Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells

Antitumorigenic effect of plumbagin by induction of SH2-containing protein tyrosine phosphatase 1 in human gastric cancer cells

(2015) MOON KYUNG JOO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Downregulation of P-gp, Ras and p-ERK1/2 contributes to the arsenic trioxide-induced reduction in drug resistance towards doxorubicin in gastric cancer cell lines

(2015) YUAN-YUAN ZHAO et al.   Molecular Medicine Reports

SHP-1 is a negative regulator of epithelial–mesenchymal transition in hepatocellular carcinoma

(2015) L-C Fan et al.   ONCOGENE

Targeting JAK kinase in solid tumors: emerging opportunities and challenges

(2015) M Buchert et al.   ONCOGENE

Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells

(2015) Moon Kyung Joo et al.   TUMOR BIOLOGY

Phase I Study of OPB-31121, an Oral STAT3 Inhibitor, in Patients with Advanced Solid Tumors

(2015) Do-Youn Oh et al.   Cancer Research and Treatment

STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma

(2014) W.-T. Tai et al.   CLINICAL CANCER RESEARCH

TMEFF2 Deregulation Contributes to Gastric Carcinogenesis and Indicates Poor Survival Outcome

(2014) T. Sun et al.   CLINICAL CANCER RESEARCH

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention

(2014) Samantha Kaufhold et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Therapeutic Inhibition of Jak Activity Inhibits Progression of Gastrointestinal Tumors in Mice

(2014) E. Stuart et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inactivation of Akt by arsenic trioxide induces cell death via mitochondrial-mediated apoptotic signaling in SGC-7901 human gastric cancer cells

(2014) YAN-HUI GAO et al.   ONCOLOGY REPORTS

Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases

(2013) Jong Hyun Lee et al.   CANCER LETTERS

Discovery of novel src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma

(2013) Wei-Tien Tai et al.   HEPATOLOGY

Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway

(2013) Shuling Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters

(2013) Vincent Petit et al.   LABORATORY INVESTIGATION

SHP-1 in Cell-Cycle Regulation

(2012) Pilar Lopez-Ruiz et al.   Anti-Cancer Agents in Medicinal Chemistry

Targeting STAT3 in gastric cancer

(2012) Andrew S Giraud et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

HOXB7 as a Prognostic Factor and Mediator of Colorectal Cancer Progression

(2011) W.-T. Liao et al.   CLINICAL CANCER RESEARCH

Dovitinib Induces Apoptosis and Overcomes Sorafenib Resistance in Hepatocellular Carcinoma through SHP-1-Mediated Inhibition of STAT3

(2011) W.-T. Tai et al.   MOLECULAR CANCER THERAPEUTICS

Responsive nematic gels from the self-assembly of aqueous nanofibres

(2011) Zhegang Huang et al.   Nature Communications

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

(2010) K.-F. Chen et al.   CLINICAL CANCER RESEARCH

Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation

(2009) Yingchun Li et al.   CANCER LETTERS

STAT3 as a prognostic marker in human gastric cancer

(2009) Cameron B Jackson et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS