Role for Germline Mutations and a Rare Coding Single Nucleotide Polymorphism Within the KCNJ5 Potassium Channel in a Large Cohort of Sporadic Cases of Primary Aldosteronism

Genetic Variations in the KCNJ5 Gene in Primary Aldosteronism Patients from Xinjiang, China

(2013) Nan-Fang Li et al.   PLoS One

Potassium Channel Mutant KCNJ5 T158A Expression in HAC-15 Cells Increases Aldosterone Synthesis

(2012) Kenji Oki et al.   ENDOCRINOLOGY

Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

(2012) Elena A.B. Azizan et al.   HYPERTENSION

A Novel Point Mutation in theKCNJ5Gene Causing Primary Hyperaldosteronism and Early-Onset Autosomal Dominant Hypertension

(2012) Evangelia Charmandari et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

(2012) Meena Murthy et al.   JOURNAL OF HYPERTENSION

Role of KCNJ5 in familial and sporadic primary aldosteronism

(2012) Paolo Mulatero et al.   Nature Reviews Endocrinology

Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter

(2012) Tobias Åkerström et al.   PLoS One

Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5

(2012) U. I. Scholl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural correlates of selectivity and inactivation in potassium channels

(2011) Jason G. McCoy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium

(2011) Matthew R. Whorton et al.   CELL

A comprehensive review of the clinical aspects of primary aldosteronism

(2011) Gian Paolo Rossi   Nature Reviews Endocrinology

K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

(2011) M. Choi et al.   SCIENCE

Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion

(2008) Tanja Brenner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The acidic motif of WNK4 is crucial for its interaction with the K channel ROMK

(2008) Meena Murthy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Development of an Adrenocorticotropin-Responsive Human Adrenocortical Carcinoma Cell Line

(2008) Jeniel Parmar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline

(2008) John W. Funder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM