Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

Primary Aldosteronism andARMC5Variants

(2015) Mihail Zilbermint et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cushing's syndrome

(2015) André Lacroix et al.   LANCET

Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas

(2015) Silvia Monticone et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sodium Deficiency Regulates Rat Adrenal Zona Glomerulosa Gene Expression

(2014) Koshiro Nishimoto et al.   ENDOCRINOLOGY

HRAS mutations are frequent in inverted urothelial neoplasms

(2014) Andrew S. McDaniel et al.   HUMAN PATHOLOGY

Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma

(2014) Fabio Luiz Fernandes-Rosa et al.   HYPERTENSION

Adrenal Nodularity and Somatic Mutations in Primary Aldosteronism: One Node Is the Culprit?

(2014) T. Dekkers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Tumor evolution and progression in multifocal and paired non-invasive/invasive urothelial carcinoma

(2014) Joshua I. Warrick et al.   VIRCHOWS ARCHIV

Diagnosis and management of primary aldosteronism: An updated review

(2013) Chia-Ter Chao et al.   ANNALS OF MEDICINE

Adrenocortical Zonation Results from Lineage Conversion of Differentiated Zona Glomerulosa Cells

(2013) Bethany D. Freedman et al.   DEVELOPMENTAL CELL

Somatic ATP1A1 , ATP2B3 , and KCNJ5 Mutations in Aldosterone-Producing Adenomas

(2013) Tracy Ann Williams et al.   HYPERTENSION

Histopathological Diagnosis of Primary Aldosteronism Using CYP11B2 Immunohistochemistry

(2013) Kazutaka Nanba et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Novel Y152C KCNJ5 Mutation Responsible for Familial Hyperaldosteronism Type III

(2013) Silvia Monticone et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency

(2013) E. S. Husebye et al.   JOURNAL OF INTERNAL MEDICINE

KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling

(2013) Sheerazed Boulkroun et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Development of monoclonal antibodies against human CYP11B1 and CYP11B2

(2013) Celso E. Gomez-Sanchez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

(2013) Elena A B Azizan et al.   NATURE GENETICS

Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism

(2013) Ute I Scholl et al.   NATURE GENETICS

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

(2013) Felix Beuschlein et al.   NATURE GENETICS

ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome

(2013) Guillaume Assié et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours

(2012) Anya Rothenbuhler et al.   CLINICAL ENDOCRINOLOGY

Transcriptome Analysis Reveals Differentially Expressed Transcripts in Rat Adrenal Zona Glomerulosa and Zona Fasciculata

(2012) Koshiro Nishimoto et al.   ENDOCRINOLOGY

Potassium Channel Mutant KCNJ5 T158A Expression in HAC-15 Cells Increases Aldosterone Synthesis

(2012) Kenji Oki et al.   ENDOCRINOLOGY

Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

(2012) Elena A.B. Azizan et al.   HYPERTENSION

Phosphodiesterase 11A (PDE11A) Gene Defects in Patients with ACTH-Independent Macronodular Adrenal Hyperplasia (AIMAH): Functional Variants May Contribute to Genetic Susceptibility of Bilateral Adrenal Tumors

(2012) Delphine Vezzosi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect ofKCNJ5Mutations on Gene Expression in Aldosterone-Producing Adenomas and Adrenocortical Cells

(2012) Silvia Monticone et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors

(2012) Elena A. B. Azizan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

(2012) Meena Murthy et al.   JOURNAL OF HYPERTENSION

wANNOVAR: annotating genetic variants for personal genomes via the web

(2012) Xiao Chang et al.   JOURNAL OF MEDICAL GENETICS

Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter

(2012) Tobias Åkerström et al.   PLoS One

Prevalence of Primary Aldosteronism in Patient's Cohorts and in Population-based Studies - A Review of the Current Literature

(2011) A. Hannemann et al.   HORMONE AND METABOLIC RESEARCH

Acute and chronic regulation of aldosterone production

(2011) Namita G. Hattangady et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

K+ Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

(2011) M. Choi et al.   SCIENCE

Adrenal Cortex Remodeling and Functional Zona Glomerulosa Hyperplasia in Primary Aldosteronism

(2010) Sheerazed Boulkroun et al.   HYPERTENSION

Adrenocortical Zonation in Humans under Normal and Pathological Conditions

(2010) Koshiro Nishimoto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4

(2008) Ginny I. Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY