL OF HUMAN HYPERTENSION

Apparent mineralocorticoid excess

(2017) John W. Funder   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice

(2017) Silvia Monticone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Missense Mutation in the Extracellular Domain ofαENaC Causes Liddle Syndrome

(2017) Mahdi Salih et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Congenital adrenal hyperplasia

(2017) Diala El-Maouche et al.   LANCET

Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11β-hydroxysteroid dehydrogenase type 2 deficiency

(2017) Mabel Yau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

(2017) Tracy A Williams et al.   Lancet Diabetes & Endocrinology

Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

(2016) Israel Hanukoglu et al.   GENE

Suppression of Aldosterone Secretion After Recumbent Saline Infusion Does Not Exclude Lateralized Primary AldosteronismNovelty and Significance

(2016) Erika Cornu et al.   HYPERTENSION

The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline

(2016) John W. Funder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas

(2016) Davide Calebiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Diagnostic accuracy of aldosterone and renin measurement by chemiluminescent immunoassay and radioimmunoassay in primary aldosteronism

(2016) Jacopo Burrello et al.   JOURNAL OF HYPERTENSION

Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation

(2016) Koshiro Nishimoto et al.   International Journal of Endocrinology

Laboratory challenges in primary aldosteronism screening and diagnosis

(2015) Muhammad Rehan et al.   CLINICAL BIOCHEMISTRY

Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype

(2015) Ute I. Scholl et al.   CLINICAL ENDOCRINOLOGY

Pathogenesis of Adrenal Aldosterone-Producing Adenomas Carrying Mutations of the Na+/K+-ATPase

(2015) J. Stindl et al.   ENDOCRINOLOGY

Chrousos syndrome: from molecular pathogenesis to therapeutic management

(2015) Nicolas C. Nicolaides et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Renin and Aldosterone Measurements in the Management of Arterial Hypertension

(2015) A. Viola et al.   HORMONE AND METABOLIC RESEARCH

Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension

(2015) Athina Markou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population

(2015) Lin-Ping Wang et al.   Journal of Clinical Hypertension

Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays

(2015) Jenny Manolopoulou et al.   JOURNAL OF HYPERTENSION

Understanding primary aldosteronism: impact of next generation sequencing and expression profiling

(2015) Silvia Monticone et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

(2015) Koshiro Nishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism

(2015) Ute I Scholl et al.   eLife

Adrenal vein sampling in primary aldosteronism: towards a standardised protocol

(2015) Silvia Monticone et al.   Lancet Diabetes & Endocrinology

Role for Germline Mutations and a Rare Coding Single Nucleotide Polymorphism Within the KCNJ5 Potassium Channel in a Large Cohort of Sporadic Cases of Primary Aldosteronism

(2014) Meena Murthy et al.   HYPERTENSION

Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma

(2014) Fabio Luiz Fernandes-Rosa et al.   HYPERTENSION

Seated Saline Suppression Testing For The Diagnosis Of Primary Aldosteronism: A Preliminary Study

(2014) Ashraf H. Ahmed et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Gordon Syndrome: a continuing story

(2014) Kevin M. O’Shaughnessy   PEDIATRIC NEPHROLOGY

Age-Related Changes in 11 -Hydroxysteroid Dehydrogenase Type 2 Activity in Normotensive Subjects

(2013) C. Campino et al.   AMERICAN JOURNAL OF HYPERTENSION

Evidence of Primary Aldosteronism in a Predominantly Female Cohort of Normotensive Individuals: A Very High Odds Ratio for Progression into Arterial Hypertension

(2013) Athina Markou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Long-Term Cardio- and Cerebrovascular Events in Patients With Primary Aldosteronism

(2013) Paolo Mulatero et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Development of monoclonal antibodies against human CYP11B1 and CYP11B2

(2013) Celso E. Gomez-Sanchez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

(2013) Elena A B Azizan et al.   NATURE GENETICS

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

(2013) Ute I Scholl et al.   NATURE GENETICS

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

(2012) Lynn M. Boyden et al.   NATURE

A liquid chromatography tandem mass spectrometry assay for plasma renin activity using online solid-phase extraction

(2012) S. Carter et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Prevalence and Characteristics of Familial Hyperaldosteronism

(2011) Paolo Mulatero et al.   HYPERTENSION

Mutations of the Potassium Channel KCNJ5 Causing Aldosterone-Producing Adenomas

(2011) Celso E. Gomez-Sanchez et al.   HYPERTENSION

K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

(2011) M. Choi et al.   SCIENCE

Adrenocortical Zonation in Humans under Normal and Pathological Conditions

(2010) Koshiro Nishimoto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A screening procedure for primary aldosteronism based on the Diasorin Liaison(R) automated chemiluminescent immunoassay for direct renin

(2010) C. A. Dorrian et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Age-dependent Decrease in 11 -Hydroxysteroid Dehydrogenase Type 2 (11 -HSD2) Activity in Hypertensive Patients

(2008) J. Henschkowski et al.   AMERICAN JOURNAL OF HYPERTENSION

A Novel Form of Human Mendelian Hypertension Featuring Nonglucocorticoid-Remediable Aldosteronism

(2008) David S. Geller et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline

(2008) John W. Funder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM