The Kraken Wakes: induced EMT as a driver of tumour aggression and poor outcome
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Title
The Kraken Wakes: induced EMT as a driver of tumour aggression and poor outcome
Authors
Keywords
Epithelial mesenchymal transition, Resistance, Metastasis, Treatment, Proliferation, Apoptosis
Journal
CLINICAL & EXPERIMENTAL METASTASIS
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-06-08
DOI
10.1007/s10585-018-9906-x
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Note: Only part of the references are listed.- PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation
- (2018) Xin Yao Qiu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- mi R -27b and mi R -34a enhance docetaxel sensitivity of prostate cancer cells through inhibiting epithelial-to-mesenchymal transition by targeting ZEB1
- (2018) Guangwei Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Interleukin-6/signal transducer and activator of transcription 3 promotes prostate cancer resistance to androgen deprivation therapy via regulating pituitary tumor transforming gene 1 expression
- (2018) Shengquan Huang et al. CANCER SCIENCE
- Synergistic and additive effects of ATRA in combination with different anti-tumor compounds
- (2018) Eduarda Schultze et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Chemotherapy induces enrichment of CD47+/CD73+/PDL1+immune evasive triple-negative breast cancer cells
- (2018) Debangshu Samanta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of the tumour transition states occurring during EMT
- (2018) Ievgenia Pastushenko et al. NATURE
- Activity of Eribulin in Patients With Advanced Liposarcoma Demonstrated in a Subgroup Analysis From a Randomized Phase III Study of Eribulin Versus Dacarbazine
- (2017) George D. Demetri et al. JOURNAL OF CLINICAL ONCOLOGY
- Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12
- (2017) Jiangning Tan et al. JOURNAL OF IMMUNOLOGY
- Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study
- (2017) Nico van Zandwijk et al. LANCET ONCOLOGY
- Upholding a role for EMT in breast cancer metastasis
- (2017) Xin Ye et al. NATURE
- The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
- (2017) Angela M. Krebs et al. NATURE CELL BIOLOGY
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- Chemotherapy enhances programmed cell death 1/ligand 1 expression via TGF-β induced epithelial mesenchymal transition in non-small cell lung cancer
- (2017) Soichiro Funaki et al. ONCOLOGY REPORTS
- Cellular and molecular mechanisms underlying alcohol-induced aggressiveness of breast cancer
- (2017) Yongchao Wang et al. PHARMACOLOGICAL RESEARCH
- Optimizing the treatment of bevacizumab as first-line therapy for human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer: an updated meta-analysis of published randomized trials
- (2017) Cunfu Li et al. OncoTargets and Therapy
- Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study
- (2017) Rosina Critelli et al. Cell Death & Disease
- Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma
- (2017) Yan Zhang et al. Oncotarget
- Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen
- (2017) Richard E. Kast et al. Oncotarget
- Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis
- (2017) Jungnam Lee et al. Frontiers in Cellular and Infection Microbiology
- Integrin Activation Contributes to Lower Cisplatin Sensitivity in MV3 Melanoma Cells by Inducing the Wnt Signalling Pathway
- (2017) Maria Piva et al. Cancers
- Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis
- (2016) Katrin Palumbo-Zerr et al. ANNALS OF THE RHEUMATIC DISEASES
- The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling
- (2016) Jin Li et al. BLOOD
- MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome
- (2016) Vaia Stavropoulou et al. CANCER CELL
- Abstract P1-05-03: Predictive value of de novo and induced epithelial-mesenchymal transition in locally advanced breast cancer treated with neoadjuvant chemotherapy
- (2016) AD Redfern et al. CANCER RESEARCH
- Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
- (2016) Y. Lou et al. CLINICAL CANCER RESEARCH
- PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung
- (2016) Sehui Kim et al. HUMAN PATHOLOGY
- Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment
- (2016) Mariko Hirai et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Hypoglycemia Enhances Epithelial-Mesenchymal Transition and Invasiveness, and Restrains the Warburg Phenotype, in Hypoxic HeLa Cell Cultures and Microspheroids
- (2016) Álvaro Marín-Hernández et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Epithelial-mesenchymal plasticity in circulating tumor cells
- (2016) Catherine Alix-Panabières et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial
- (2016) Patrick Schöffski et al. LANCET
- Clinical and pathologic features of lung cancer expressing programmed cell death ligand 1 (PD-L1)
- (2016) Masaki Shimoji et al. LUNG CANCER
- The ERK–ZEB1 pathway mediates epithelial–mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids
- (2016) L-Y Chiu et al. ONCOGENE
- MicroRNA-Mediated Post-Transcriptional Regulation of Epithelial to Mesenchymal Transition in Cancer
- (2016) Golnoush Dehbashi Behbahani et al. PATHOLOGY & ONCOLOGY RESEARCH
- High nuclear expression of Twist1 in the skeletal extramedullary disease of myeloma patients predicts inferior survival
- (2016) Jian-Zhu Yang et al. PATHOLOGY RESEARCH AND PRACTICE
- Slug Is Associated With Tumor Metastasis and Angiogenesis in Ovarian Cancer
- (2016) Anxin Gu et al. Reproductive Sciences
- Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma
- (2016) A. Mishra et al. Cancer Discovery
- Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system
- (2016) Benjamin Garcia-Bloj et al. Oncotarget
- Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity
- (2016) Evelyne Beerling et al. Cell Reports
- Altered Expression and Splicing of ESRP1 in Malignant Melanoma Correlates with Epithelial-Mesenchymal Status and Tumor-Associated Immune Cytolytic Activity
- (2016) J. Yao et al. Cancer Immunology Research
- A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer
- (2016) Takuya Sakamoto et al. PLoS One
- Irrefutable evidence for the use of docetaxel in newly diagnosed metastatic prostate cancer: results from the STAMPEDE and CHAARTED trials
- (2015) Robert J. van Soest et al. BMC Medicine
- Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer
- (2015) S. K. Martin et al. CANCER RESEARCH
- Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines
- (2015) Joseph Cursons et al. Cell Communication and Signaling
- Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion
- (2015) Dominik Nörz et al. CELLULAR SIGNALLING
- All-trans retinoic acid inhibits proliferation, migration, invasion and induces differentiation of hepa1-6 cells through reversing EMT in vitro
- (2015) JIEJIE CUI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- NF-κB signaling plays irreplaceable roles in cisplatin-induced bladder cancer chemoresistance and tumor progression
- (2015) YI SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
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- (2015) Adriana Zanetti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2015) Miguel Martín et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2015) Margaretha A. Skowron et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2015) Jing Li et al. LABORATORY INVESTIGATION
- Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells
- (2015) Panagiotis Bouris et al. MATRIX BIOLOGY
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- HDAC inhibition impedes epithelial–mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer
- (2015) M Ruscetti et al. ONCOGENE
- Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis
- (2015) Shiping Xu et al. PANCREAS
- The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma
- (2015) Rachel Ramsdale et al. Science Signaling
- Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail
- (2015) Jutao Feng et al. Cell Adhesion & Migration
- MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1
- (2015) Shichang Deng et al. Oncotarget
- Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop
- (2015) Zhengyan Yang et al. Oncotarget
- Inhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro
- (2015) Elad Sintov et al. Scientific Reports
- The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma
- (2015) Rachel Ramsdale et al. Science Signaling
- Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
- (2015) Mohit Kumar Jolly Frontiers in Oncology
- Clinical Implications of Circulating Tumor Cells of Breast Cancer Patients: Role of Epithelial–Mesenchymal Plasticity
- (2015) Linda M. McInnes et al. Frontiers in Oncology
- Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma
- (2015) Aparna Jayachandran et al. Oncotarget
- Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2†
- (2014) M. Piccart et al. ANNALS OF ONCOLOGY
- Breast cancer stem cells, EMT and therapeutic targets
- (2014) Srishti Kotiyal et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cigarette smoke-induced alveolar epithelial–mesenchymal transition is mediated by Rac1 activation
- (2014) Hui-juan Shen et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies
- (2014) Chris Twelves et al. BREAST CANCER RESEARCH AND TREATMENT
- Suppression of triple-negative breast cancer metastasis by pan-DAC inhibitor panobinostat via inhibition of ZEB family of EMT master regulators
- (2014) Lyndsay V. Rhodes et al. BREAST CANCER RESEARCH AND TREATMENT
- Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states
- (2014) T Yoshida et al. BRITISH JOURNAL OF CANCER
- Acidic extracellular pH promotes epithelial mesenchymal transition in Lewis lung carcinoma model
- (2014) Atsuko Suzuki et al. Cancer Cell International
- Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
- (2014) G Denecker et al. CELL DEATH AND DIFFERENTIATION
- Contribution of acidic melanoma cells undergoing epithelial-to-mesenchymal transition to aggressiveness of non-acidic melanoma cells
- (2014) Silvia Peppicelli et al. CLINICAL & EXPERIMENTAL METASTASIS
- Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients
- (2014) T. Z. Tan et al. EMBO Molecular Medicine
- Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas
- (2014) Shuji Mikami et al. INTERNATIONAL JOURNAL OF CANCER
- Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study
- (2014) Grant A McArthur et al. LANCET ONCOLOGY
- Epithelial-to-Mesenchymal Transition Mediates Docetaxel Resistance and High Risk of Relapse in Prostate Cancer
- (2014) M. Marin-Aguilera et al. MOLECULAR CANCER THERAPEUTICS
- Oncogenic roles of EMT-inducing transcription factors
- (2014) Alain Puisieux et al. NATURE CELL BIOLOGY
- Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia
- (2014) X Zhang et al. ONCOGENE
- Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes
- (2014) Alexander Krohn et al. PLoS One
- IL-17/miR-192/IL-17Rs Regulatory Feedback Loop Facilitates Multiple Myeloma Progression
- (2014) Yuanyuan Sun et al. PLoS One
- Twist-1, A Novel Regulator of Hematopoietic Stem Cell Self-Renewal and Myeloid Lineage Development
- (2014) Cheng-Ya Dong et al. STEM CELLS
- Prognostic significance of the epithelial-to-mesenchymal transition markers e-cadherin, vimentin and twist in bladder cancer
- (2014) Jun Zhao et al. International Braz J Urol
- Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
- (2014) Limo Chen et al. Nature Communications
- Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
- (2014) Suling Liu et al. Stem Cell Reports
- Synergistic antitumor effects of S-1 with eribulin in vitro and in vivo for triple-negative breast cancer cell lines
- (2014) Masato Terashima et al. SpringerPlus
- Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis
- (2013) Denise A. Yardley et al. ADVANCES IN THERAPY
- Inducible Knockout of Twist1 in Young and Adult Mice Prolongs Hair Growth Cycle and Has Mild Effects on General Health, Supporting Twist1 as a Preferential Cancer Target
- (2013) Yan Xu et al. AMERICAN JOURNAL OF PATHOLOGY
- Epithelial-mesenchymal Transition and Its Role in the Pathogenesis of Colorectal Cancer
- (2013) Qing-Chao Zhu et al. Asian Pacific Journal of Cancer Prevention
- The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer
- (2013) Yan Ni Loh et al. BMC CANCER
- E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors
- (2013) Gwen Jordaan et al. BMC CANCER
- Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin
- (2013) Preeti Shah et al. BREAST CANCER RESEARCH AND TREATMENT
- Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models
- (2013) Maria Jure-Kunkel et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Technical considerations for analyzing EMT–MET data from surgical samples
- (2013) Kazuhiko Aoyagi et al. CANCER LETTERS
- ERK1/2 Blockade Prevents Epithelial-Mesenchymal Transition in Lung Cancer Cells and Promotes Their Sensitivity to EGFR Inhibition
- (2013) J. M. Buonato et al. CANCER RESEARCH
- Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis
- (2013) J. M. Low-Marchelli et al. CANCER RESEARCH
- Twist2 functions as a tumor suppressor in murine osteosarcoma cells
- (2013) Tomoki Ishikawa et al. CANCER SCIENCE
- The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma
- (2013) E Sánchez-Tilló et al. CELL DEATH AND DIFFERENTIATION
- Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts
- (2013) Shinichiro Miyazaki et al. INTERNATIONAL JOURNAL OF CANCER
- Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor
- (2013) Denise A. Yardley et al. JOURNAL OF CLINICAL ONCOLOGY
- Multi-Drug–Resistant Cells Enriched From Chronic Myeloid Leukemia Cells by Doxorubicin Possess Tumor-Initiating–Cell Properties
- (2013) Hong Xin et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells
- (2013) Chen Qu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- ZEB1 Imposes a Temporary Stage-Dependent Inhibition of Muscle Gene Expression and Differentiation via CtBP-Mediated Transcriptional Repression
- (2013) L. Siles et al. MOLECULAR AND CELLULAR BIOLOGY
- Epithelial-mesenchymal transition leads to crizotinib resistance in H2228 lung cancer cells with EML4-ALK translocation
- (2013) Hyeong Ryul Kim et al. Molecular Oncology
- Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells
- (2013) Yong-Rong Yan et al. NEUROPATHOLOGY
- Mesenchymal phenotype after chemotherapy is associated with chemoresistance and poor clinical outcome in esophageal cancer
- (2013) JOHJI HARA et al. ONCOLOGY REPORTS
- Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer
- (2013) Fernanda S. Giudice et al. PLoS One
- Twist1 Controls Lung Vascular Permeability and Endotoxin-Induced Pulmonary Edema by Altering Tie2 Expression
- (2013) Tadanori Mammoto et al. PLoS One
- Spontaneous Epithelial-Mesenchymal Transition and Resistance to HER-2-Targeted Therapies in HER-2-Positive Luminal Breast Cancer
- (2013) David Lesniak et al. PLoS One
- Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
- (2013) M. Yu et al. SCIENCE
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- (2013) Marko Stankic et al. Cell Reports
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- (2012) Martin Puhr et al. AMERICAN JOURNAL OF PATHOLOGY
- EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
- (2012) Alexandria M Haslehurst et al. BMC CANCER
- Pooled analysis of individual patient data from capecitabine monotherapy clinical trials in locally advanced or metastatic breast cancer
- (2012) Joanne L. Blum et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2012) N. P. A. Devika Gunasinghe et al. CANCER AND METASTASIS REVIEWS
- Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway
- (2012) Vesselina G. Cooke et al. CANCER CELL
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- (2012) Oscar H. Ocaña et al. CANCER CELL
- Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis
- (2012) Jeff H. Tsai et al. CANCER CELL
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- (2012) Siria Lemma et al. HISTOPATHOLOGY
- Onset Time of Tumor Repopulation for Cervical Cancer: First Evidence From Clinical Data
- (2012) Zhibin Huang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma
- (2012) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The relationships between snail1 and estrogen receptor signaling in breast cancer cells
- (2012) Alexander M. Scherbakov et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Inhibition of ZEB1 reverses EMT and chemoresistance in docetaxel-resistant human lung adenocarcinoma cell line
- (2012) Jin Ren et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
- (2012) Toni Celià-Terrassa et al. JOURNAL OF CLINICAL INVESTIGATION
- Smoking Induces Epithelial-to-Mesenchymal Transition in Non-Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
- (2012) N. S. Nagathihalli et al. MOLECULAR CANCER THERAPEUTICS
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- (2012) Wen-Hao Yang et al. NATURE CELL BIOLOGY
- Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System
- (2012) Qinjie Weng et al. NEURON
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- (2011) Aaron P. Putzke et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2011) Yasushi Shintani et al. ANNALS OF THORACIC SURGERY
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- (2011) Cristina Raimondi et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2011) M. K. Asiedu et al. CANCER RESEARCH
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- (2011) L. Rosano et al. CLINICAL CANCER RESEARCH
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- (2011) Fen Yang et al. EMBO JOURNAL
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- (2011) Huiguang Yang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2011) Ali Aghdassi et al. GUT
- Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity
- (2011) S. H. Thathia et al. HAEMATOLOGICA
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- (2011) Hua Xiong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Aidong Shen et al. JOURNAL OF SURGICAL ONCOLOGY
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- (2011) E W Thompson et al. NATURE MEDICINE
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- (2011) Manav Korpal et al. NATURE MEDICINE
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- (2011) Amir-Shaya Sharili et al. TUMOR BIOLOGY
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- (2011) M Saxena et al. Cell Death & Disease
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- (2010) Turgut Tukel et al. AMERICAN JOURNAL OF HUMAN GENETICS
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- (2010) E. Cosset et al. BLOOD
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- (2010) Manuela Mancini et al. CELLULAR SIGNALLING
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- (2010) Núria Montserrat et al. HUMAN PATHOLOGY
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- Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
- (2010) Johann Sebastian de Bono et al. LANCET
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- (2010) Yvonne L Chao et al. Molecular Cancer
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- (2010) Stephanie H. Shirley et al. MOLECULAR CARCINOGENESIS
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma
- (2010) S Nakahata et al. ONCOGENE
- ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
- (2010) E Sánchez-Tilló et al. ONCOGENE
- Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition
- (2010) T Lin et al. ONCOGENE
- Quiescent, Slow-Cycling Stem Cell Populations in Cancer: A Review of the Evidence and Discussion of Significance
- (2010) Nathan Moore et al. Journal of Oncology
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- (2009) Shi Zhong Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2009) S. Sharma et al. BLOOD
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- (2009) Chie Kudo-Saito et al. CANCER CELL
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
- (2009) Y. Li et al. CANCER RESEARCH
- Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth
- (2009) M. Shiota et al. CANCER RESEARCH
- A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer
- (2009) Theresa A. DiMeo et al. CANCER RESEARCH
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
- (2009) Piyush B. Gupta et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Preclinical Drug Development Must Consider the Impact on Metastasis
- (2009) P. S. Steeg et al. CLINICAL CANCER RESEARCH
- miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy
- (2009) L. Adam et al. CLINICAL CANCER RESEARCH
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2)
- (2009) Laurie G. Hudson et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas
- (2008) Helena Wensman et al. BREAST CANCER RESEARCH AND TREATMENT
- Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype
- (2008) D. Sarrio et al. CANCER RESEARCH
- Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
- (2008) T. Tsuji et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
- Twist-2 Controls Myeloid Lineage Development and Function
- (2008) Andrew B Sharabi et al. PLOS BIOLOGY
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