Interleukin-6/signal transducer and activator of transcription 3 promotes prostate cancer resistance to androgen deprivation therapy via regulating pituitary tumor transforming gene 1 expression

PTTG1, A novel androgen responsive gene is required for androgen-induced prostate cancer cell growth and invasion

(2017) Zheng Zhang et al.   EXPERIMENTAL CELL RESEARCH

TRIM-ing Ligand Dependence in Castration-Resistant Prostate Cancer

(2016) Lalit R. Patel et al.   CANCER CELL

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

(2016) Domenico Albino et al.   Oncotarget

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

(2015) Hong Liu et al.   CARCINOGENESIS

Targeting Cancer Stem Cells in Castration-Resistant Prostate Cancer

(2015) E.-J. Yun et al.   CLINICAL CANCER RESEARCH

Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals

(2015) Xianfan Ding et al.   Molecular Cancer

Metformin Sensitizes EGFR-TKI-Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal

(2014) L. Li et al.   CLINICAL CANCER RESEARCH

Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancer

(2014) Ping Li et al.   Molecular Cancer

PTTG1 inhibits SMAD3 in prostate cancer cells to promote their proliferation

(2014) Shengquan Huang et al.   TUMOR BIOLOGY

Prostate cancer research in China

(2013) Shan-Cheng Ren et al.   ASIAN JOURNAL OF ANDROLOGY

Expression of Pituitary Tumor Transforming Gene 1 is an Independent Factor of Poor Prognosis in Localized or Locally Advanced Prostate Cancer Cases Receiving Hormone Therapy

(2013) Xi-Liang Cao et al.   Asian Pacific Journal of Cancer Prevention

Inflammation and prostate cancer: the role of interleukin 6 (IL-6)

(2013) Daniel P. Nguyen et al.   BJU INTERNATIONAL

GEMMs Shine a Light on Resistance to Androgen Deprivation Therapy for Prostate Cancer

(2013) Theodoros Karantanos et al.   CANCER CELL

Generation of Prostate Tumor-Initiating Cells Is Associated with Elevation of Reactive Oxygen Species and IL-6/STAT3 Signaling

(2013) Y. Qu et al.   CANCER RESEARCH

New insights into prostate cancer stem cells

(2013) Xin Chen et al.   CELL CYCLE

Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells

(2013) Seog-Young Kim et al.   CELLULAR SIGNALLING

World Medical Association Declaration of Helsinki

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility

(2013) C Zhou et al.   ONCOGENE

Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells

(2013) Chengfei Liu et al.   PROSTATE

Expression of the PTTG1 Oncogene Is Associated with Aggressive Clear Cell Renal Cell Carcinoma

(2012) B. Wondergem et al.   CANCER RESEARCH

PTTG1Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell Population

(2012) Chang-Hwan Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin

(2011) Parag P. Shah et al.   CANCER LETTERS

Metastatic Cells Can Escape the Proapoptotic Effects of TNF-  through Increased Autocrine IL-6/STAT3 Signaling

(2011) S. Li et al.   CANCER RESEARCH

Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy

(2011) Y. Sun et al.   CANCER RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2

(2009) S. Feng et al.   MOLECULAR CANCER THERAPEUTICS

CD44+CD24− prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

(2008) E M Hurt et al.   BRITISH JOURNAL OF CANCER

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer

(2008) Sandra E Ghayad et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY