Discovery of Benzimidazole-Quinolone Hybrids as New Cleaving Agents toward Drug-Resistant Pseudomonas aeruginosa DNA

Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation

(2018) Han-Bo Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

(2018) Wei-Wei Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

(2017) N.S. El-Gohary et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and antimicrobial evaluation of novel benzimidazole-incorporated sulfonamide analogues

(2017) Hui-Zhen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs

(2017) N.S. El-Gohary et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial 2-aminothiazolyl quinolones: what is their potential in the clinic?

(2017) Wei-Wei Gao et al.   Future Medicinal Chemistry

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis

(2017) W. David Hong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Supramolecular Conjugated Polymer Systems with Controlled Antibacterial Activity

(2017) Haotian Bai et al.   LANGMUIR

Synthesis, X-ray Single Crystal Structure, Molecular Docking and DFT Computations on N-[(1E)-1-(2H-1,3-Benzodioxol-5-yl)-3-(1H-imidazol-1-yl)propylidene]-hydroxylamine: A New Potential Antifungal Agent Precursor

(2017) Reem Al-Wabli et al.   MOLECULES

Next-generation approaches to understand and combat the antibiotic resistome

(2017) Terence S. Crofts et al.   NATURE REVIEWS MICROBIOLOGY

Cobalt(III)- and Rhodium(III)-Catalyzed C–H Amidation and Synthesis of 4-Quinolones: C–H Activation Assisted by Weakly Coordinating and Functionalizable Enaminone

(2017) Fen Wang et al.   ORGANIC LETTERS

Design, synthesis and biological evaluation of amino organophosphorus imidazoles as a new type of potential antimicrobial agents

(2017) Wei-Wei Gao et al.   Science China-Chemistry

Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration

(2017) Yuan Zhang et al.   MedChemComm

Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents

(2016) Xue-Jie Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Halogen Bond

(2016) Gabriella Cavallo et al.   CHEMICAL REVIEWS

Recent Development of Benzimidazole-Containing Antibacterial Agents

(2016) Di Song et al.   ChemMedChem

Heterocyclic Naphthalimides as New Skeleton Structure of Compounds with Increasingly Expanding Relational Medicinal Applications

(2016) Huo-Hui Gong et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Benzimidazole-thiazole based NLOphoric styryl dyes with solid state emission – Synthesis, photophysical, hyperpolarizability and TD-DFT studies

(2016) Rajratna P. Tayade et al.   DYES AND PIGMENTS

Design, synthesis and biological evaluation of novel benzimidazole-2-substituted phenyl or pyridine propyl ketene derivatives as antitumour agents

(2016) Lin-tao Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents

(2016) Ponmani Jeyakkumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents

(2016) Ling Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells

(2016) Yu Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinazolinone azolyl ethanols: potential lead antimicrobial agents with dual action modes targeting methicillin-resistantStaphylococcus aureusDNA

(2016) Xin-Mei Peng et al.   Future Medicinal Chemistry

Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

(2016) Sheng-Feng Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms of the Antimicrobial Activities of Graphene Materials

(2016) Xuefeng Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and biological evaluation of Schiff base-linked imidazolyl naphthalimides as novel potential anti-MRSA agents

(2016) Huo-Hui Gong et al.   MedChemComm

Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu2+ mediated DNA-targeting antibacterial agents

(2015) Ling Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Antimicrobial Evaluation of Novel Quinolone Imidazoles and Interactions with MRSA DNA

(2015) Ling Zhang et al.   Chemical Biology & Drug Design

Synthesis and evaluation of antimycobacterial activity of new benzimidazole aminoesters

(2015) Yeong Keng Yoon et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Origins of the Quinolone Class of Antibacterials: An Expanded “Discovery Story”

(2015) Gregory S. Bisacchi   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel sulfonamide azoles via C–N cleavage of sulfonamides by azole ring and relational antimicrobial study

(2015) Hui-Zhen Zhang et al.   NEW JOURNAL OF CHEMISTRY

Novel benzimidazole derived naphthalimide triazoles: synthesis, antimicrobial activity and interactions with calf thymus DNA

(2015) Yun-Lei Luo et al.   Science China-Chemistry

Design, synthesis, and antibacterial evaluation of novel azolylthioether quinolones as MRSA DNA intercalators

(2015) Ling Zhang et al.   MedChemComm

Synthesis and biological evaluation of a new class of quinazolinoneazoles as potential antimicrobial agents and their interactions with calf thymus DNA and human serum albumin

(2015) Li-Ping Peng et al.   MedChemComm

Orthogonal Control of Antibacterial Activity with Light

(2014) Willem A. Velema et al.   ACS Chemical Biology

Novel hybrids of metronidazole and quinolones: Synthesis, bioactive evaluation, cytotoxicity, preliminary antimicrobial mechanism and effect of metal ions on their transportation by human serum albumin

(2014) Sheng-Feng Cui et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Benzimidazoles as new scaffold of sirtuin inhibitors: Green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties

(2014) Yeong Keng Yoon et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Metal-Free TEMPO-Promoted C(sp3)–H Amination To Afford Multisubstituted Benzimidazoles

(2014) Ding Xue et al.   JOURNAL OF ORGANIC CHEMISTRY

A unique one-pot reaction via CC cleavage from aminomethylene benzimidazoles to access benzimidazolones with wide potentiality

(2014) Hui-Zhen Zhang et al.   TETRAHEDRON LETTERS

Synthesis and biological evaluation of a class of quinolone triazoles as potential antimicrobial agents and their interactions with calf thymus DNA

(2013) Sheng-Feng Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Current Developments in the Syntheses of 1,2,4-Triazole Compounds

(2013) Hui-Zhen Zhang et al.   CURRENT ORGANIC CHEMISTRY

Current Developments of Coumarin Compounds in Medicinal Chemistry

(2013) Xin-Mei Peng et al.   CURRENT PHARMACEUTICAL DESIGN

Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents

(2013) Xin-Mei Peng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin

(2013) Ben-Tao Yin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Optical control of antibacterial activity

(2013) Willem A. Velema et al.   Nature Chemistry

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Study on the interaction of the antiviral drug, zidovudine with DNA using neutral red (NR) and methylene blue (MB) dyes

(2012) Nahid Shahabadi et al.   JOURNAL OF LUMINESCENCE

Molecular Spectroscopic Studies of Farrerol Interaction with Calf Thymus DNA

(2011) Guowen Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Halogen Atoms in the Modern Medicinal Chemistry: Hints for the Drug Design

(2010) Marcelo Hernandes et al.   CURRENT DRUG TARGETS

A Small-Molecule Inhibitor of Nipah Virus Envelope Protein-Mediated Membrane Fusion

(2009) Sabine Niedermeier et al.   JOURNAL OF MEDICINAL CHEMISTRY